The adapted classification scheme for tumors of adolescents and young adults (AYA) is based on the classification scheme proposed by RD Barr and colleagues1. The SEER AYA site recode variable was updated from the original ICD-O-2 based classification scheme using ICD-O-3 definitions for cancer morphology and topography.

The SEER AYA site recode was developed to better define the major cancer sites that affect individuals between 15 and 39 years of age. It is intended to facilitate SEER's reporting of cancer incidence rates and trends. The variable was added to the SEER databases as a convenience for researchers.

Variable Definitions

Version Definition
AYA Site Recode 2020 Revision
  • Recommended variable for use in the 1975-2018 SEER Research Data (November 2020 submission)
AYA Site Recode/WHO 2008
  • Based on ICD-O-3, updated for Hematopoietic codes based on WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues (2008).
  • Recommended variable for use in the 1973-2010 through 1975-2017 SEER Research Data (November 2012 - November 2019 submissions)
AYA Site Recode (Original Definition)
  • Based on ICD-O-3
  • Recommended variable use in the 1973-2009 SEER Research Data (November 2011 submission) and earlier versions.

1 Barr RD, Holowaty EJ, Birch JM. Classification Scheme for tumors diagnosed in adolescents and young adults. Cancer 2006;106(7):1425-30.