The table below provides the definition for this International Classification of Childhood Cancer, Third edition (ICCC-3) variable. To see other variable definitions, see the ICCC home page.

Caution: The ICCC recode in the SEER databases through the November 2011 submission incorrectly classifies some benign and borderline tumors into specific groups. Benign and borderline tumors should only be in III (all sub categories) and X(a). Please group all other benign and borderline tumors with non-classifiable. This problem was fixed starting with the November 2012 submission.

Site Group ICD-O-3 Histology (Type) ICD-O-2/3 Site Recode for Extended Classification
I. Leukemias, myeloproliferative diseases, and myelodysplastic diseases
(a) Lymphoid leukemias
(a.1) Precursor cell leukemias 9835, 9836, 9837 C000-C809 001
(a.2) Mature B-cell leukemias 9823, 9826, 9832, 9833, 9940 C000-C809 002
(a.3) Mature T-cell and NK cell leukemias 9827, 9831, 9834, 9948 C000-C809 003
(a.4) Lymphoid leukemia, NOS 9820 C000-C809 004
(b) Acute myeloid leukemias 9840, 9861, 9866, 9867, 9870-9874, 9891, 9895-9897, 9910, 9920, 9931 C000-C809 005
(c) Chronic myeloproliferative diseases 9863, 9875, 9876, 9950, 9960-9964 C000-C809 006
(d) Myelodysplastic syndrome and other myeloproliferative diseases 9945, 9946, 9975, 9980, 9982-9987, 9989 C000-C809 007
(e) Unspecified and other specified leukemias 9800, 9801, 9805, 9860, 9930 C000-C809 008
II. Lymphomas and reticuloendothelial neoplasms
(a) Hodgkin lymphomas 9650-9655, 9659, 9661-9665, 9667 C000-C809 009
(b) Non-Hodgkin lymphomas (except Burkitt lymphoma)
(b.1) Precursor cell lymphomas 9727-9729 C000-C809 010
(b.2) Mature B-cell lymphomas (except Burkitt lymphoma) 9670, 9671, 9673, 9675, 9678-9680, 9684, 9689-9691, 9695, 9698, 9699, 9731-9734, 9761, 9762, 9764-9766, 9769, 9970 C000-C809 011
(b.3) Mature T-cell and NK-cell lymphomas 9700-9702, 9705, 9708, 9709, 9714, 9716-9719, 9767, 9768 C000-C809 012
(b.4) Non-Hodgkin lymphomas, NOS 9591, 9760 C000-C809 013
(c) Burkitt lymphoma 9687 C000-C809 014
(d) Miscellaneous lymphoreticular neoplasms 9740-9742, 9750, 9754-9758 C000-C809 015
(e) Unspecified lymphomas 9590, 9596 C000-C809 016
III. CNS and miscellaneous intracranial and intraspinal neoplasms
(a) Ependymomas and choroid plexus tumor
(a.1) Ependymomas 9383, 9391-9394 C000-C809 017
(a.2) Choroid plexus tumor 9390 C000-C809 018
(b) Astrocytomas 9380 C723 019
9384, 9400-9411, 9420, 9421-9424, 9440-9442 C000-C809 019
(c) Intracranial and intraspinal embryonal tumors
(c.1) Medulloblastomas 9470-9472, 9474, 9480 C000-C809 020
(c.2) PNET 9473 C000-C809 021
(c.3) Medulloepithelioma 9501-9504 C700-C729 022
(c.4) Atypical teratoid/rhabdoid tumor 9508 C000-C809 023
(d) Other gliomas
(d.1) Oligodendrogliomas 9450, 9451, 9460 C000-C809 024
(d.2) Mixed and unspecified gliomas 9380 C700-C722, C724-C729, C751, C753 025
9382 C000-C809 025
(d.3) Neuroepithelial glial tumors of uncertain origin 9381, 9430, 9444 C000-C809 026
(e) Other specified intracranial and intraspinal neoplasms
(e.1) Pituitary adenomas and carcinomas 8270-8281, 8300 C000-C809 027
(e.2) Tumors of the sellar region (craniopharyngiomas) 9350-9352, 9582 C000-C809 028
(e.3) Pineal parenchymal tumors 9360-9362 C000-C809 029
(e.4) Neuronal and mixed neuronal-glial tumors 9412, 9413, 9492, 9493, 9505-9507 C000-C809 030
(e.5) Meningiomas 9530-9539 C000-C809 031
(f) Unspecified intracranial and intraspinal neoplasms 8000-8005 C700-C729, C751-C753 032
IV. Neuroblastoma and other peripheral nervous cell tumors
(a) Neuroblastoma and ganglioneuroblastoma 9490, 9500 C000-C809 033
(b) Other peripheral nervous cell tumors 8680-8683, 8690-8693, 8700, 9520-9523 C000-C809 034
9501-9504 C000-C699, C739-C768, C809 034
V. Retinoblastoma 9510-9514 C000-C809 035
VI. Renal tumors
(a) Nephroblastoma and other nonepithelial renal tumors
(a.1) Nephroblastoma 8959, 8960 C000-C809 036
(a.2) Rhabdoid renal tumor 8963 C649 037
(a.3) Kidney sarcomas 8964-8967 C000-C809 038
(a.4) pPNET of kidney 9364 C649 039
(b) Renal carcinomas 8010-8041, 8050-8075, 8082, 8120-8122, 8130-8141, 8143, 8155, 8190-8201, 8210, 8211, 8221-8231, 8240, 8241, 8244-8246, 8260-8263, 8290, 8310, 8320, 8323, 8401, 8430, 8440, 8480-8490, 8504, 8510, 8550, 8560-8576 C649 040
8311, 8312, 8316-8319, 8361 C000-C809 040
(c) Unspecified malignant renal tumors 8000-8005 C649 041
VII. Hepatic tumors
(a) Hepatoblastoma 8970 C000-C809 042
(b) Hepatic carcinomas 8010-8041, 8050-8075, 8082, 8120-8122, 8140, 8141, 8143, 8155, 8190-8201, 8210, 8211, 8230, 8231, 8240, 8241, 8244-8246, 8260-8264, 8310, 8320, 8323, 8401, 8430, 8440, 8480-8490, 8504, 8510, 8550, 8560-8576 C220, C221 043
8160-8180 C000-C809 043
(c) Unspecified malignant hepatic tumors 8000-8005 C220-C221 044
VIII. Malignant bone tumors
(a) Osteosarcomas 9180-9187, 9191-9195, 9200 C400-C419, C760-C768, C809 045
(b) Chondrosarcomas 9210, 9220, 9240 C400-C419, C760-C768, C809 046
9221, 9230, 9241-9243 C000-C809 046
(c) Ewing tumor and related sarcomas of bone
(c.1) Ewing tumor and Askin tumor of bone 9260 C400-C419, C760-C768, C809 047
9365 C400-C419 047
(c.2) pPNET of bone 9363, 9364 C400-C419 048
(d) Other specified malignant bone tumors
(d.1) Malignant fibrous neoplasms of bone 8810, 8811, 8823, 8830 C400-C419 049
8812, 9262 C000-C809 049
(d.2) Malignant chordomas 9370-9372 C000-C809 050
(d.3) Odontogenic malignant tumors 9270-9275, 9280-9282, 9290, 9300-9302, 9310-9312, 9320-9322, 9330, 9340-9342 C000-C809 051
(d.4) Miscellaneous malignant bone tumors 9250, 9261 C000-C809 052
(e) Unspecified malignant bone tumors 8000-8005, 8800, 8801, 8803-8805 C400-C419 053
IX. Soft tissue and other extraosseous sarcomas
(a) Rhabdomyosarcomas 8900-8905, 8910, 8912, 8920, 8991 C000-C809 054
(b) Fibrosarcomas, peripheral nerve sheath tumors, and other fibrous neoplasms
(b.1) Fibroblastic and myofibroblastic tumors 8810, 8811, 8813-8815, 8821, 8823, 8834-8835 C000-C399, C440-C768, C809 055
8820, 8822, 8824-8827, 9150, 9160 C000-C809 055
(b.2) Nerve sheath tumors 9540-9571 C000-C809 056
(b.3) Other fibromatous neoplasms 9491, 9580 C000-C809 057
(c) Kaposi sarcoma 9140 C000-C809 058
(d) Other specified soft tissue sarcomas
(d.1) Ewing tumor and Askin tumor of soft tissue 9260 C000-C399, C470-C759 059
9365 C000-C399, C470-C639, C659-C768, C809 059
(d.2) pPNET of soft tissue 9364 C000-C399, C470-C639, C659-C699, C739-C768, C809 060
(d.3) Extrarenal rhabdoid tumor 8963 C000-C639, C659-C699, C739-C768, C809 061
(d.4) Liposarcomas 8850-8858, 8860-8862, 8870, 8880, 8881 C000-C809 062
(d.5) Fibrohistiocytic tumors 8830 C000-C399, C440-C768, C809 063
8831-8833, 8836, 9251, 9252 C000-C809 063
(d.6) Leiomyosarcomas 8890-8898 C000-C809 064
(d.7) Synovial sarcomas 9040-9044 C000-C809 065
(d.8) Blood vessel tumors 9120-9125, 9130-9133, 9135, 9136, 9141, 9142, 9161, 9170-9175 C000-C809 066
(d.9) Osseous and chondromatous neoplasms of soft tissue 9180, 9210, 9220, 9240 C490-C499 067
9231 C000-C809 067
(d.10) Alveolar soft parts sarcoma 9581 C000-C809 068
(d.11) Miscellaneous soft tissue sarcomas 8587, 8710-8713, 8806, 8840-8842, 8921, 8982, 8990, 9373 C000-C809 069
(e) Unspecified soft tissue sarcomas 8800-8805 C000-C399, C440-C768, C809 070
X. Germ cell tumors, trophoblastic tumors, and neoplasms of gonads
(a) Intracranial and intraspinal germ cell tumors
(a.1) Intracranial and intraspinal germinomas 9060-9065 C700-C729, C751-C753 071
(a.2) Intracranial and intraspinal teratomas 9080-9084 C700-C729, C751-C753 072
(a.3) Intracranial and intraspinal embryonal carcinomas 9070, 9072 C700-C729, C751-C753 073
(a.4) Intracranial and intraspinal yolk sac tumor 9071 C700-C729, C751-C753 074
(a.5) Intracranial and intraspinal choriocarcinoma 9100 C700-C729, C751-C753 075
(a.6) Intracranial and intraspinal tumors of mixed forms 9085, 9101 C700-C729, C751-C753 076
(b) Malignant extracranial and extragonadal germ cell tumors
(b.1) Malignant germinomas of extracranial and extragonadal sites 9060-9065 C000-C559, C570-C619, C630-C699, C739-C750, C754-C768, C809 077
(b.2) Malignant teratomas of extracranial and extragonadal sites 9080-9084 C000-C559, C570-C619, C630-C699, C739-C750, C754-C768, C809 078
(b.3) Embryonal carcinomas of extracranial and extragonadal sites 9070, 9072 C000-C559, C570-C619, C630-C699, C739-C750, C754-C768, C809 079
(b.4) Yolk sac tumor of extracranial and extragonadal sites 9071 C000-C559, C570-C619, C630-C699, C739-C750, C754-C768, C809 080
(b.5) Choriocarcinomas of extracranial and extragonadal sites 9100, 9103, 9104 C000-C559, C570-C619, C630-C699, C739-C750, C754-C768, C809 081
(b.6) Other and unspecified malignant mixed germ cell tumors of extracranial and extragonadal sites 9085, 9101, 9102, 9105 C000-C559, C570-C619, C630-C699, C739-C750, C754-C768, C809 082
(c) Malignant gonadal germ cell tumors
(c.1) Malignant gonadal germinomas 9060-9065 C569, C620-C629 083
(c.2) Malignant gonadal teratomas 9080-9084, 9090, 9091 C569, C620-C629 084
(c.3) Gonadal embryonal carcinomas 9070, 9072 C569, C620-C629 085
(c.4) Gonadal yolk sac tumor 9071 C569, C620-C629 086
(c.5) Gonadal choriocarcinoma 9100 C569, C620-C629 087
(c.6) Malignant gonadal tumors of mixed forms 9085, 9101 C569, C620-C629 088
(c.7) Malignant gonadal gonadoblastoma 9073 C569, C620-C629 089
(d) Gonadal carcinomas 8010-8041, 8050-8075, 8082, 8120-8122, 8130-8141, 8143, 8190-8201, 8210, 8211, 8221-8241, 8244-8246, 8260-8263, 8290, 8310, 8313, 8320, 8323, 8380-8384, 8430, 8440, 8480-8490, 8504, 8510, 8550, 8560-8573, 9000, 9014, 9015 C569, C620-C629 090
8441-8444, 8450, 8451, 8460-8473 C000-C809 090
(e) Other and unspecified malignant gonadal tumors 8590-8671 C000-C809 091
8000-8005 C569, C620-C629 091
XI. Other malignant epithelial neoplasms and malignant melanomas
(a) Adrenocortical carcinomas 8370-8375 C000-C809 092
(b) Thyroid carcinomas 8010-8041, 8050-8075, 8082, 8120-8122, 8130-8141, 8190, 8200, 8201, 8211, 8230, 8231, 8244-8246, 8260-8263, 8290, 8310, 8320, 8323, 8430, 8440, 8480, 8481, 8510, 8560-8573 C739 093
8330-8337, 8340-8347, 8350 C000-C809 093
(c) Nasopharyngeal carcinomas 8010-8041, 8050-8075, 8082, 8083, 8120-8122, 8130-8141, 8190, 8200, 8201, 8211, 8230, 8231, 8244-8246, 8260-8263, 8290, 8310, 8320, 8323, 8430, 8440, 8480, 8481, 8500-8576 C110-C119 094
(d) Malignant melanomas 8720-8780, 8790 C000-C809 095
(e) Skin carcinomas 8010-8041, 8050-8075, 8078, 8082, 8090-8110, 8140, 8143, 8147, 8190, 8200, 8240, 8246, 8247, 8260, 8310, 8320, 8323, 8390-8420, 8430, 8480, 8542, 8560, 8570-8573, 8940, 8941 C440-C449 096
(f) Other and unspecified carcinomas
(f.1) Carcinomas of salivary glands 8010-8084, 8120-8157, 8190-8264, 8290, 8310, 8313-8315, 8320-8325, 8360, 8380-8384, 8430-8440, 8452-8454, 8480-8586, 8588-8589, 8940, 8941, 8983, 9000, 9010-9016, 9020, 9030 C079-C089 097
(f.2) Carcinomas of colon and rectum 8010-8084, 8120-8157, 8190-8264, 8290, 8310, 8313-8315, 8320-8325, 8360, 8380-8384, 8430-8440, 8452-8454, 8480-8586, 8588-8589, 8940, 8941, 8983, 9000, 9010-9016, 9020, 9030 C180, C182-C189, C199, C209, C210-C218 098
(f.3) Carcinomas of appendix 8010-8084, 8120-8157, 8190-8264, 8290, 8310, 8313-8315, 8320-8325, 8360, 8380-8384, 8430-8440, 8452-8454, 8480-8586, 8588-8589, 8940, 8941, 8983, 9000, 9010-9016, 9020, 9030 C181 099
(f.4) Carcinomas of lung 8010-8084, 8120-8157, 8190-8264, 8290, 8310, 8313-8315, 8320-8325, 8360, 8380-8384, 8430-8440, 8452-8454, 8480-8586, 8588-8589, 8940, 8941, 8983, 9000, 9010-9016, 9020, 9030 C340-C349 100
(f.5) Carcinomas of thymus 8010-8084, 8120-8157, 8190-8264, 8290, 8310, 8313-8315, 8320-8325, 8360, 8380-8384, 8430-8440, 8452-8454, 8480-8586, 8588-8589, 8940, 8941, 8983, 9000, 9010-9016, 9020, 9030 C379 101
(f.6) Carcinomas of breast 8010-8084, 8120-8157, 8190-8264, 8290, 8310, 8313-8315, 8320-8325, 8360, 8380-8384, 8430-8440, 8452-8454, 8480-8586, 8588-8589, 8940, 8941, 8983, 9000, 9010-9016, 9020, 9030 C500-C509 102
(f.7) Carcinomas of cervix uteri 8010-8084, 8120-8157, 8190-8264, 8290, 8310, 8313-8315, 8320-8325, 8360, 8380-8384, 8430-8440, 8452-8454, 8480-8586, 8588-8589, 8940, 8941, 8983, 9000, 9010-9016, 9020, 9030 C530-C539 103
(f.8) Carcinomas of bladder 8010-8084, 8120-8157, 8190-8264, 8290, 8310, 8313-8315, 8320-8325, 8360, 8380-8384, 8430-8440, 8452-8454, 8480-8586, 8588-8589, 8940, 8941, 8983, 9000, 9010-9016, 9020, 9030 C670-C679 104
(f.9) Carcinomas of eye 8010-8084, 8120-8157, 8190-8264, 8290, 8310, 8313-8315, 8320-8325, 8360, 8380-8384, 8430-8440, 8452-8454, 8480-8586, 8588-8589, 8940, 8941, 8983, 9000, 9010-9016, 9020, 9030 C690-C699 105
(f.10) Carcinomas of other specified sites 8010-8084, 8120-8157, 8190-8264, 8290, 8310, 8313-8315, 8320-8325, 8360, 8380-8384, 8430-8440, 8452-8454, 8480-8586, 8588-8589, 8940, 8941, 8983, 9000, 9010-9016, 9020, 9030 C000-C069, C090-C109, C129-C179, C239-C339, C380-C399, C480-C488, C510-C529, C540-C549, C559, C570-C619, C630-C639, C659-C669, C680-C689, C700-C729, C750-C759 106
(f.11) Carcinomas of unspecified site 8010-8084, 8120-8157, 8190-8264, 8290, 8310, 8313-8315, 8320-8325, 8360, 8380-8384, 8430-8440, 8452-8454, 8480-8586, 8588-8589, 8940, 8941, 8983, 9000, 9010-9016, 9020, 9030 C760-C768, C809 107
XII. Other and unspecified malignant neoplasms
(a) Other specified malignant tumors
(a.1) Gastrointestinal stromal tumor 8936 C000-C809 108
(a.2) Pancreatoblastoma 8971 C000-C809 109
(a.3) Pulmonary blastoma and pleuropulmonary blastoma 8972, 8973 C000-C809 110
(a.4) Other complex mixed and stromal neoplasms 8930-8935, 8950, 8951, 8974-8981 C000-C809 111
(a.5) Mesothelioma 9050-9055 C000-C809 112
(a.6) Other specified malignant tumors 9110 C000-C809 113
9363 C000-C399, C470-C759 113
(b) Other unspecified malignant tumors 8000-8005 C000-C218, C239-C399, C420-C559, C570-C619, C630-C639, C659-C699, C739-C750, C754-809 114

*. Steliarova-Foucher E, Stiller C, Lacour B, Kaatsch P. International Classification of Childhood Cancer, Third Edition. Cancer 2005;103:1457-67.