Name

Precursor cell lymphoblastic leukemia, NOS (see 9811/3 for 2010-2025)

ICD-O-3 Morphology

9835/3: Precursor cell lymphoblastic leukemia, NOS
Effective 2001 and later

Reportable

2001-2009, 2026 and later; see Abstractor Notes

Primary Site(s)

C421

Abstractor Notes

This code may be used for cases diagnosed prior to 1/1/2010, and 2026. See 9811/3 for years 2010-2025.

Because of advances in the field of molecular biology, neoplasms that were called "precursor" are now identified as specific neoplasms with genetic or CD abnormalities. This code and code description is not included in the 2008 WHO classification of hematopoietic and lymphoid neoplasms. Those leukemias previously coded to this classification have now been reclassified by their genetic or cell antigen abnormalities.

This code may be used for DCO cases or those cases with minimal information. For further information on the coding and abstracting of this neoplasm, see histology codes 9811.

Diagnostic Confirmation

None

Module Rule

None

Alternate Names

Acute lymphatic leukemia (see 9811/3 for 2010-2025)
Acute lymphoblastic leukemia, FAB L2, type, NOS [OBS] (see 9811/3 for 2010-2025)
Acute lymphoblastic leukemia, NOS (see 9811/3 for 2010-2025)
Acute lymphoblastic leukemia, precursor-cell type (see 9811/3 for 2010-2025)
Acute lymphoblastic leukemia-lymphoma, NOS (see 9811/3 for 2010-2025)
Acute lymphocytic leukemia (see 9811/3 for 2010-2025)
Acute lymphoid leukemia (see 9811/3 for 2010-2025)
FAB L1 [OBS] (see 9811/3 for 2010-2025)
FAB L2 [OBS] (see 9811/3 for 2010-2025)
Lymphoblastic leukemia (see 9811/3 for 2010-2025)
Lymphoblastic leukemia/lymphoma (see 9811/3 for 2010-2025)
NK-lymphoblastic leukemia lymphoma
Precursor cell lymphoblastic leukemia, not phenotyped (see 9811/3 for 2010-2025)
Precursor cell lymphoblastic lymphoma, NOS (see 9811/3 for 2010-2026)

Definition

In the past, ALL lymphoblasts were classified using the FAB criteria as having L1, L2 or L3 morphology. Because of the lack of independent prognostic significance and the subjective nature of this classification system, it is no longer used. Precursor ALL is either B-cell or T-cell.

Definitive Diagnostic Methods

None

Genetics Data

None

Immunophenotyping

None

Treatments

Chemotherapy
Hematologic Transplant and/or Endocrine Procedures
Hormone therapy
Radiation therapy

Transformations to

There are no known transformations

Transformations from

There are no known transformations

Corresponding ICD-10 Codes (Cause of Death codes only)

C91.0 Acute lymphoblastic leukemia

Corresponding ICD-10-CM Codes (U.S. only)

C91.0 Acute lymphoblastic leukemia [ALL] (effective October 01, 2015)

Signs and Symptoms

None

Diagnostic Exams

None

Progression and Transformation

None

Epidemiology and Mortality

None

Sources

International Classification of Diseases for Oncology, 3rd edition (including revisions). Geneva: World Health Organization, 2001, 2011, 2020.
Section: ICD-O-3.2 (2020) Morphological Codes
Pages: http://www.iacr.com.fr/index.php?option=com_content&view=category&layout=blog&id=100&Itemid=577
Glossary