Name

CYCLONE

Alternate names

None

Primary Site

None

Histology

None

Radiation

None

Remarks

None

Drugs for CYCLONE

Name

Alternate Names

Kyprolis

Abbreviations

None

Category

Chemotherapy

Subcategory

Proteasome inhibitor

NSC Number

None

Primary Site

Multiple myeloma

Histology

None

Remarks

September 4, 2020: FDA has approved Kyprolis (carfilzomib) and Darzalex (daratumumab) in combination with dexamethasone for adult patients with relapsed or refractory multiple myeloma who have received one to three lines of therapy.

July 20, 2012 the FDA approved Kyprolis under the accelerated approval program for the treatment of multiple myeloma.

Coding

This drug should be coded

Name

Alternate Names

K-17
Kevadon
Synovir
Thalomid

Abbreviations

None

Category

Biologic therapy (BRM, immunotherapy)

Subcategory

Antiangiogenic agent for most indications

NSC Number

66847

Primary Site

Brain
kidney
leukemia
liver
lung
lymphoma
multiple myeloma
prostate
skin cancer

Histology

None

Remarks

FDA approved for multiple myeloma 2006; Phase II brain, kidney, liver, lung, leukemia, HD, NHL, melanoma Phase III prostate Tumor Necrosis Factor inhibitor; angiogenesis inhibitor; immunomodulator. Celgene, NCI.

Coding

This drug should be coded

Name

Alternate Names

Aeroseb-Dex
AK-Dex
AK-Trol
Baldex
Component of Deronil
Component of Dexacidin
Component of Maxitrol
Dalalone
Decaderm
Decadrol
Decadron Tablets
Decajet
Decameth
Decasone
Decaspray
Deenar
Dex-4
Dexacen
Dexacidin
Dexacort Phosphate
Dexameth
Dexasone
Dexasporin
Dexone
Dexsone
Dezone
Gammacorten
Hexadrol
Hexadrol Elixir
Hexadrol Tablets
Infectrol Sterile
Maxidex
Maxitrol
Miral
Mymethasone
Neo-Dexameth
Neodecadron
Neodexair
Ocu-Trol
Oradexon
PMS-Dexamethasone Sodium Phosphate
SK-Dexamethasone
Sofracort
Sofradex
Solurex
Spersadex
Sterile Dexamethasone Acetate
Tobradex
Turbinare Decaron Phosphate

Abbreviations

DECA
DM
DSM

Category

Ancillary Agent
Hormones and hormonal mechanisms

Subcategory

Glucocorticoid. Probably not cancer directed--verify with attending MD.

NSC Number

345211

Primary Site

None

Histology

None

Remarks

NOTE* Dexamethosine may be coded as either an ancillary drug or hormone. Review chart to determine if given for supportive care or as hormonal therapy.

A long-acting corticosteroid (glucocorticoid). In general, this drug is used more commonly for supportive care, and as an antiemetic than it is as hormone therapy. 25 times as potent as cortisol; used topically as an anti-inflammatory and administered orally in replacement therapy for adrenal insufficiency, as an anti-inflammatory and immunosuppressant in a wide variety of disorders, and as an antiemetic in cancer chemotherapy. Dexamethasone and other corticosteroids may be used to control white cell proliferation in hematopoietic diseases and would be coded as hormone therapy for lymphoid leukemia, lymphoma and multiple myeloma.

Coding

Please see remarks for additional information

Name

Alternate Names

Asta B 518
B-518
Clafen Claphene
Cyclophosphamid
Cyclophosphan
Cyclophosphane
Cytophosphan
Cytoxan
Endoxan
Endoxana
Enduxan
Genoxal
Neosar
Procytox
Sendoxan
Tymtram
WR-138719

Abbreviations

CP
CPM
CTX
CTY
CYC
Cyclo
CYT
CYTOX
CYTX

Category

Chemotherapy

Subcategory

Alkylating agent

NSC Number

026271
26271

Primary Site

Breast
leukemia
lymphoma
multiple myeloma
neuroblastoma
ovarian cancer
retinoblastoma
soft tissue sarcoma
Wilm's tumor

Histology

None

Remarks

An effective antineoplastic agent and is used for a variety of cancers. FDA approved uses on breast cancer, ovarian carcinoma, leukemia, lymphomas, multiple myeloma, neuroblastma, retinoblastoma, soft tissue sarcoma, Wilm's tumor. Alkylating agent

Coding

This drug should be coded
Glossary