VDT-PACE

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Plant alkaloid. FDA approved use on small-cell lung cancer, testicular cancer.

This drug should be coded

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FDA approved for multiple myeloma 2006; Phase II brain, kidney, liver, lung, leukemia, HD, NHL, melanoma Phase III prostate Tumor Necrosis Factor inhibitor; angiogenesis inhibitor; immunomodulator. Celgene, NCI.

This drug should be coded

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NOTE* Dexamethasone may be coded as either an ancillary drug or hormone. Review chart to determine if given for supportive care or as hormonal therapy. IMPORTANT INFORMATION: dexamethasone is frequently included in treatment regimens, however, this does not indicate it should be coded as hormone therapy. Be sure to review the regimen tab in "Search Database" for additional coding information.

A long-acting corticosteroid (glucocorticoid). In general, this drug is used more commonly for supportive care, and as an antiemetic than it is as hormone therapy. 25 times as potent as cortisol; used topically as an anti-inflammatory and administered orally in replacement therapy for adrenal insufficiency, as an anti-inflammatory and immunosuppressant in a wide variety of disorders, and as an antiemetic in cancer chemotherapy. Dexamethasone and other corticosteroids may be used to control white cell proliferation in hematopoietic diseases and would be coded as hormone therapy for lymphoid leukemia, lymphoma and multiple myeloma.

Please see remarks for additional information

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Phase II liver, pancreatic, Phase III MM, prostate Doxorubicin hydrochloride encapsulated in liposomes formulated with methoxypolyethylene glycol (MPEG). FDA approved use on bladder cancer, breast cancer, gastric cancer, leukemia, small cell lung cancer, lymphoma, neuroblastoma, ovarian cancer, sarcoma, thyroid cancer, Wilm's tumor. ALZA Corp, NeoPharm, Pharmacia, Schering-Plough, Sequus. Antitumor antibiotic

This drug should be coded

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An alkylating antineoplastic agent. FDA approved uses on bladder, ovarian and testicular cancer; miscellaneous agent.

This drug should be coded

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An effective antineoplastic agent and is used for a variety of cancers. FDA approved uses on breast cancer, ovarian carcinoma, leukemia, lymphomas, multiple myeloma, neuroblastma, retinoblastoma, soft tissue sarcoma, Wilm's tumor. Alkylating agent

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November 14, 2014 update: FDA approved to treat multiple myeloma and Mantle cell lymphoma. In clinical trials for breast, colorectal, and lung cancer.

This drug should be coded