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SEER Inquiry System - Report
Produced: 11/26/2024 9:20 PM
Question 20110068
Inquiry Details
References:
2010 SEER Manual. Appendix C
Question:
Discussion:
A patient has papillary transitional cell carcinoma of the bladder in March of 2009. In June of 2010 the patient has another TURBT that demonstrates a flat in situ and invasive high grade urothelial carcinoma. The path addendum indicates, "Genzyme IHC show results consistent with high grade invasive urothelial carcinoma with neuroendocrine features." Two months later a liver biopsy shows poorly differentiated malignant tumor. The path addendum indicates, "Genzyme IHC results show metastatic poorly differentiated carcinoma with neuroendocrine features, favor bladder primary."
Is the latter a second bladder primary with histology code 8246/3 [neuroendocrine carcinoma]?
NOTE: Neuroendocrine is not listed as an urothelial tumor in Table 1 of MP/H Rules.
Answer:
Use the Multiple Primary and Histology Coding Rules Manual for cases diagnosed 2007 or later to determine the number of primaries. This is a single primary. The 2010 diagnosis is urothelial carcinoma. The presence of "neuroendocrine features" does not change the histologic category.
The steps used to arrive at this decision are:
Open the Multiple Primary and Histology Coding Rules manual. Once in the manual, locate the Urinary MP rules under one of the three formats (i.e., flowchart, matrix or text). The rules are intended to be reviewed in consecutive order within the module. You stop at the first rule that applies to the case you are processing.
Start at the MULTIPLE TUMORS module start at rule M3.
. Bladder tumors with any combination of transitional cell carcinoma and papillary transitional carcinoma are a single primary.
