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HCPCS Generic Name Brand Name Strength SEER*Rx Category Major Drug Class Minor Drug Class (Ascending) Oral (Y/N) FDA Approval Year FDA Discontinuation Year CMS Effective Date CMS Discontinuation Date Status
J9080 Cyclophosphamide Cyclophosphamide 200 mg Chemotherapy Alkylating Agent Nitrogen Mustard No 1959 Jan. 1, 1994 Dec. 31, 2010 No Longer Used
J9090 Cyclophosphamide Cyclophosphamide 500 mg Chemotherapy Alkylating Agent Nitrogen Mustard No 1959 Jan. 1, 1994 Dec. 31, 2010 No Longer Used
C9420 Cyclophosphamide Cyclophosphamide 100 mg Chemotherapy Alkylating Agent Nitrogen Mustard No 1959 Jan. 1, 2004 Dec. 31, 2005 No Longer Used
C9421 Cyclophosphamide Cyclophosphamide lyophilized 100 mg Chemotherapy Alkylating Agent Nitrogen Mustard No 1959 Jan. 1, 2004 Dec. 31, 2005 No Longer Used
J9093 Cyclophosphamide Cyclophosphamide lyophilized 100 mg Chemotherapy Alkylating Agent Nitrogen Mustard No 1959 Jan. 1, 1988 Dec. 31, 2010 No Longer Used
J9094 Cyclophosphamide Cyclophosphamide lyophilized 200 mg Chemotherapy Alkylating Agent Nitrogen Mustard No 1959 Jan. 1, 1994 In Use
J9095 Cyclophosphamide Cyclophosphamide lyophilized 500 mg Chemotherapy Alkylating Agent Nitrogen Mustard No 1959 Jan. 1, 1994 Dec. 31, 2010 No Longer Used
J9096 Cyclophosphamide Cyclophosphamide lyophilized 1 g Chemotherapy Alkylating Agent Nitrogen Mustard No 1959 Jan. 1, 1994 Dec. 31, 2010 No Longer Used
J9097 Cyclophosphamide Cyclophosphamide lyophilized 2 g Chemotherapy Alkylating Agent Nitrogen Mustard No 1959 Jan. 1, 1994 In Use
NA Cyclophosphamide Cyclophosphamide oral 50 mg Chemotherapy Alkylating Agent Nitrogen Mustard Yes 1959 In Use
J8530 Cyclophosphamide Cyclophosphamide oral 25 mg Chemotherapy Alkylating Agent Nitrogen Mustard Yes 1959 Jan. 1, 1995 In Use
NA Estramustine Phosphate Sodium Emcyt 140 mg Chemotherapy Alkylating Agent Nitrogen Mustard Yes 1981 In Use
C9427 Ifosfamide ifex 1 g Chemotherapy Alkylating Agent Nitrogen Mustard No 1988 Jan. 1, 2004 Dec. 31, 2005 No Longer Used
J9208 Ifosfamide Ifosfamide 1 g Chemotherapy Alkylating Agent Nitrogen Mustard No 1988 Jan. 1, 1999 In Use
J9230 Mechlorethamine Mustargen 10 mg Chemotherapy Alkylating Agent Nitrogen Mustard No 1949 Jan. 1, 1986 In Use
J9245 Melphalan Melphalan 50 mg Chemotherapy Alkylating Agent Nitrogen Mustard No 1992 Jan. 1, 1995 In Use
J8600 Melphalan Melphalan, Alkeran 2 mg Chemotherapy Alkylating Agent Nitrogen Mustard Yes 1992 Jan. 1, 1995 In Use
NA Uracil Mustard Uramustine unspecified Chemotherapy Alkylating Agent Nitrogen Mustard No 1962 1999 No Longer Used
J9036 Bendamustine HCL Belrapzo 1mg Chemotherapy Alkylating Agent Nitrogen Mustard No 2018 July 1, 2019 In Use
J9246 Melphalan Evomela 1mg Chemotherapy Alkylating Agent Nitrogen Mustard No 2016 July 1, 2020 In Use
C9080 Melphalan flufenamide Pepaxto 1mg Chemotherapy Alkylating Agent Nitrogen Mustard No 2021 July 23, 2021 Sept. 27, 2021 No Longer Used
J9247 Melphalan flufenamide Pepaxto 1mg Chemotherapy Alkylating Agent Nitrogen Mustard No 2021 Sept. 27, 2021 In Use
C9087 Cyclophosphamide (Auromedics) Cyclophosphamide 10mg Chemotherapy Alkylating Agent Nitrogen Mustard No 2021 Jan. 26, 2022 March 25, 2022 In Use
J9056 Bendamustine Vivimusta 1mg Chemotherapy Alkylating Agent Nitrogen Mustard No 2022 July 11, 2023 In Use
J9058 Bendamustine (Apotex) Bendamustine (Apotex) 1mg Chemotherapy Alkylating Agent Nitrogen Mustard No 2023 July 11, 2023 In Use

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The use of NA indicates that the HCPCS code was Not Available. NA may mean that a) the HCPCS code has not yet been created (new drug), b) the drug is given as an oral drug or alternative route (only in specific instances are HCPCS assigned to these medications), or c) the HCPCS could not be found or is truly not available.