SEER Inquiry System - Question 20021029 Details

System Guide

Back to Search Results

SEER Inquiry System - Report

Produced: 10/27/2025 8:34 PM

Question 20021029

Export CSV Export PDF Print

Add to Report

Inquiry Details

References:

SEER Program Code Man, 3rd Ed, 103

Question:

Grade, Differentiation--Breast: Should the Bloom-Richardson (BR) grade (low, intermediate, high) have a higher priority than terminology (i.e., well differentiated)? See discussion.

Discussion:

1. Grade of infiltrating carcinoma 1) Nuclear grade low; 2) Histological grade-intermediate; 3) Mitotic rate-low, 4) BR score 4.

2. Poorly differentiated but grade II/III. Microscopic comment: Slides show infiltrating ca which is P.D. in that it forms no tubules, but is grade 2 out of 3 in the modified BR scheme. It is ductal type with large moderately pleomorphic tumor cells displaying few mitoses.

3. Invasive moderately differentiated duct cell carcinoma with the following features: Modified BR grade: III/III (2+3+3=8).

Answer:

For cases diagnosed prior to 2004:

Code the example cases as follows:

1. Grade 2. Histologic grade terminology ("intermediate") has the highest priority.

2. Grade 3. Terminology ("poorly differentiated") has the highest priority.

3. Grade 2. Histologic grade terminology "moderately differentiated" has priority.

Cancer Site Category:

Breast

Data Item Category:

N/A

Other Category:

N/A

Year:

2002