SEER Inquiry System - Question 20180010 Details

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SEER Inquiry System - Report

Produced: 10/29/2025 4:36 AM

Question 20180010

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Inquiry Details

References:

Heme & Lymph Manual & DB

Question:

Diagnostic confirmation--Heme & Lymphoid Neoplasms: Is Diagnostic Confirmation coded as 5 (positive laboratory test/ marker study) or code 8 (clinical diagnosis only) for a case that has a positive JAK2 mutation, and based on the results of the JAK2, the physician diagnosed the patient with polycythemia vera? There were no blood smears or bone marrow biopsies done.

Discussion:

Answer:

Assign diagnostic confirmation code 5 for a positive laboratory test/marker study. A note was added to the Hematopoietic manual to state that code 5 now includes cases with no histological confirmation but there is positive immunophenotyping or genetic studies.

History:

Prior to Oct 2018: Assign diagnostic confirmation code 8 for a clinical diagnosis only. Code 5 is not correct in this case because JAK2 is not definitive for any specific hematopoietic neoplasm. The physician uses JAK2 info combined with all of the other facts for the case to make the diagnosis.

Cancer Site Category:

Heme & Lymphoid Neoplasms

Data Item Category:

Diagnostic confirmation

Other Category:

N/A

Year:

2018