Name

Layers of the skin

This definition applies to

All SEER websites where this term appears

Definition

There are several different layers of the skin

1. Epidermis: The outer layer of the two main layers of the skin. It is composed of stratified squamous epithelium. It has several layers. The cells of each of these layer's change as they move from the basal layer up to the surface of the skin. The primary cells found in the outer layer of the epidermis are keratinocytes.
Stratum corneum: The outermost layer of epidermis, consisting of dead cells.
Stratum germinativum: The lowermost layer, the regenerative layer of the epidermis.
Stratum granulosoma: Made of flattened cells containing granules.
Stratum lucidum: Clear layer of epidermis
Stratum spinosum: Spiny or prickly layer of epidermis

2. Dermis: The inner layer of the two main layers of the skin. The dermis has connective tissue, blood vessels, oil and sweat glands, nerves, hair follicles, and other structures. It is made up of a thin upper layer called the papillary dermis, and a thick lower layer called the reticular dermis.

3. Papillary dermis: The thin top layer of the dermis (the inner layer of the skin). The papillary dermis has connective tissue and blood vessels that give nutrients to the epidermis (the outer layer of the skin) and that help control the temperature of the skin.

4. Papillary-reticular dermal interface: Layer of skin between the papillary dermis and the reticular dermis.

5. Reticular dermis: The thick bottom layer of the dermis (the inner layer of the skin). The reticular dermis has blood vessels and connective tissue that supports the skin. Hair follicles, oil and sweat glands, and other structures are also found in the reticular dermis.

6. Hypodermis (Subcutis): Loose subcutaneous or connective tissue that is found beneath the skin. Bursae is also found beneath the skin, along with a subcutaneous reservoir in which fluid is stored.

7. Deep fascia: Sheets of dense, fibrous tissue holding muscle groups together below the hypodermis layer or subcutaneous fat layer that lines the extremities and trunk.

Resource

Title: SEER Self Instructional Manuals for Tumor Registrars
Edition: Book 4
Year: 1995
Human Anatomy as Related to Tumor Formation

Alternate Names

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Abstractor Notes

The different layers of the skin (dermis, epidermis, papillary dermis, papillary-reticular dermal interface, reticular dermis, and hypodermis (subcutaneous tissue) are important for Melanoma Skin Summary Stage.

See also Clark Level

Histology

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Primary Sites

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Glossary