Name

CA-125

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Definition

A substance that may be found in high amounts in the blood of patients with certain types of cancer, including ovarian cancer. CA-125 levels may also help monitor how well cancer treatments are working or if cancer has come back.

Resource

Title: National Cancer Institute
NCI Dictionary of Cancer Terms

Alternate Names

Cancer antigen 125
Carbohydrate antigen 125

Abstractor Notes

High levels of CA-125 aren't always due to cancer. Other conditions that may cause higher levels of CA-125 include: uterine fibroids, endometriosis, lupus, liver disease, pancreatitis, pelvic inflammatory disease (PID), the first trimester of a pregnancy, menstruation.

In addition, recent abdominal surgery or radioactive scans can alter CA-125 levels.

Histology

None

Primary Sites

None
Glossary