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SEER Inquiry System - Report
Produced: 10/20/2025 1:21 AM
Question 20220029
Inquiry Details
References:
#1: WHO Class Digest System Tumors. 5th edition
#2: Subject matter expert
Question:
Histology/Behavior--GI Tract: What is the difference between high grade dysplasia and severe dysplasia for tumors in the cervix and gastrointestinal (GI) tract? Are these terms synonymous with in situ/behavior code /2? See Discussion.
Discussion:
In the WHO Classification of Female Genital Tumors, 5th edition, for the uterine cervix squamous intraepithelial lesions, there is related terminology for high grade squamous intraepithelial lesion HSIL (CIN3) 8077/2 and it is severe squamous dysplasia; squamous cell in situ. However, in the online WHO Classification of Digestive System Tumors, 5th edition, there is no related terminology for esophageal high-grade squamous dysplasia, 8077/2. Can you collect cases of severe dysplasia the same as cases of high grade dysplasia?
Answer:
According to a leading GI pathologist, severe dysplasia is equivalent to high grade dysplasia in the GI tract.
