Name

RICE

Alternate names

None

Primary Site

None

Histology

None

Radiation

None

Remarks

None

Drugs for RICE

Name

Alternate Names

Dom-Etoposide
Epipodophyllotoxin derivative
Epipodophyllotoxin ethylidene gluco-pyranoside
Eposine
Ethylidene-Lignan P
Etopophos
Podophyllotoxin derivative
Vepesid
VP 16-213
VP-16
VP-16213
Toposar

Abbreviations

EPEG
VP-16
VP-16-213

Category

Chemotherapy

Subcategory

Epipodophyllotoxin, topoisomerase II inhibitor
Plant alkaloid

NSC Number

141540

Primary Site

Gastric cancer
Hodgkins lymphoma
Lung cancer (NSCLC, SCLC)
Non-Hodgkin lymphoma
testicular cancer (Germ cell tumors)

Histology

None

Remarks

Plant alkaloid. FDA approved use on small-cell lung cancer, testicular cancer.

Coding

This drug should be coded

Name

Alternate Names

Anti-CD20 monoclonal antibodies
C2B8 monoclonal antibody
IDEC-C2B8
MabThera
Monoclonal antibody IDEC-C2B8
Rituxan

Abbreviations

None

Category

Biologic therapy (BRM, immunotherapy)

Subcategory

Cytostatic monoclonal antibody

NSC Number

687451

Primary Site

Leukemia
NHL

Histology

None

Remarks

December 2, 2021 The FDA approved rituximab (Rituxan, Genentech, Inc.) in combination with chemotherapy for pediatric patients (≥6 months to <18 years) with previously untreated, advanced stage, CD20-positive diffuse large B-cell lymphoma (DLBCL), Burkitt lymphoma (BL), Burkitt-like lymphoma (BLL), or mature B-cell acute leukemia (B-AL).

JANUARY 2013 IMPORTANT UPDATE: This drug has changed categories. A comprehensive review has been completed and in keeping with the FDA, Rituximab is to be coded as a Biologic therapy/Immunotherapy agent. Effective with diagnosis date January 1, 2013 forward, code Rituximab as BRM/Immunotherapy. For cases diagnosed prior to January 1, 2013 continue coding as chemotherapy.

FDA approved 2/2006 for treatment of diffuse large B-cell, CD-20 positive non-Hodgkin lymphoma.

FDA approved 9/2006 for non-Hodgkin's B-cell lymphoma. Also used to treat autoimmune disorders, hemolytic anemia and ITP.

FDA approved 2/2010 for use in combination with cyclophosphamide and fludarabine in treatment of CLL.

FDA approved for maintenance therapy for previously untreated follicular CD-20 positive B-cell non-Hodgkin lymphoma who achieved response to rituximab in combination with chemotherapy.

June 22, 2017 FDA granted regular approval to the combination of rituximab and hyaluronidase human (RITUXAN HYCELA) for adult patients with follicular lymphoma, diffuse large B-cell lymphoma, and chronic lymphocytic leukemia.


.

Coding

This drug should be coded

Name

Alternate Names

A-4942
Asta Z-4942
Cyfos#
Holoxan 1000
Ifex
Ifosfamid
Ifoxan
Iphosphamid
Iphosphamide
Iso-endoxan
Isofosfamide
Isophos-phamide
Isophosphamide
Mitoxana
MJF 9325
MJF-9325
Naxamide#
Z4942

Abbreviations

IFX
IPP

Category

Chemotherapy

Subcategory

Alkylating agent

NSC Number

109724

Primary Site

Bladder
Cervical cancer
Ewing sarcoma
Head and Neck
Hodgkin lymphoma
Non-Hodgkin lymphoma
Non-small cell and small cell lung cancer
Soft tissue sarcoma, osteogenic sarcoma
Testicular cancer

Histology

None

Remarks

Antineoplastic with alkylating activity. FDA approved.

Coding

This drug should be coded

Name

Alternate Names

JM 8
JM-8
JM8
Paraplatin

Abbreviations

CBDCA

Category

Chemotherapy

Subcategory

Alkylating agent
Platinum analog

NSC Number

241240

Primary Site

All cancers

Histology

None

Remarks

A platinum-salt alkylating agent.

Coding

This drug should be coded
Glossary