Lenalidomide |
Biologic therapy (BRM, immunotherapy)
|
5q- MDS,
CLL,
MDS,
Multiple myeloma,
melanoma,
Lymphoma
|
Yes
|
Intravenous Immune Globulin |
Biologic therapy (BRM, immunotherapy)
|
AIDS,
CLL,
Opportunistic infection
|
Yes
|
Sulfadiazine |
Ancillary Agent,
AIDS drug
|
AIDS,
Opportunistic infection
|
No
|
Interferon Alfa-2a |
Biologic therapy (BRM, immunotherapy)
|
AIDS,
Opportunistic infection
|
Yes
|
Interleukin-6 |
Biologic therapy (BRM, immunotherapy)
|
AIDS,
Opportunistic infection
|
Yes
|
Sulfamethoxazole |
Ancillary Agent,
AIDS drug
|
AIDS,
Opportunistic infection
|
No
|
Recombinant Soluble Human CD4 |
Biologic therapy (BRM, immunotherapy)
|
AIDS,
Opportunistic infection
|
Yes
|
Poly I: Poly C |
AIDS drug
|
AIDS,
Opportunistic infection
|
No
|
Somatrem |
Hormones and hormonal mechanisms
|
AIDS,
Opportunistic infection
|
Yes
|
Acetylcysteine |
Ancillary Agent
|
AIDS,
Opportunistic infection
|
No
|
Interleukin-1 beta |
Biologic therapy (BRM, immunotherapy)
|
AIDS,
Opportunistic infection
|
Yes
|
Malathion |
AIDS drug
|
AIDS,
Opportunistic infection
|
No
|
Interferon Alfa-n1 |
Biologic therapy (BRM, immunotherapy)
|
AIDS,
Opportunistic infection
|
Yes
|
Erythropoietin |
Ancillary Agent
|
AIDS,
Opportunistic infection
|
No
|
Interferon natural |
Biologic therapy (BRM, immunotherapy)
|
AIDS,
Opportunistic infection
|
Yes
|
Lomotil |
Ancillary Agent,
AIDS drug
|
AIDS,
Opportunistic infection
|
No
|
Metronidazole |
Ancillary Agent,
AIDS drug,
Other therapy
|
AIDS,
Opportunistic infection
|
See Remarks
|
Voriconazole |
AIDS drug
|
AIDS,
Opportunistic infection
|
No
|
Sparfloxacin |
Ancillary Agent,
AIDS drug
|
AIDS,
Opportunistic infection
|
No
|
Spiramycin |
Ancillary Agent,
AIDS drug
|
AIDS,
Opportunistic infection
|
No
|
Inolimomab |
AIDS drug
|
AIDS,
Opportunistic infection
|
Yes
|
Interferon gamma-1b |
Biologic therapy (BRM, immunotherapy)
|
AIDS,
Opportunistic infection
|
Yes
|
Mexiletine Hydrochloride |
AIDS drug
|
AIDS,
Opportunistic infection
|
No
|
Trimethoprim |
Ancillary Agent,
AIDS drug
|
AIDS,
Opportunistic infection
|
No
|
Interleukin-10 |
Biologic therapy (BRM, immunotherapy)
|
AIDS,
Opportunistic infection
|
Yes
|
Interferon beta-1b |
Ancillary Agent
|
AIDS,
Opportunistic infection
|
No
|
Miconazole |
AIDS drug
|
AIDS,
Opportunistic infection
|
No
|
Mitoguazone |
Chemotherapy
|
AIDS,
Opportunistic infection
|
Yes
|
Nitrofurazone |
Ancillary Agent
|
AIDS,
Opportunistic infection
|
No
|
Lentinan |
Biologic therapy (BRM, immunotherapy),
AIDS drug
|
AIDS,
Opportunistic infection
|
Yes
|
Mupirocin |
Ancillary Agent
|
AIDS,
Opportunistic infection
|
No
|
Letrazuril |
AIDS drug
|
AIDS,
Opportunistic infection
|
No
|
Interferon alfacon-1 |
Biologic therapy (BRM, immunotherapy)
|
AIDS,
Opportunistic infection
|
Yes
|
Milodistim |
Ancillary Agent
|
AIDS,
Opportunistic infection
|
No
|
Tioconazole |
AIDS drug
|
AIDS,
Opportunistic infection
|
No
|
CSF-2 |
Ancillary Agent
|
AIDS,
Opportunistic infection
|
No
|
Interleukin-2 |
Biologic therapy (BRM, immunotherapy)
|
AIDS,
breast,
head & neck cancer,
leukemia,
lymphoma,
Opportunistic infection
|
Yes
|
SGN-30 |
Chemotherapy
|
ALCL,
Lymphoma
|
Yes
|
SCH-900776 |
Chemotherapy
|
ALL,
AML,
CML,
Hodgkin,
NHL
|
Yes
|
Clofarabine |
Chemotherapy
|
ALL,
AML,
CML,
Leukemia,
lymphoma,
myeloproliferative disease,
other cancer
|
Yes
|
Cytarabine |
Chemotherapy
|
ALL,
AML,
CML,
head and neck,
Hodgkin's disease,
leukemia,
Meningeal leukemia,
NHL
|
Yes
|
Treosulfan |
Chemotherapy
|
ALL,
AML,
MDS
|
No
|
Onco-TCS |
Chemotherapy
|
ALL,
leukemia,
Lung cancer,
lymphoma
|
Yes
|
SKI-606 |
Chemotherapy
|
AML
|
Yes
|
Cyclopentenyl-cytosine |
Chemotherapy
|
AML
|
Yes
|
XIAP antisense |
Chemotherapy
|
AML
|
Yes
|
Valproic acid |
Chemotherapy
|
AML,
CLL,
lymphocytic lymphoma
|
See Remarks
|
SB-1518 |
Chemotherapy
|
AML,
CML,
MDS
|
Yes
|
Lovastatin |
Chemotherapy
|
AML,
Hepatoma,
stomach
|
Yes
|
LBH-589 |
Chemotherapy
|
AML,
Hodgkin lymphoma,
MDS,
multiple myeloma
|
Yes
|
Cloretazine |
Chemotherapy
|
AML,
Leukemia,
other cancers,
SCLC
|
Yes
|
MGCD0103 |
Chemotherapy
|
AML,
MDS
|
Yes
|
Lintuzumab |
Chemotherapy
|
AML,
MDS
|
Yes
|
LY-2181308 |
Chemotherapy
|
AML,
Prostate
|
Yes
|
Lestaurinib |
Chemotherapy
|
AML,
leukemia,
other cancer,
Pancreatic,
prostate
|
Yes
|
Volasertib |
Chemotherapy
|
AML trials,
Ovarian trials,
Solid tumors trials
|
Yes
|
Tretinoin |
Differentiation inducing agent
|
Acute Promyelocytic leukemia (APL),
AIDS,
head & neck cancer,
Opportunistic infection
|
See Remarks
|
Asparaginase |
Chemotherapy
|
Acute lymphoblastic leukemia (ALL)
|
Yes
|
Erwinaze |
Chemotherapy
|
Acute lymphoblastic leukemia (ALL)
|
Yes
|
Omacetaxine |
Chemotherapy
|
Acute lymphoblastic leukemia (ALL),
Acute myelogenous leukemia (AML),
Chronic myelogenous leukemia (CML),
Myelodysplastic syndrome (MDS)
|
Yes
|
Idarubicin |
Chemotherapy
|
Acute lymphoblastic leukemia (ALL),
Acute myelogenous leukemia (AML),
Chronic myelogenous leukemia in blast crises,
Myelodysplastic syndromes (MDS)
|
Yes
|
Methotrexate |
Chemotherapy
|
Acute lymphoblastic leukemia (ALL),
Bladder cancer,
Breast,
Gestational trophoblastic cancer,
head & neck cancer,
lymphoma,
Meningeal leukemia,
Non-Hodgkin lymphoma,
Osteogenic sarcoma,
Primary CNS lymphoma
|
Yes
|
Roscovitine |
Chemotherapy
|
Acute myelogenous leukemia (AML),
B-cell lymphomas,
Non small cell lung cancer (NSCLC)
|
Yes
|
Mitoxantrone |
Chemotherapy
|
Acute myelogenous leukemia (AML),
Breast,
Non-Hodgkin lymphoma,
Prostate- advanced hormone-refractory
|
Yes
|
Vanflyta |
Chemotherapy
|
Acute myeloid leukemia,
AML
|
Yes
|
KW-0761 |
Chemotherapy
|
Adult T-cell leukemia/lymphoma,
peripheral T-cell leukemia/lymphoma
|
Yes
|
XL-147 |
Chemotherapy
|
Advanced Endometrium,
lymphoma,
Mets breast,
NSCLC,
ovarian
|
Yes
|
Tetrahydrouridine |
Chemotherapy
|
Advanced solid tumors
|
Yes
|
Carboplatin |
Chemotherapy
|
All cancers
|
Yes
|
Brentuximab vedotin |
Biologic therapy (BRM, immunotherapy)
|
Anaplastic large cell lymphoma (ALCL),
Hodgkin Lymphoma
|
Yes
|
Norethandrolone |
Hormones and hormonal mechanisms
|
Aplastic anemia
|
Yes
|
Ketoconazole |
Hormones and hormonal mechanisms
|
As a testosterone blocker for advanced prostate cancer,
as an antifungal for AIDS,
opportunistic infections
|
Yes
|
Flavopiridol |
Chemotherapy
|
B-cell CLL,
Colorectal,
lung,
other cancer,
prolymphocytic leukemia arising from CLL,
small lymphocytic lymphoma
|
Yes
|
MEDI-551 |
Biologic therapy (BRM, immunotherapy)
|
B-cell malignancies
|
Yes
|
Ibrutinib |
Chemotherapy
|
B-cell malignancies,
CLL,
Mantle cell lymphoma,
Multiple myeloma,
NHL,
Waldentrom macroglobulinemia (WM),
diffuese B-cell lymphoma,
SLL
|
Yes
|
Vismodegib |
Chemotherapy
|
Basal cell carcinoma, skin
|
Yes
|
Propranolol |
Other therapy
|
Benign hemangioma
|
No
|
Ziihera |
Biologic therapy (BRM, immunotherapy)
|
Bile ducts, Gall bladder
|
Yes
|
Ethylchlorformate |
Biologic therapy (BRM, immunotherapy)
|
Bladder
|
Yes
|
Padcev |
Biologic therapy (BRM, immunotherapy)
|
Bladder
|
Yes
|
Erdafitinib |
Chemotherapy
|
Bladder
|
Yes
|
Enfortumab vedotin |
Biologic therapy (BRM, immunotherapy)
|
Bladder
|
Yes
|
Anktiva |
Biologic therapy (BRM, immunotherapy)
|
Bladder
|
Yes
|
Jelmyto |
Chemotherapy
|
Bladder
|
Yes
|
Bropirimine |
Biologic therapy (BRM, immunotherapy)
|
Bladder
|
Yes
|
Gemcitabine |
Chemotherapy
|
Bladder,
Breast,
non-small cell lung,
ovarian,
pancreatic cancer,
Soft Tissue Sarcoma
|
Yes
|
Ifosfamide |
Chemotherapy
|
Bladder,
Cervical cancer,
Ewing sarcoma,
Head and Neck,
Hodgkin lymphoma,
Non-Hodgkin lymphoma,
Non-small cell and small cell lung cancer,
Soft tissue sarcoma, osteogenic sarcoma,
Testicular cancer
|
Yes
|
Durvalumab |
Biologic therapy (BRM, immunotherapy)
|
Bladder,
Lung,
Biliary tract,
Endometrium,
Liver
|
Yes
|
Atezolizumab |
Biologic therapy (BRM, immunotherapy)
|
Bladder,
Lung,
Liver,
Breast,
Soft tissue
|
Yes
|
Diaziquone |
Chemotherapy
|
Bladder,
brain,
skin cancer
|
Yes
|
Eflornithine |
Chemotherapy
|
Bladder,
brain (glioblastoma),
childhood leukemia,
CML,
skin cancer
|
Yes
|
TOCOSOL |
Chemotherapy
|
Bladder,
breast,
colorectal,
lung,
ovarian cancers
|
Yes
|
Cancer Vaccine |
Biologic therapy (BRM, immunotherapy)
|
Bladder,
breast,
kidney,
ovarian,
skin cancer
|
Yes
|
Doxorubicin |
Chemotherapy
|
Bladder,
breast,
liver,
multiple myeloma,
ovarian,
pancreatic,
prostate cancer
|
Yes
|
Vinflunine |
Chemotherapy
|
Bladder,
breast,
lung,
other
|
Yes
|
Celebrex |
Ancillary Agent
|
Bladder,
breast cancer
|
No
|
Cisplatin |
Chemotherapy
|
Bladder,
ovarian,
testicular cancer
|
Yes
|
Apaziquone |
Ancillary Agent,
Chemotherapy
|
Bladder cancer
|
See Remarks
|
Valrubicin |
Chemotherapy
|
Bladder cancer
|
Yes
|
Levulan |
Ancillary Agent
|
Bladder cancer
|
No
|