Eribulin |
Chemotherapy
|
GYN,
Metastatic breast,
NSCLC,
Pancreas,
prostate,
urinary sites,
Soft tisse
|
Yes
|
Combretastatin A4 Prodrug |
Chemotherapy
|
Colon,
head & neck,
lung,
other cancer,
thyroid
|
Yes
|
Istodax |
Chemotherapy
|
H&N,
Lung cancer,
lymphoma,
soft tissue sarcoma,
T cell lymphoma,
thyroid
|
Yes
|
Sorafenib |
Chemotherapy
|
Kidney,
Leukemia,
colon,
liver,
lymphoma,
other cancer,
prostate,
thyroid
|
Yes
|
Lenvima |
Chemotherapy
|
Lung,
liver,
lymphoma,
thyroid
|
Yes
|
Axitinib |
Chemotherapy
|
Colorectal,
kidney,
melanoma,
pancreas,
thyroid
|
Yes
|
Etoposide |
Chemotherapy
|
Gastric cancer,
Hodgkins lymphoma,
Lung cancer (NSCLC, SCLC),
Non-Hodgkin lymphoma,
testicular cancer (Germ cell tumors)
|
Yes
|
Dactinomycin |
Chemotherapy
|
Ewing's sarcoma,
rhabdomyosarcoma,
testicular cancer,
Wilm's tumor
|
Yes
|
Cisplatin |
Chemotherapy
|
Bladder,
ovarian,
testicular cancer
|
Yes
|
Imiquimod |
Biologic therapy (BRM, immunotherapy)
|
Cervical cancer,
melanoma,
superficial basal cell carcinoma
|
Yes
|
GDC-0449 |
Chemotherapy
|
brain/cns,
colorectal,
GE,
lung,
ovarian,
Pancreas,
stomach
|
Yes
|
Lovastatin |
Chemotherapy
|
AML,
Hepatoma,
stomach
|
Yes
|
Sunitinib maleate |
Chemotherapy
|
breast,
GIST,
pancreas,
Renal cell,
stomach,
Urothelial ca
|
Yes
|
Paclitaxel poliglumex |
Chemotherapy
|
breast,
esophagus,
NSCLC,
ovary,
Prostate,
stomach
|
Yes
|
MK-5108 |
Chemotherapy
|
solid tumors
|
Yes
|
Terameprocol |
Chemotherapy
|
Gliomas,
solid tumors
|
Yes
|
Tivantinib |
Chemotherapy
|
hepatocellular,
lung,
solid tumors
|
Yes
|
STA-9090 |
Chemotherapy
|
GIST,
Leukemia,
MDS,
solid tumors
|
Yes
|
XL-184 |
Chemotherapy
|
GBM,
NSCLC,
solid tumors,
Thyroid
|
Yes
|
R04929097 |
Chemotherapy
|
advanced breast,
NSCLC,
pediatric neuroblastoma,
solid tumors
|
Yes
|
Carubicin (HCl) |
Chemotherapy
|
Leukemia,
lymphoma,
solid tumors
|
Yes
|
IPI-504 |
Chemotherapy
|
breast,
GIST,
lung,
melanoma,
Myeloma,
prostate,
soft tissue,
solid tumor
|
Yes
|
Cyclophosphamide |
Chemotherapy
|
Breast,
leukemia,
lymphoma,
multiple myeloma,
neuroblastoma,
ovarian cancer,
retinoblastoma,
soft tissue sarcoma,
Wilm's tumor
|
Yes
|
Trabectedin |
Chemotherapy
|
Breast,
Ewing's family of tumors,
endometrial,
leiomyosarcoma,
melanoma,
other,
ovarian cancer,
sarcoma,
soft tissue sarcoma
|
Yes
|
Soblidotin |
Chemotherapy
|
Lung,
soft tissue
|
Yes
|
Flavopiridol |
Chemotherapy
|
B-cell CLL,
Colorectal,
lung,
other cancer,
prolymphocytic leukemia arising from CLL,
small lymphocytic lymphoma
|
Yes
|
Topotecan |
Chemotherapy
|
cervix,
Colorectal,
leukemia,
lung,
ovarian cancer,
small cell lung
|
Yes
|
Picoplatin |
Chemotherapy
|
breast,
ovarian,
Prostate,
small cell lung
|
Yes
|
Thymosin alpha 1 |
Biologic therapy (BRM, immunotherapy)
|
Breast,
liver,
skin cancer
|
Yes
|
IM862 |
Chemotherapy
|
Breast,
colorectal,
kidney,
ovarian,
prostate,
sarcoma,
skin cancer
|
Yes
|
Decitabine |
Chemotherapy
|
CML,
Leukemia,
lung,
MDS,
skin cancer
|
Yes
|
Poly I: Poly C12U |
Biologic therapy (BRM, immunotherapy)
|
Kidney,
skin cancer
|
Yes
|
ProMune |
Biologic therapy (BRM, immunotherapy)
|
basal cell,
Breast,
kidney,
lung,
lymphoma,
melanoma,
NHL,
skin cancer
|
Yes
|
FLT3 Ligand |
Biologic therapy (BRM, immunotherapy)
|
Leukemia,
skin cancer
|
Yes
|
DENSPM |
Chemotherapy
|
Breast,
colorectal,
kidney,
leukemia,
lung,
ovarian,
pancreatic,
skin cancer
|
Yes
|
IMC-1c111 |
Chemotherapy
|
Colorectal,
skin cancer
|
Yes
|
Metastat |
Chemotherapy
|
Brain,
sarcoma,
skin cancer
|
Yes
|
Leuvectin |
Biologic therapy (BRM, immunotherapy)
|
Kidney,
prostate,
skin cancer
|
Yes
|
Cancer Vaccine |
Biologic therapy (BRM, immunotherapy)
|
Bladder,
breast,
kidney,
ovarian,
skin cancer
|
Yes
|
Thalidomide |
Biologic therapy (BRM, immunotherapy)
|
Brain,
kidney,
leukemia,
liver,
lung,
lymphoma,
multiple myeloma,
prostate,
skin cancer
|
Yes
|
Troxacitabine |
Chemotherapy
|
acute myelogenous leukemia,
Breast,
colorectal,
kidney,
lung,
ovarian,
pancreatic,
prostate,
skin cancer
|
Yes
|
Eflornithine |
Chemotherapy
|
Bladder,
brain (glioblastoma),
childhood leukemia,
CML,
skin cancer
|
Yes
|
T904064 |
Chemotherapy
|
Breast,
head & neck,
lung,
sarcoma,
skin cancer
|
Yes
|
Alitretinoin |
Differentiation inducing agent
|
Breast,
Kaposi sarcoma,
leukemia,
sarcoma,
skin cancer
|
No
|
O-6-Benzylguanine |
Chemotherapy
|
Brain,
colorectal,
multiple myeloma,
sarcoma,
skin cancer
|
Yes
|
Canvaxin |
Biologic therapy (BRM, immunotherapy)
|
Colorectal,
skin cancer
|
Yes
|
Taxoprexin |
Chemotherapy
|
Breast,
colorectal,
gastric,
kidney,
lung,
pancreatic,
prostate,
skin cancer
|
Yes
|
CpG 7909 |
Biologic therapy (BRM, immunotherapy)
|
Breast,
kidney cancer,
melanoma,
non-Hodgkin's' lymphoma,
skin cancer
|
Yes
|
Oncophage |
Biologic therapy (BRM, immunotherapy)
|
Colorectal,
gastric,
kidney,
lymphoma,
pancreatic,
sarcoma,
skin cancer
|
Yes
|
SB249553 |
Biologic therapy (BRM, immunotherapy)
|
Lung,
melanoma,
skin cancer
|
Yes
|
Amifostine |
Ancillary Agent
|
Breast,
leukemia,
lymphoma,
NSCLC,
prostate,
skin cancer
|
No
|
Peginterferon alfa-2a |
Biologic therapy (BRM, immunotherapy)
|
Kidney,
leukemia,
skin cancer
|
Yes
|
MAGE-12:170-178 |
Biologic therapy (BRM, immunotherapy)
|
Breast,
skin cancer
|
Yes
|
Triapine |
Chemotherapy
|
biliary,
Breast,
colorectal,
gallbladder,
head & neck,
leukemia,
lung,
prostate,
skin cancer
|
Yes
|
TriGem |
Biologic therapy (BRM, immunotherapy)
|
Lung,
skin cancer
|
Yes
|
Trans-Retinoic Acid |
Differentiation inducing agent
|
Leukemia,
skin cancer
|
No
|
Diaziquone |
Chemotherapy
|
Bladder,
brain,
skin cancer
|
Yes
|
COL-3 |
Chemotherapy
|
Brain,
other cancer,
skin
|
Yes
|
EMD121974 |
Chemotherapy
|
Brain,
other cancer,
skin
|
Yes
|
Peginterferon alfa-2b |
Biologic therapy (BRM, immunotherapy)
|
Leukemia,
other cancer,
skin
|
Yes
|
Endostatin |
Biologic therapy (BRM, immunotherapy)
|
Colorectal,
other cancer,
skin
|
Yes
|
Incel |
Ancillary Agent
|
Breast,
lung,
other cancer,
ovarian,
prostate,
sarcoma
|
Yes
|
Perifosine |
Chemotherapy
|
Head & neck,
melanoma,
metastatic cancers,
pancreatic,
prostate cancer,
sarcoma
|
Yes
|
Skeletal Targeted Radiotherapy |
Radiation
|
Multiple myeloma,
sarcoma
|
Yes
|
Irofulven |
Chemotherapy
|
Brain,
breast,
cervical,
gastric,
leukemia,
liver,
lung,
melanoma,
multiple myeloma,
ovarian,
ovary,
pancreatic,
primary peritoneal carcinoma,
prostate cancer,
sarcoma
|
Yes
|
MGV Vaccine |
Biologic therapy (BRM, immunotherapy)
|
Colorectal,
gastric,
lung cancer,
lymphoma,
neuroblastoma,
sarcoma
|
Yes
|
TNFerade |
Biologic therapy (BRM, immunotherapy)
|
Esophageal,
gastric,
pancreatic cancer,
sarcoma
|
Yes
|
ONYX-015 |
Chemotherapy
|
Brain,
colorectal,
head & neck,
liver,
lung,
ovarian,
pancreatic cancer,
sarcoma
|
Yes
|
Semaxanib |
Chemotherapy
|
Breast,
colorectal,
lung cancer,
other cancer,
sarcoma
|
Yes
|
Genasense |
Chemotherapy
|
Breast,
colorectal,
kidney,
leukemia,
lung,
lymphoma,
melanoma,
multiple myeloma,
pancreatic cancer,
prostate,
sarcoma
|
Yes
|
Temsirolimus |
Chemotherapy
|
Kidney,
Mantle cell lymphoma,
breast,
colorectal,
lung,
ovarian,
pancreatic,
prostate cancer,
sarcoma
|
Yes
|
Cotara (TNT - Tumor Necrosis Therapy) |
Radiation
|
Brain,
colorectal,
liver,
pancreatic cancer,
sarcoma
|
Yes
|
Cediranib |
Chemotherapy
|
glioblastoma,
NSCLC,
renal cell
|
Yes
|
Medroxyprogesterone Acetate |
Hormones and hormonal mechanisms
|
Endometrial cancer,
renal cancer
|
Yes
|
Decapeptyl |
Hormones and hormonal mechanisms
|
Ovarian,
prostate cancers
|
Yes
|
Dienestrol |
Hormones and hormonal mechanisms
|
Breast,
prostate cancers
|
Yes
|
Triptorelin |
Hormones and hormonal mechanisms
|
Ovarian,
prostate cancers
|
Yes
|
HER-2/neu Vaccine |
Biologic therapy (BRM, immunotherapy)
|
Breast,
ovarian,
prostate cancer
|
Yes
|
Squalamine |
Chemotherapy
|
Brain,
lung,
ovarian,
prostate cancer
|
Yes
|
Neovastat |
Chemotherapy
|
Breast,
kidney,
lung,
multiple myeloma,
prostate cancer
|
Yes
|
SGN-15 |
Chemotherapy
|
Breast,
colorectal,
lung,
ovarian,
prostate cancer
|
Yes
|
Satraplatin |
Chemotherapy
|
Lung,
ovarian,
prostate cancer
|
Yes
|
SR48692 |
Chemotherapy
|
Pancreatic,
prostate cancer
|
Yes
|
Lutrin |
Radiation
|
Breast,
prostate cancer,
GI sites,
GEP-NETs
|
Yes
|
SGN-10 |
Chemotherapy
|
Breast,
colorectal,
lung,
ovarian,
pancreatic,
prostate cancer
|
Yes
|
MVA-Muc1-IL2 |
Biologic therapy (BRM, immunotherapy)
|
Breast,
lung,
prostate cancer
|
Yes
|
GPI-0100 Immune Enhancer (Adjuvant) |
Biologic therapy (BRM, immunotherapy)
|
Breast,
prostate cancer
|
Yes
|
GCS-100 |
Chemotherapy
|
Colorectal,
pancreatic,
prostate cancer
|
Yes
|
Trastuzumab |
Biologic therapy (BRM, immunotherapy)
|
Breast,
colorectal,
lung,
ovarian,
pancreatic,
prostate cancer
|
Yes
|
Doxorubicin |
Chemotherapy
|
Bladder,
breast,
liver,
multiple myeloma,
ovarian,
pancreatic,
prostate cancer
|
Yes
|
Trimetrexate Glucuronate |
Chemotherapy,
AIDS drug
|
Breast,
colorectal,
gastric,
lung,
prostate cancer
|
Yes
|
Stilboestrol Dipropionate |
Hormones and hormonal mechanisms
|
Breast,
prostate cancer
|
Yes
|
Xcellerate |
Biologic therapy (BRM, immunotherapy)
|
Kidney,
prostate cancer
|
Yes
|
Zoladex |
Hormones and hormonal mechanisms
|
Breast,
prostate cancer
|
Yes
|
RAS 5-17 Peptide Vaccine |
Biologic therapy (BRM, immunotherapy)
|
Colorectal,
lung,
other,
pancreatic,
prostate cancer
|
Yes
|
Trisenox |
Chemotherapy
|
Cervical,
kidney,
leukemia,
multiple myeloma,
neuroblastoma,
prostate cancer
|
Yes
|
Panitumumab |
Biologic therapy (BRM, immunotherapy)
|
Colorectal,
kidney,
lung,
prostate cancer
|
Yes
|
GVAX Lung Cancer Vaccine |
Biologic therapy (BRM, immunotherapy)
|
Breast,
leukemia,
lung,
multiple myeloma,
pancreatic,
prostate cancer
|
Yes
|
GnRH Pharmaccine |
Hormones and hormonal mechanisms
|
Breast,
prostate cancer
|
Yes
|
Gallium Maltolate |
Chemotherapy
|
Hepatocellular carcinoma (HCC),
Lymphoma,
multiple myeloma,
prostate cancer
|
Yes
|