Name

SIMAL-second induction/maintenance

Alternate names

None

Primary Site

None

Histology

None

Radiation

None

Remarks

None

Drugs for SIMAL-second induction/maintenance

Name

Alternate Names

Dom-Etoposide
Epipodophyllotoxin derivative
Epipodophyllotoxin ethylidene gluco-pyranoside
Eposine
Ethylidene-Lignan P
Etopophos
Podophyllotoxin derivative
Vepesid
VP 16-213
VP-16
VP-16213
Toposar

Abbreviations

EPEG
VP-16
VP-16-213

Category

Chemotherapy

Subcategory

Epipodophyllotoxin, topoisomerase II inhibitor
Plant alkaloid

NSC Number

141540

Primary Site

Gastric cancer
Hodgkins lymphoma
Lung cancer (NSCLC, SCLC)
Non-Hodgkin lymphoma
testicular cancer (Germ cell tumors)

Histology

None

Remarks

Plant alkaloid. FDA approved use on small-cell lung cancer, testicular cancer.

Coding

This drug should be coded

Name

Alternate Names

Epipodophyllotoxin
Thenylidene
Thenylidene-lignan-P
Vee M-26
Vehem
VM-26
Vumon

Abbreviations

EPT
PTG

Category

Chemotherapy

Subcategory

Topoisomerase inhibitor

NSC Number

122819

Primary Site

None

Histology

None

Remarks

Derivative of podophyllotoxin with antineoplastic activity; plant alkaloid. FDA approved use in pediatric refractory ALL.

Coding

This drug should be coded

Name

Alternate Names

Acetyladriamycin
Cerubidine
Dauno-blastin
Daunomycin
Daunomycin-HCl
Daunorubicin
Daunorubicine
FI-6339
Leuk-aemomycin C
NDC-0082-4155
RP-13057
Rubidomycin
Rubidomycin HCl
Rubomycin C

Abbreviations

Daun
Dauno
DNM
DNR
DRB

Category

Chemotherapy

Subcategory

Antitumor antibiotic

NSC Number

082151
82151

Primary Site

Leukemia

Histology

None

Remarks

FDA approved use on ALL and ANLL; antitumor antibiotic

Coding

This drug should be coded

Name

Alternate Names

Asnase
Asparaginase (Escherichia coli)
Colaspase
Crasnitin#
EC3.1.5.1.
Elspar
Kidrolase
L-Asparaginase
Leunase (enzyme)
MK-965
Re-82-TAD-15

Abbreviations

ASP
ASPA
L-ASE
L-ASP

Category

Chemotherapy

Subcategory

Antineoplastic agent

NSC Number

109229

Primary Site

Acute lymphoblastic leukemia (ALL)

Histology

None

Remarks

Coding

This drug should be coded

Name

Alternate Names

Calcium folinate
Calcium leucovorin
Calcium leucovorin rescue
Citrovorum Factor
Citrovorum factor rescue
Folic acid
Folinic Acid
Lederfoline
Leucosar
Leucovorin Calcium
Leucovorin rescue
Wellcovorin

Abbreviations

C.F.
CF
CL

Category

Ancillary Agent

Subcategory

None

NSC Number

3590
003590

Primary Site

None

Histology

None

Remarks

The pharmacologically active form of folic acid. FDA approved uses as 1st line colorectal carcinoma in combination with 5-FU and to diminish methotrexate toxicity.

Coding

This drug should NOT be coded

Name

Alternate Names

Amethopterin
Antifolan
CL-14377
Folex
Methotrexate Sodium
Mexate
Mexate AQ
Rheumatrex
WR-19039

Abbreviations

MTX

Category

Chemotherapy

Subcategory

Antimetabolite

NSC Number

740
000740

Primary Site

Acute lymphoblastic leukemia (ALL)
Bladder cancer
Breast
Gestational trophoblastic cancer
head & neck cancer
lymphoma
Meningeal leukemia
Non-Hodgkin lymphoma
Osteogenic sarcoma
Primary CNS lymphoma

Histology

None

Remarks

FDA approved uses on ALL, breast cancer, choriocarcinoma, head and neck cancer, lymphoma, and osteosarcoma.

Coding

This drug should be coded

Name

Alternate Names

AC-1075
Alexan
Ara-cytidine
Arabinocytidine
Arabinosylcytosine
Beta-Arabinosylcytosine
Cytarabin
Cytarabine
Cytarabinoside
Cytosar
Cytosar-U
Cytosine Arabinoside
Cytosine arabinoside hydrochloride
Spongocytidine HCL
Tarabine
Tarabine PFS
U-19920
U-19920A
WR-28453

Abbreviations

ara-C
CA
HDA
HDARA-C

Category

Chemotherapy

Subcategory

Antimetabolite

NSC Number

063878
63878

Primary Site

ALL
AML
CML
head and neck
Hodgkin's disease
leukemia
Meningeal leukemia
NHL

Histology

None

Remarks

Antineoplastic agent; antimetabolite. FDA approved uses on Hodgkin's disease, leukemia; under investigation for Rx of Progressive Multifocal Leukoencephalopathy (PML)

Coding

This drug should be coded

Name

Alternate Names

Alti-Prednisone
Alto-Pred
Ancortone
Apo-Prednisone
Colisone
Cortan
Dacortin
Delta-Dome#
Deltasone
Deltra
Fernisone Buffered
Keysone
Liquid Pred
Meticorten
Novo-Prednisone
Orasone
Panasol
Paracort#
Prednicen M
SK-Prednisone
Sterapred DS
Ultracorten
Winpred

Abbreviations

PDN
PRD
PRED

Category

Hormones and hormonal mechanisms

Subcategory

Glucocorticoid

NSC Number

10023
010023

Primary Site

Prednisone is used in regimens to treat multiple sites and histologies

Histology

None

Remarks

Code Prednisone when it is part of a drug regimen.

Do not code Prednisone when it is given to treat symptoms or as a single agent. In most cases when Prednisone is given by itself and not as part of a drug regimen, it does not affect the cancer and would not be coded as treatment.

Coding

Please see remarks for additional information
Glossary