Name

SMILE

Alternate names

None

Primary Site

Extranodal natural killer/T-cell lymphoma, nasal type (ENKL)

Histology

None

Radiation

None

Remarks

None

Drugs for SMILE

Name

Alternate Names

Dom-Etoposide
Epipodophyllotoxin derivative
Epipodophyllotoxin ethylidene gluco-pyranoside
Eposine
Ethylidene-Lignan P
Etopophos
Podophyllotoxin derivative
Vepesid
VP 16-213
VP-16
VP-16213
Toposar

Abbreviations

EPEG
VP-16
VP-16-213

Category

Chemotherapy

Subcategory

Epipodophyllotoxin, topoisomerase II inhibitor
Plant alkaloid

NSC Number

141540

Primary Site

Gastric cancer
Hodgkins lymphoma
Lung cancer (NSCLC, SCLC)
Non-Hodgkin lymphoma
testicular cancer (Germ cell tumors)

Histology

None

Remarks

Plant alkaloid. FDA approved use on small-cell lung cancer, testicular cancer.

Coding

This drug should be coded

Name

Alternate Names

Aeroseb-Dex
AK-Dex
AK-Trol
Baldex
Component of Deronil
Component of Dexacidin
Component of Maxitrol
Dalalone
Decaderm
Decadrol
Decadron Tablets
Decajet
Decameth
Decasone
Decaspray
Deenar
Dex-4
Dexacen
Dexacidin
Dexacort Phosphate
Dexameth
Dexasone
Dexasporin
Dexone
Dexsone
Dezone
Gammacorten
Hexadrol
Hexadrol Elixir
Hexadrol Tablets
Infectrol Sterile
Maxidex
Maxitrol
Miral
Mymethasone
Neo-Dexameth
Neodecadron
Neodexair
Ocu-Trol
Oradexon
PMS-Dexamethasone Sodium Phosphate
SK-Dexamethasone
Sofracort
Sofradex
Solurex
Spersadex
Sterile Dexamethasone Acetate
Tobradex
Turbinare Decaron Phosphate

Abbreviations

DECA
DM
DSM

Category

Ancillary Agent
Hormones and hormonal mechanisms

Subcategory

Glucocorticoid. Probably not cancer directed--verify with attending MD.

NSC Number

345211

Primary Site

None

Histology

None

Remarks

NOTE* Dexamethosine may be coded as either an ancillary drug or hormone. Review chart to determine if given for supportive care or as hormonal therapy.

A long-acting corticosteroid (glucocorticoid). In general, this drug is used more commonly for supportive care, and as an antiemetic than it is as hormone therapy. 25 times as potent as cortisol; used topically as an anti-inflammatory and administered orally in replacement therapy for adrenal insufficiency, as an anti-inflammatory and immunosuppressant in a wide variety of disorders, and as an antiemetic in cancer chemotherapy. Dexamethasone and other corticosteroids may be used to control white cell proliferation in hematopoietic diseases and would be coded as hormone therapy for lymphoid leukemia, lymphoma and multiple myeloma.

Coding

Please see remarks for additional information

Name

Alternate Names

Asnase
Asparaginase (Escherichia coli)
Colaspase
Crasnitin#
EC3.1.5.1.
Elspar
Kidrolase
L-Asparaginase
Leunase (enzyme)
MK-965
Re-82-TAD-15

Abbreviations

ASP
ASPA
L-ASE
L-ASP

Category

Chemotherapy

Subcategory

Antineoplastic agent

NSC Number

109229

Primary Site

Acute lymphoblastic leukemia (ALL)

Histology

None

Remarks

Coding

This drug should be coded

Name

Alternate Names

A-4942
Asta Z-4942
Cyfos#
Holoxan 1000
Ifex
Ifosfamid
Ifoxan
Iphosphamid
Iphosphamide
Iso-endoxan
Isofosfamide
Isophos-phamide
Isophosphamide
Mitoxana
MJF 9325
MJF-9325
Naxamide#
Z4942

Abbreviations

IFX
IPP

Category

Chemotherapy

Subcategory

Alkylating agent

NSC Number

109724

Primary Site

Bladder
Cervical cancer
Ewing sarcoma
Head and Neck
Hodgkin lymphoma
Non-Hodgkin lymphoma
Non-small cell and small cell lung cancer
Soft tissue sarcoma, osteogenic sarcoma
Testicular cancer

Histology

None

Remarks

Antineoplastic with alkylating activity. FDA approved.

Coding

This drug should be coded

Name

Alternate Names

Amethopterin
Antifolan
CL-14377
Folex
Methotrexate Sodium
Mexate
Mexate AQ
Rheumatrex
WR-19039

Abbreviations

MTX

Category

Chemotherapy

Subcategory

Antimetabolite

NSC Number

740
000740

Primary Site

Acute lymphoblastic leukemia (ALL)
Bladder cancer
Breast
Gestational trophoblastic cancer
head & neck cancer
lymphoma
Meningeal leukemia
Non-Hodgkin lymphoma
Osteogenic sarcoma
Primary CNS lymphoma

Histology

None

Remarks

FDA approved uses on ALL, breast cancer, choriocarcinoma, head and neck cancer, lymphoma, and osteosarcoma.

Coding

This drug should be coded
Glossary