FLOT

• Fluorouracil
• Oxaliplatin
• Docetaxel
• Leucovorin

Name

Fluorouracil

Alternate Names

5-Fluorouracil

5-Fluracil

Adrucil

Efudex

Fluoroplex

Fluracil

Fluril

Oracil

Ro 2-9757

WR-69596

Abbreviations

5-FU

5FU

FU

Category

Chemotherapy

Subcategory

Antimetabolite

NSC Number

019893

19893

Primary Site

Breast- adjuvant setting and advanced disease

colorectal- adjuvant setting and advanced disease

GI malignancies: anal, esophageal, gastric and pancreatic

Head and Neck cancer

Hepatoma

Ovarian cancer

Skin-Basal cell carcinoma (topical application)

Histology

None

Remarks

Fluorinated pyrimidine; antimetabolite. FDA approved uses on basal cell carcinoma, breast cancer, colorectal cancer, gastric cancer, and pancreatic cancer.

Note: Efudex cream be prescribed to treat AIN III. Code this as chemotherapy.

Coding

This drug should be coded

Name

Oxaliplatin

Alternate Names

1-OHP

1670 RBl Eloxatin

Eloxatin

L-OHP

Oxalatoplatin

Oxalatoplatinum

PR-54780

RP-54780

Transplatin

Abbreviations

None

Category

Chemotherapy

Subcategory

Platinum analog

NSC Number

266046

Primary Site

Colorectal

gastro-esophageal cancers, metastatic

liver

ovarian

pancreatic cancer

Histology

None

Remarks

A platinum-containing antineoplastic that is usually given in combiantion with 5-FU.

Coding

This drug should be coded

Name

Docetaxel

Alternate Names

LIT-976

RP-56976

Taxotere

Abbreviations

None

Category

Chemotherapy

Subcategory

Taxane

NSC Number

628503

Primary Site

Breast

gastric

head & neck

non-small cell lung

ovarian

prostate cancer

Histology

None

Remarks

FDA approved for use on breast, prostate, stomach and NSCLC. Aventis Pharmaceuticals.

Coding

This drug should be coded

Name

Leucovorin

Alternate Names

Calcium folinate

Calcium leucovorin

Calcium leucovorin rescue

Citrovorum Factor

Citrovorum factor rescue

Folic acid

Folinic Acid

Lederfoline

Leucosar

Leucovorin Calcium

Leucovorin rescue

Wellcovorin

Abbreviations

C.F.

CF

CL

Category

Ancillary Agent

Subcategory

None

NSC Number

3590

003590

Primary Site

None

Histology

None

Remarks

The pharmacologically active form of folic acid. FDA approved uses as 1st line colorectal carcinoma in combination with 5-FU and to diminish methotrexate toxicity.

Coding

This drug should NOT be coded