This initiative involves a multilevel review process, including pathologists and tumor registrars, of standards for tumor site-morphology combinations, terminology, and coding. These standards (valid, unlikely, and impossible) will be the source of information for the 2024 Cancer PathCHART ICD-O-3 Site Morphology Validation List and the NAACCR site/type edits, which will be freely available to cancer registration software vendors and any other end users in easily consumed, computer-readable formats (e.g., XLSX, CSV, XML, JSON).

The aim of this multilevel review process is to assign one of the Cancer PathCHART (CPC) designations: Valid, Unlikely, or Impossible, to all site-morphology combinations.
The first review is by a SEER*ClinCORE subspecialty pathologist. The second level of independent review is performed in parallel by 2 to 3 subject matter expert pathologists. Any discrepancies in designations are resolved in a consensus meeting where pathologists and cancer registrars participate.
The following cancer registrars' review focuses on discovering potential conflicts between the CPC designations and other sources used by cancer registrars. Discrepancies are resolved in a consensus meeting with cancer registrars and the SEER*ClinCORE pathologist.
Contributors toward 2024 Implementation
Cancer PathCHART Leadership

- Brian Rous - Co-Chair
- Alison Van Dyke - Co-Chair
- Serban Negoita - NCI Expert
- Gonçalo Forjaz - Content WG
- Kathleen Loomis - Database Dev WG
- Peggy Adamo - Implementation WG
- NT Tran - Former NCI Fellow
- Annelie Landgren - NCI Project Manager
- Camille Goff - NCI Project Manager
- Lois Dickie - Content/Implementation WGs
- Jennifer Ruhl - Sarcomas/Hematopoietic
- Huann-Sheng Chen - Statistician

- Loria Pollack - (CDC/NPCR)
Ret. USPHS 7/1/2023 - Kay Washington - (CAP & AJCC Committees)
- Rich Moldwin - (CAP)
- Michael Eden - (NHS)
- Joseph Sirintrapun - (MSKCC)
- Liesbet Van Eycken - (ENCR/IACR)
- Jim Hofferkamp - (NAACCR)
Reviewing Subspecialty Pathologists

- Aaron Auerbach - Hematopathology
- James Connolly - Breast Pathology
- Brent Harris - Neuropathology
- Pei Hui - GYN Pathology
- Peter Humphrey - Male Genital/Urinary Pathology
- Jim Lewis Jr. - Head/Neck Pathology & HPV
- Ricardo Lloyd - Endocrine Pathology
- Jessica Davis - Bone/Soft Tissue & Pediatric Pathology
- Kay Washington - GI Pathology
- Priya Nagarajan - Dermatopathology
Bone & Soft Tissue
- John SA Chrisinger, MD
- Karen Fritchie, MD
- Paari Murugan, MD
Breast
- Veerle Bossuyt, MD
- Mary Elizabeth Edgerton, MD, PhD
- Patrick L. Fitzgibbons, MD
Digestive System
- Volkan Adsay, MD
- Olca Basturk, MD
- Norman Carr, MB, BS, FRCPath
- Dhanpat Jain, MD
- David Klimstra, MD
- Sanjay Kakar, MD
- Gregory Lauwers, MD
- Robert Odze, MD
- Asif Rashid, MBBS, PhD
- Romil Saxena, MD
- Chan Juan Shi, MD, PhD
- Aatur Singhi, MD, PhD
- Mike Torbenson, MD
- Tsung-The Wu, MD, PhD
Female Genital System
- Elizabeth Euscher, MD
- Ian Hagemann, MD, PhD
- Martin Kobel, MD
- Uma Krishnamurti, MD, MBBS, PhD
- Mohammad Ruhul Quddus, MD
- Jian-Jun Wei, MD
Male Genital System
- Jonathan Epstein, MD
- Gladell P. Paner, MD
- John Robert Srigley, MD, FRCPath
Urinary System
- Jonathan Epstein, MD
- Lara Rabih Harik, MD
- Peter Humphrey, MD, PhD

- Lois Dickie - Team Lead
- Carolyn Callaghan, WA
- Jodee Chumlee, KY
- Connie Boone, SC
- Carmela Groves - Westat Inc
- Laura Patterson, NY
If you have any questions please contact the Cancer PathCHART team: NCICancerPathCHART@mail.nih.gov.