VBMF

• Fluorouracil
• Methotrexate
• Bleomycin
• Vincristine

Name

Fluorouracil

Alternate Names

5-Fluorouracil

5-Fluracil

Adrucil

Efudex

Fluoroplex

Fluracil

Fluril

Oracil

Ro 2-9757

WR-69596

Abbreviations

5-FU

5FU

FU

Category

Chemotherapy

Subcategory

Antimetabolite

NSC Number

019893

19893

Primary Site

Breast- adjuvant setting and advanced disease

colorectal- adjuvant setting and advanced disease

GI malignancies: anal, esophageal, gastric and pancreatic

Head and Neck cancer

Hepatoma

Ovarian cancer

Skin-Basal cell carcinoma (topical application)

Histology

None

Remarks

Fluorinated pyrimidine; antimetabolite. FDA approved uses on basal cell carcinoma, breast cancer, colorectal cancer, gastric cancer, and pancreatic cancer.

Note: Efudex cream be prescribed to treat AIN III. Code this as chemotherapy.

Coding

This drug should be coded

Name

Methotrexate

Alternate Names

Amethopterin

Antifolan

CL-14377

Folex

Methotrexate Sodium

Mexate

Mexate AQ

Rheumatrex

WR-19039

Abbreviations

MTX

Category

Chemotherapy

Subcategory

Antimetabolite

NSC Number

740

000740

Primary Site

Acute lymphoblastic leukemia (ALL)

Bladder cancer

Breast

Gestational trophoblastic cancer

head & neck cancer

lymphoma

Meningeal leukemia

Non-Hodgkin lymphoma

Osteogenic sarcoma

Primary CNS lymphoma

Histology

None

Remarks

FDA approved uses on ALL, breast cancer, choriocarcinoma, head and neck cancer, lymphoma, and osteosarcoma.

Coding

This drug should be coded

Name

Bleomycin

Alternate Names

Blenoxane

Bleo

Bleo-Cell

Bleo-S

Bleomycin for Injection

Bleomycin sulfate

Oil Bleo

Abbreviations

BLE

BLEO

BLM

Category

Chemotherapy

Subcategory

Antitumor antibiotic

NSC Number

125066

Primary Site

Squamous cell cancers

Histology

None

Remarks

FDA approved uses on squamous cell cervical cancer, head & neck cancer, Hodgkin's and non-Hodgkin's lymphoma, nasopharyngeal cancer, carcinoma, and testicular cancer.

Coding

This drug should be coded

Name

Vincristine

Alternate Names

Compound 37231

Leurocristine Sulfate

Oncovin

Vincasar

Vincasar PFS

Vincristine Sulfate

Vincrystine

Vinkristin

Abbreviations

LCR

VCR

VNCR

Category

Chemotherapy

Subcategory

Plant alkyloid--antimetabolite

NSC Number

067574

67574

Primary Site

None

Histology

None

Remarks

Antineoplastic; vinca plant alkaloid; antimetabolite. FDA approved uses in ALL, Hodgkin's lymphoma, non-Hodgkin's lymphoma, neuroblastoma, rhabomyosarcoma, and Wilm's tumor.

Coding

This drug should be coded