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HCPCS (Descending) Generic Name Brand Name Strength SEER*Rx Category Major Drug Class Minor Drug Class Oral (Y/N) FDA Approval Year FDA Discontinuation Year CMS Effective Date CMS Discontinuation Date Status
J9271 Pembrolizumab Keytruda 1 mg Immunotherapy Checkpoint Inhibitor PD-1 No 2014 Jan. 1, 2016 In Use
J9270 Plicamycin Plicamycin 2.5 mg Chemotherapy Antitumor Antibiotic Anthracycline No 1970 2000 Jan. 1, 1984 In Use
J9269 Tagraxofusp-erzs Elzonris 10mcg Immunotherapy Recombinant Fusion Protein IL3/CD123 No 2018 Oct. 1, 2019 In Use
J9268 Pentostatin Nipent 10 mg Chemotherapy Antimetabolite Purine Analog No 1991 Jan. 1, 1994 In Use
J9267 Paclitaxel Taxol 1 mg Chemotherapy Antimitotic Agent Taxane No 1992 Jan. 1, 2015 In Use
J9266 Pegaspargase Oncaspar unspecified Chemotherapy Miscellaneous Agent Enzyme No 1994 Jan. 1, 1996 In Use
J9265 Paclitaxel Taxol 30 mg Chemotherapy Antimitotic Agent Taxane No 1992 Jan. 1, 1994 Dec. 31, 2014 No Longer Used
J9264 Paclitaxel Abraxane, protein bound 1 mg Chemotherapy Antimitotic Agent Taxane No 1992 Jan. 1, 2006 In Use
J9263 Oxaliplatin Eloxatin 0.5 mg Chemotherapy Alkylating Agent Platinum Compound No 2002 Jan. 1, 2004 In Use
J9262 Omacetaxine Synribo 0.01 mg Chemotherapy Plant Alkaloid BCR-ABL No 2012 Jan. 1, 2014 In Use
J9261 Nelarabine Arranon 50 mg Chemotherapy Antimetabolite Purine Analog No 2005 Jan. 1, 2007 In Use
J9260 Methotrexate Trexall 50 mg Chemotherapy Antimetabolite Folic Acid Analog No 1953 Jan. 1, 1984 In Use
J9259 Paclitaxel (American Regent) Paclitaxel (American Regent) 1mg Chemotherapy Antimitotic Agent Taxane No 2023 July 11, 2023 In Use
J9250 Methotrexate Trexall 5 mg Chemotherapy Antimetabolite Folic Acid Analog Yes 1953 Jan. 1, 1994 In Use
J9247 Melphalan flufenamide Pepaxto 1mg Chemotherapy Alkylating Agent Nitrogen Mustard No 2021 Sept. 27, 2021 In Use
J9246 Melphalan Evomela 1mg Chemotherapy Alkylating Agent Nitrogen Mustard No 2016 July 1, 2020 In Use
J9245 Melphalan Melphalan 50 mg Chemotherapy Alkylating Agent Nitrogen Mustard No 1992 Jan. 1, 1995 In Use
J9230 Mechlorethamine Mustargen 10 mg Chemotherapy Alkylating Agent Nitrogen Mustard No 1949 Jan. 1, 1986 In Use
J9228 Ipilimumab Yervoy 1mg Immunotherapy Checkpoint Inhibitor CTLA-4 No 2011 Jan. 1, 2012 In Use
J9227 Isatuximab-irtc Sarclisa 10mg Immunotherapy Monoclonal Antibody CD38 No 2020 Oct. 1, 2020 In Use
J9226 Histrelin Acetate Supprelin LA 50 mg Hormonal Therapy GnRH Agonist No 2004 Jan. 1, 2008 In Use
J9225 Histrelin Acetate Vantas 50 mg Hormonal Therapy GnRH Agonist No 2004 Jan. 1, 2008 In Use
J9223 Lurbinectedin Zepzelca 0.1mg Chemotherapy Alkylating Agent Adduct Forming Agent No 2020 Jan. 1, 2021 In Use
J9219 Leuprolide Acetate Implant Viadur 65 mg Hormonal Therapy GnRH Agonist No 2000 Jan. 1, 2016 In Use
J9218 Leuprolide Acetate Eligard, Lupron Depot, Viadur, Lupron 1 mg Hormonal Therapy GnRH Agonist No 1995 Jan. 1, 1997 In Use

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The use of NA indicates that the HCPCS code was Not Available. NA may mean that a) the HCPCS code has not yet been created (new drug), b) the drug is given as an oral drug or alternative route (only in specific instances are HCPCS assigned to these medications), or c) the HCPCS could not be found or is truly not available.