Name

Temsirolimus

Alternate Names

AP23573
CCI 779
CCI-779
CCI779
Torisel
rapamycin analog
rapamycin ester

Abbreviations

None

Category

Chemotherapy

Subcategory

Cytostatic agent--antiangiogenic agent
mTOR inhibitor

NSC Number

683864

Primary Site

Kidney
Mantle cell lymphoma
breast
colorectal
lung
ovarian
pancreatic
prostate cancer
sarcoma

Histology

None

Remarks

FDA approved for renal cell carcinoma of the kidney 2007; in trials for breast, colorectal, lung, pancreatic, prostate, sarcoma. Second generation mTOR inhibitor.

NOTE: this drug is a type of rapamycin analog/rapamycin ester and should not be confused with the drug "Rapamycin, NOS" which is used to treat GVHD (graft versus host disease) for transplant patients. Careful review of the medical record should be done to dtermine which drug was given and for what reason.

Coding

This drug should be coded
Glossary