MINE

• Mitoxantrone
• Etoposide
• Mesna
• Ifosfamide

Name

Mitoxantrone

Alternate Names

CL 232315

Mitoxantrone Hydrochloride

Mitozantrone

Novantrone

Abbreviations

DAD

DHAD

DHAQ

Category

Chemotherapy

Subcategory

Antitumor antibiotic

NSC Number

301739

Primary Site

Acute myelogenous leukemia (AML)

Breast

Non-Hodgkin lymphoma

Prostate- advanced hormone-refractory

Histology

None

Remarks

Antibiotic-class antineoplastic. FDA approved uses in adult acute non-lymphocytic leukemia, and prostate cancer pain reduction in combination with prednisone. Novantrone is a synthetic antineoplastic anthracenedione

Coding

This drug should be coded

Name

Etoposide

Alternate Names

Dom-Etoposide

Epipodophyllotoxin derivative

Epipodophyllotoxin ethylidene gluco-pyranoside

Eposine

Ethylidene-Lignan P

Etopophos

Podophyllotoxin derivative

Vepesid

VP 16-213

VP-16

VP-16213

Toposar

Abbreviations

EPEG

VP-16

VP-16-213

Category

Chemotherapy

Subcategory

Epipodophyllotoxin, topoisomerase II inhibitor

Plant alkaloid

NSC Number

141540

Primary Site

Gastric cancer

Hodgkins lymphoma

Lung cancer (NSCLC, SCLC)

Non-Hodgkin lymphoma

testicular cancer (Germ cell tumors)

Histology

None

Remarks

Plant alkaloid. FDA approved use on small-cell lung cancer, testicular cancer.

Coding

This drug should be coded

Name

Mesna

Alternate Names

D 7093

Mesna rescue

Mesnex

Mesnex uroprotection

Mesnum

Mistabron

Mitexan

Mucofluid

Sodium 2-mercaptoethanolsulfonate

UCB 3983

Uromitexan

Abbreviations

None

Category

Ancillary Agent

Subcategory

None

NSC Number

113891

Primary Site

None

Histology

None

Remarks

A prophylactic detoxifying agent used to inhibit hemorrhagic cystitis caused by ifosfamide. FDA approved for bladder protection when using cyclophosphamide (prevents bladder toxicity).

Coding

This drug should NOT be coded

Name

Ifosfamide

Alternate Names

A-4942

Asta Z-4942

Cyfos#

Holoxan 1000

Ifex

Ifosfamid

Ifoxan

Iphosphamid

Iphosphamide

Iso-endoxan

Isofosfamide

Isophos-phamide

Isophosphamide

Mitoxana

MJF 9325

MJF-9325

Naxamide#

Z4942

Abbreviations

IFX

IPP

Category

Chemotherapy

Subcategory

Alkylating agent

NSC Number

109724

Primary Site

Bladder

Cervical cancer

Ewing sarcoma

Head and Neck

Hodgkin lymphoma

Non-Hodgkin lymphoma

Non-small cell and small cell lung cancer

Soft tissue sarcoma, osteogenic sarcoma

Testicular cancer

Histology

None

Remarks

Antineoplastic with alkylating activity. FDA approved.

Coding

This drug should be coded