Beginning with cancer cases diagnosed January 1, 2018 and forward, SEER registries in the United States collect Extent of Disease (EOD) information. The three main data items are EOD Primary Tumor, EOD Regional Nodes and EOD Mets. Using these three data items, an EOD TNM T, EOD TNM N and EOD TNM M are derived, along with an EOD TNM Stage Group based on the AJCC 8th edition. SEER developed a staging database referred to as the SEER*RSA that provides information about each cancer (primary site/histology/other factors defined).

The EOD General Instructions provide guidance on how to code EOD.

Refer to SEER*RSA for schema-specific codes and coding instructions.

Refer to the Historical Staging and Coding Manuals for previous versions of the manual.

EOD 2018 Consolidation Manual

Published October 6, 2023

The EOD 2018 Consolidation Manual was developed to assist central registries with consolidation of EOD data items: EOD Extension, EOD Lymph Nodes, and EOD Mets. Each schema was reviewed by the EOD Consolidation workgroup, which was formed specifically for this purpose. Every EOD schema is covered.

At this time, EOD consolidation is not automated.

This manual can be used for cases diagnosed 2018 and forward. The current version of this manual is version 3.1 to align with the current EOD version.

If you have any questions regarding the EOD Consolidation Manual, please submit the question to Ask a SEER Registrar and choose “EOD.”

EOD Consolidation Manual (PDF, 13.3 MB)

Suggested Citations

Ruhl JL, Callaghan C, Schussler N (eds.) Extent of Disease (EOD) 2018 General Coding Instructions, National Cancer Institute, Bethesda, MD, 2024

Adams, S., Ruhl, J., Schussler, N. (Oct 2023). Extent of Disease (EOD) Consolidation Manual. National Cancer Institute, Rockville, MD, 20850.