STEAM

• Mitomycin
• Thioguanine
• Dactinomycin
• Streptonigrin
• Cyclophosphamide

Name

Mitomycin

Alternate Names

Ametycine

Mito-Medac

Mitocin

Mitocin-C

MitoExtra

Mitomycin-C

Mitomycin-X

Mutamycin

Mutamycine

Abbreviations

MITC

Mito

MITO-C

MMC

MTC

Category

Chemotherapy

Subcategory

Alkylating agent

Antibiotic

NSC Number

26980

026980

Primary Site

Breast

Cervical cancer

Gastric cancer

Head and Neck (in combination with radiation therapy)

Non-small cell lung cancer (NSCLC)

Pancreatic cancer

Superficial bladder cancer

Histology

None

Remarks

FDA approved for treatmen of many cancers.

Coding

This drug should be coded

Name

Thioguanine

Alternate Names

6-Mercaptoguanine

6-Thioguanine

Lanvis

Tabloid

Tioguanin

WR-1141

Abbreviations

6-TG

TG

TT-6

TT-G

Category

Chemotherapy

Subcategory

Antimetabolite

NSC Number

752

000752

Primary Site

None

Histology

None

Remarks

A purine analogue antineoplastic agent; antimetabolite. FDA approved use for acute non-lymphocytic leukemia.

Coding

This drug should be coded

Name

Dactinomycin

Alternate Names

Actinomycin

Actinomycin AIV

Actinomycin C1

Actinomycin D

Actinomycin I1

Actinomycin IV

Actinomycindioic D-acid dilactone

Cosmegen

Dactino-mycin D

Meractinomycin

Oncostatin K

Abbreviations

ACD

ACT

ACT-D

ACTD

Acto-D

AD

Dact

Category

Chemotherapy

Subcategory

Antitumor antibiotic

NSC Number

003053

3053

Primary Site

Ewing's sarcoma

rhabdomyosarcoma

testicular cancer

Wilm's tumor

Histology

None

Remarks

FDA approved use on Ewing's sarcoma, rhabdomyosarcoma, gestational trophoblastic neoplasms, testicular carcinoma, Wilm's tumor (antitumor antibiotic)

Coding

This drug should be coded

Name

Streptonigrin

Alternate Names

5278 R.P.

Bruneomycin

Methyl streptonigrin

Nigrin

Rufochromomycin

Rufocromo-mycin

Abbreviations

SN

STN

STP

Category

Chemotherapy

Subcategory

Antitumor antibiotic

NSC Number

45383

Primary Site

None

Histology

None

Remarks

None

Coding

This drug should be coded

Name

Cyclophosphamide

Alternate Names

Asta B 518

B-518

Clafen Claphene

Cyclophosphamid

Cyclophosphan

Cyclophosphane

Cytophosphan

Cytoxan

Endoxan

Endoxana

Enduxan

Genoxal

Neosar

Procytox

Sendoxan

Tymtram

WR-138719

Abbreviations

CP

CPM

CTX

CTY

CYC

Cyclo

CYT

CYTOX

CYTX

Category

Chemotherapy

Subcategory

Alkylating agent

NSC Number

026271

26271

Primary Site

Breast

leukemia

lymphoma

multiple myeloma

neuroblastoma

ovarian cancer

retinoblastoma

soft tissue sarcoma

Wilm's tumor

Histology

None

Remarks

An effective antineoplastic agent and is used for a variety of cancers. FDA approved uses on breast cancer, ovarian carcinoma, leukemia, lymphomas, multiple myeloma, neuroblastma, retinoblastoma, soft tissue sarcoma, Wilm's tumor. Alkylating agent

Coding

This drug should be coded