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Name

ERRC genes (2 and 3)

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Definition

Genes that make a protein involved in the first step of making proteins and in repairing damaged DNA. Mutations (changes) in the ERCC1 and ERCC2 genes may cause cells to lose their ability to repair damaged DNA, which may lead to abnormal cell growth. ERCC1 and ERCC2 gene mutations have been found in several inherited syndromes, including a condition called xeroderma pigmentosum. People with these conditions have a very high risk of developing skin cancer and other types of cancer.

Resource

Title: National Cancer Institute
NCI Dictionary of Cancer Terms

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