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SEER Inquiry System - Report
Produced: 01/04/2026 9:44 AM
Question 20010022
Inquiry Details
References:
#1: SEER Program Code Man, 3rd Ed, 102
#2: 2004 SEER Manual, 93, C-598
Question:
Grade, Differentiation--Bladder: Some pathologists use a two component grade system for bladder carcinomas - either low grade or high grade. Should we continue to code these per SEER rules as grades 2 [low grade] and 4 [high grade]? See discussion.
Discussion:
The AFIP website states that this low grade classification corresponds to grade 1/3, while the high grade corresponds to both grade 2/3 and grade 3/3. Using the 3-grade conversion, this would also classify the low grade as grade 2, but would leave the high grade as a toss-up between grade 3 and grade 4.
Answer:
Continue to code Grade, Differentiation as specified in the SEER Program Code Manual: "Low grade" is coded to 2 and "high grade" is coded to 4.
Cancer Site Category:
Bladder
Data Item Category:
N/A
Other Category:
N/A
Year:
2001
