The table below provides the definition for this International Classification of Childhood Cancer (ICCC) variable. To see other variable definitions, see the ICCC home page.

Site Group ICD-O-3 Site ICD-O-3 Histology (Type) ICD-O-3 Behavior Extended Classification Main Classification
I. Leukemias, myeloproliferative diseases, and myelodysplastic diseases
(a) Lymphoid leukemias
(a.1) Precursor cell leukemias C000-C809 9835-9836 3 001 011
C420-C421, C424 9811-9818, 9837 3 001 011
(a.2) Mature B-cell leukemias C000-C809 9826, 9832-9833, 9940 3 002 011
C420-C421, C424 9823 3 002 011
(a.3) Mature T-cell and NK cell leukemias C000-C809 9831, 9834, 9948 3 003 011
C420-C421, C424 9827 3 003 011
(a.4) Lymphoid leukemia, NOS C000-C809 9820 3 004 011
(b) Acute myeloid leukemias C000-C809 9840, 9861, 9865-9867, 9869-9874, 9891, 9895-9898, 9910-9911, 9920, 9931 3 005 012
(c) Chronic myeloproliferative diseases C000-C809 9863, 9875-9876, 9950, 9960-9964 3 006 013
(d) Myelodysplastic syndrome and other myeloproliferative diseases C000-C809 9945-9946, 9975, 9980, 9982-9987, 9989, 9991-9992 3 007 014
(e) Unspecified and other specified leukemias C000-C809 9800-9801, 9805-9809, 9860, 9930, 9965-9967, 9971 3 008 015
II. Lymphomas and reticuloendothelial neoplasms
(a) Hodgkin lymphomas C000-C809 9650-9655, 9659, 9661-9665, 9667 3 009 021
(b) Non-Hodgkin lymphomas (except Burkitt lymphoma)
(b.1) Precursor cell lymphomas C000-C809 9727-9729 3 010 022
C000-C419, C422-C423, C425-C809 9811-9818, 9837 3 010 022
(b.2) Mature B-cell lymphomas (except Burkitt lymphoma) C000-C809 9597, 9670-9671, 9673, 9675, 9678-9680, 9684, 9688-9691, 9695, 9698-9699, 9712, 9731-9735, 9737-9738, 9761-9762, 9764-9766, 9769, 9970 3 011 022
C000-C419, C422-C423, C425-C809 9823 3 011 022
(b.3) Mature T-cell and NK-cell lymphomas C000-C809 9700-9702, 9705, 9708-9709, 9714, 9716-9719, 9724-9726, 9767-9768 3 012 022
C000-C419, C422-C423, C425-C809 9827 3 012 022
(b.4) Non-Hodgkin lymphomas, NOS C000-C809 9591, 9760 3 013 022
(c) Burkitt lymphoma C000-C809 9687 3 014 023
(d) Miscellaneous lymphoreticular neoplasms C000-C809 9740-9742, 9750-9759 3 015 024
(e) Unspecified lymphomas C000-C809 9590, 9596 3 016 025
III. CNS and miscellaneous intracranial and intraspinal neoplasms
(a) Ependymomas and choroid plexus tumor
(a.1) Ependymomas C000-C809 9383, 9391-9394 0,1,3 017 031
(a.2) Choroid plexus tumor C000-C809 9390 0,1,3 018 031
(b) Astrocytomas C723 9380 0,1,3 019 032
C000-C809 9384, 9400-9411, 9420-9424, 9440-9442 0,1,3 019 032
(c) Intracranial and intraspinal embryonal tumors
(c.1) Medulloblastomas C000-C809 9470-9472, 9474, 9480 0,1,3 020 033
(c.2) PNET C000-C809 9473 0,1,3 021 033
(c.3) Medulloepithelioma C700-C729 9501-9504 0,1,3 022 033
(c.4) Atypical teratoid/rhabdoid tumor C000-C809 9508 0,1,3 023 033
(d) Other gliomas
(d.1) Oligodendrogliomas C000-C809 9450, 9451, 9460 0,1,3 024 034
(d.2) Mixed and unspecified gliomas C700-C722, C724-C729, C751, C753 9380 0,1,3 025 034
C000-C809 9382 0,1,3 025 034
(d.3) Neuroepithelial glial tumors of uncertain origin C000-C809 9381, 9430, 9444 0,1,3 026 034
(e) Other specified intracranial and intraspinal neoplasms
(e.1) Pituitary adenomas and carcinomas C000-C809 8270-8281, 8300 0,1,3 027 035
(e.2) Tumors of the sellar region (craniopharyngiomas) C000-C809 9350-9352, 9582 0,1,3 028 035
(e.3) Pineal parenchymal tumors C000-C809 9360-9362 0,1,3 029 035
(e.4) Neuronal and mixed neuronal-glial tumors C000-C809 9412-9413, 9492-9493, 9505-9507 0,1,3 030 035
(e.5) Meningiomas C000-C809 9530-9539 0,1,3 031 035
(f) Unspecified intracranial and intraspinal neoplasms C700-C729, C751-C753 8000-8005 0,1,3 032 036
IV. Neuroblastoma and other peripheral nervous cell tumors
(a) Neuroblastoma and ganglioneuroblastoma C000-C809 9490, 9500 3 033 041
(b) Other peripheral nervous cell tumors C000-C809 8680-8683, 8690-8693, 8700, 9520-9523 3 034 042
C000-C699, C739-C768, C809 9501-9504 3 034 042
V. Retinoblastoma C000-C809 9510-9514 3 035 050
VI. Renal tumors
(a) Nephroblastoma and other nonepithelial renal tumors
(a.1) Nephroblastoma C000-C809 8959-8960 3 036 061
(a.2) Rhabdoid renal tumor C649 8963 3 037 061
(a.3) Kidney sarcomas C000-C809 8964-8967 3 038 061
(a.4) pPNET of kidney C649 9364 3 039 061
(b) Renal carcinomas C649 8010-8041, 8050-8075, 8082, 8120-8122, 8130-8141, 8143, 8155, 8190-8201, 8210-8211, 8221-8231, 8240-8241, 8244-8246, 8260-8263, 8290, 8310, 8320, 8323, 8401, 8430, 8440, 8480-8490, 8504, 8510, 8550, 8560-8576 3 040 062
C000-C809 8311-8312, 8316-8319, 8361 3 040 062
(c) Unspecified malignant renal tumors C649 8000-8005 3 041 063
VII. Hepatic tumors
(a) Hepatoblastoma C000-C809 8970 3 042 071
(b) Hepatic carcinomas C220, C221 8010-8041, 8050-8075, 8082, 8120-8122, 8140-8141, 8143, 8155, 8190-8201, 8210-8211, 8230, 8231, 8240-8241, 8244-8246, 8260-8264, 8310, 8320, 8323, 8401, 8430, 8440, 8480-8490, 8504, 8510, 8550, 8560-8576 3 043 072
C000-C809 8160-8180 3 043 072
(c) Unspecified malignant hepatic tumors C220-C221 8000-8005 3 044 073
VIII. Malignant bone tumors
(a) Osteosarcomas C400-C419, C760-C768, C809 9180-9187, 9191-9195, 9200 3 045 081
(b) Chondrosarcomas C400-C419, C760-C768, C809 9210, 9220, 9240 3 046 082
C000-C809 9221, 9230, 9241-9243 3 046 082
(c) Ewing tumor and related sarcomas of bone
(c.1) Ewing tumor and Askin tumor of bone C400-C419, C760-C768, C809 9260 3 047 083
C400-C419 9365 3 047 083
(c.2) pPNET of bone C400-C419 9363-9364 3 048 083
(d) Other specified malignant bone tumors
(d.1) Malignant fibrous neoplasms of bone C400-C419 8810-8811, 8823, 8830 3 049 084
C000-C809 8812, 9262 3 049 084
(d.2) Malignant chordomas C000-C809 9370-9372 3 050 084
(d.3) Odontogenic malignant tumors C000-C809 9270-9275, 9280-9282, 9290, 9300-9302, 9310-9312, 9320-9322, 9330, 9340-9342 3 051 084
(d.4) Miscellaneous malignant bone tumors C000-C809 9250, 9261 3 052 084
(e) Unspecified malignant bone tumors C400-C419 8000-8005, 8800-8801, 8803-8805 3 053 085
IX. Soft tissue and other extraosseous sarcomas
(a) Rhabdomyosarcomas C000-C809 8900-8905, 8910, 8912, 8920, 8991 3 054 091
(b) Fibrosarcomas, peripheral nerve sheath tumors, and other fibrous neoplasms
(b.1) Fibroblastic and myofibroblastic tumors C000-C399, C440-C768, C809 8810-8811, 8813-8815, 8821, 8823, 8834-8835 3 055 092
C000-C809 8820, 8822, 8824-8827, 9150, 9160 3 055 092
(b.2) Nerve Sheath Tumors C000-C809 9540-9571 3 056 092
(b.3) Other fibromatous neoplasms C000-C809 9491, 9580 3 057 092
(c) Kaposi sarcoma C000-C809 9140 3 058 093
(d) Other specified soft tissue sarcomas
(d.1) Ewing tumor and Askin tumor of soft tissue C000-C399, C470-C759 9260 3 059 094
C000-C399, C470-C639, C659-C768, C809 9365 3 059 094
(d.2) pPNET of soft tissue C000-C399, C470-C639, C659-C699, C739-C768, C809 9364 3 060 094
(d.3) Extrarenal rhabdoid tumor C000-C639, C659-C699, C739-C768, C809 8963 3 061 094
(d.4) Liposarcomas C000-C809 8850-8858, 8860-8862, 8870, 8880-8881 3 062 094
(d.5) Fibrohistiocytic tumors C000-C399, C440-C768, C809 8830 3 063 094
C000-C809 8831-8833, 8836, 9251-9252 3 063 094
(d.6) Leiomyosarcomas C000-C809 8890-8898 3 064 094
(d.7) Synovial sarcomas C000-C809 9040-9044 3 065 094
(d.8) Blood vessel tumors C000-C809 9120-9125, 9130-9133, 9135-9136, 9141-9142, 9161, 9170-9175 3 066 094
(d.9) Osseous and chondromatous neoplasms of soft tissue C490-C499 9180, 9210, 9220, 9240 3 067 094
C000-C809 9231 3 067 094
(d.10) Alveolar soft parts sarcoma C000-C809 9581 3 068 094
(d.11) Miscellaneous soft tissue sarcomas C000-C809 8587, 8710-8713, 8806, 8840-8842, 8921, 8982, 8990, 9373 3 069 094
(e) Unspecified soft tissue sarcomas C000-C399, C440-C768, C809 8800-8805 3 070 095
X. Germ cell tumors, trophoblastic tumors, and neoplasms of gonads
(a) Intracranial and intraspinal germ cell tumors
(a.1) Intracranial and intraspinal germinomas C700-C729, C751-C753 9060-9065 0,1,3 071 101
(a.2) Intracranial and intraspinal teratomas C700-C729, C751-C753 9080-9084 0,1,3 072 101
(a.3) Intracranial and intraspinal embryonal carcinomas C700-C729, C751-C753 9070, 9072 0,1,3 073 101
(a.4) Intracranial and intraspinal yolk sac tumor C700-C729, C751-C753 9071 0,1,3 074 101
(a.5) Intracranial and intraspinal choriocarcinoma C700-C729, C751-C753 9100 0,1,3 075 101
(a.6) Intracranial and intraspinal tumors of mixed forms C700-C729, C751-C753 9085, 9101 0,1,3 076 101
(b) Malignant extracranial and extragonadal germ cell tumors
(b.1) Malignant germinomas of extracranial and extragonadal sites C000-C559, C570-C619, C630-C699, C739-C750, C754-C768, C809 9060-9065 3 077 102
(b.2) Malignant teratomas of extracranial and extragonadal sites C000-C559, C570-C619, C630-C699, C739-C750, C754-C768, C809 9080-9084 3 078 102
(b.3) Embryonal carcinomas of extracranial and extragonadal sites C000-C559, C570-C619, C630-C699, C739-C750, C754-C768, C809 9070, 9072 3 079 102
(b.4) Yolk sac tumor of extracranial and extragonadal sites C000-C559, C570-C619, C630-C699, C739-C750, C754-C768, C809 9071 3 080 102
(b.5) Choriocarcinomas of extracranial and extragonadal sites C000-C559, C570-C619, C630-C699, C739-C750, C754-C768, C809 9100, 9103-9104 3 081 102
(b.6) Other and unspecified malignant mixed germ cell tumors of extracranial and extragonadal sites C000-C559, C570-C619, C630-C699, C739-C750, C754-C768, C809 9085, 9101-9102, 9105 3 082 102
(c) Malignant gonadal germ cell tumors
(c.1) Malignant gonadal germinomas C569, C620-C629 9060-9065 3 083 103
(c.2) Malignant gonadal teratomas C569, C620-C629 9080-9084, 9090-9091 3 084 103
(c.3) Gonadal embryonal carcinomas C569, C620-C629 9070, 9072 3 085 103
(c.4) Gonadal yolk sac tumor C569, C620-C629 9071 3 086 103
(c.5) Gonadal choriocarcinoma C569, C620-C629 9100 3 087 103
(c.6) Malignant gonadal tumors of mixed forms C569, C620-C629 9085, 9101 3 088 103
(c.7) Malignant gonadal gonadoblastoma C569, C620-C629 9073 3 089 103
(d) Gonadal carcinomas C569, C620-C629 8010-8041, 8050-8075, 8082, 8120-8122, 8130-8141, 8143, 8190-8201, 8210-8211, 8221-8241, 8244-8246, 8260-8263, 8290, 8310, 8313, 8320, 8323, 8380-8384, 8430, 8440, 8480-8490, 8504, 8510, 8550, 8560-8573, 9000, 9014, 9015 3 090 104
C000-C809 8441-8444, 8450-8451, 8460-8473 3 090 104
(e) Other and unspecified malignant gonadal tumors C000-C809 8590-8671 3 091 105
C569, C620-C629 8000-8005 3 091 105
XI. Other malignant epithelial neoplasms and malignant melanomas
(a) Adrenocortical carcinomas C000-C809 8370-8375 3 092 111
(b) Thyroid carcinomas C739 8010-8041, 8050-8075, 8082, 8120-8122, 8130-8141, 8190, 8200-8201, 8211, 8230, 8231, 8244-8246, 8260-8263, 8290, 8310, 8320, 8323, 8430, 8440, 8480-8481, 8510, 8560-8573 3 093 112
C000-C809 8330-8337, 8340-8347, 8350 3 093 112
(c) Nasopharyngeal carcinomas C110-C119 8010-8041, 8050-8075, 8082-8083, 8120-8122, 8130-8141, 8190, 8200-8201, 8211, 8230-8231, 8244-8246, 8260-8263, 8290, 8310, 8320, 8323, 8430, 8440, 8480-8481, 8500-8576 3 094 113
(d) Malignant melanomas C000-C809 8720-8780, 8790 3 095 114
(e) Skin carcinomas C440-C449 8010-8041, 8050-8075, 8078, 8082, 8090-8110, 8140, 8143, 8147, 8190, 8200, 8240, 8246-8247, 8260, 8310, 8320, 8323, 8390-8420, 8430, 8480, 8542, 8560, 8570-8573, 8940, 8941 3 096 115
(f) Other and unspecified carcinomas
(f.1) Carcinomas of salivary glands C079-C089 8010-8084, 8120-8157, 8190-8264, 8290, 8310, 8313-8315, 8320-8325, 8360, 8380-8384, 8430-8440, 8452-8454, 8480-8586, 8588-8589, 8940-8941, 8983, 9000, 9010-9016, 9020, 9030 3 097 116
(f.2) Carcinomas of colon and rectum C180, C182-C189, C199, C209, C210-C218 8010-8084, 8120-8157, 8190-8264, 8290, 8310, 8313-8315, 8320-8325, 8360, 8380-8384, 8430-8440, 8452-8454, 8480-8586, 8588-8589, 8940-8941, 8983, 9000, 9010-9016, 9020, 9030 3 098 116
(f.3) Carcinomas of appendix C181 8010-8084, 8120-8157, 8190-8264, 8290, 8310, 8313-8315, 8320-8325, 8360, 8380-8384, 8430-8440, 8452-8454, 8480-8586, 8588-8589, 8940-8941, 8983, 9000, 9010-9016, 9020, 9030 3 099 116
(f.4) Carcinomas of lung C340-C349 8010-8084, 8120-8157, 8190-8264, 8290, 8310, 8313-8315, 8320-8325, 8360, 8380-8384, 8430-8440, 8452-8454, 8480-8586, 8588-8589, 8940-8941, 8983, 9000, 9010-9016, 9020, 9030 3 100 116
(f.5) Carcinomas of thymus C379 8010-8084, 8120-8157, 8190-8264, 8290, 8310, 8313-8315, 8320-8325, 8360, 8380-8384, 8430-8440, 8452-8454, 8480-8586, 8588-8589, 8940-8941, 8983, 9000, 9010-9016, 9020, 9030 3 101 116
(f.6) Carcinomas of breast C500-C509 8010-8084, 8120-8157, 8190-8264, 8290, 8310, 8313-8315, 8320-8325, 8360, 8380-8384, 8430-8440, 8452-8454, 8480-8586, 8588-8589, 8940-8941, 8983, 9000, 9010-9016, 9020, 9030 3 102 116
(f.7) Carcinomas of cervix uteri C530-C539 8010-8084, 8120-8157, 8190-8264, 8290, 8310, 8313-8315, 8320-8325, 8360, 8380-8384, 8430-8440, 8452-8454, 8480-8586, 8588-8589, 8940-8941, 8983, 9000, 9010-9016, 9020, 9030 3 103 116
(f.8) Carcinomas of bladder C670-C679 8010-8084, 8120-8157, 8190-8264, 8290, 8310, 8313-8315, 8320-8325, 8360, 8380-8384, 8430-8440, 8452-8454, 8480-8586, 8588-8589, 8940-8941, 8983, 9000, 9010-9016, 9020, 9030 3 104 116
(f.9) Carcinomas of eye C690-C699 8010-8084, 8120-8157, 8190-8264, 8290, 8310, 8313-8315, 8320-8325, 8360, 8380-8384, 8430-8440, 8452-8454, 8480-8586, 8588-8589, 8940-8941, 8983, 9000, 9010-9016, 9020, 9030 3 105 116
(f.10) Carcinomas of other specified sites C000-C069, C090-C109, C129-C179, C239-C339, C380-C399, C480-C488, C510-C529, C540-C549, C559, C570-C619, C630-C639, C659-C669, C680-C689, C700-C729, C750-C759 8010-8084, 8120-8157, 8190-8264, 8290, 8310, 8313-8315, 8320-8325, 8360, 8380-8384, 8430-8440, 8452-8454, 8480-8586, 8588-8589, 8940-8941, 8983, 9000, 9010-9016, 9020, 9030 3 106 116
(f.11) Carcinomas of unspecified site C760-C768, C809 8010-8084, 8120-8157, 8190-8264, 8290, 8310, 8313-8315, 8320-8325, 8360, 8380-8384, 8430-8440, 8452-8454, 8480-8586, 8588-8589, 8940-8941, 8983, 9000, 9010-9016, 9020, 9030 3 107 116
XII. Other and unspecified malignant neoplasms
(a) Other specified malignant tumors
(a.1) Gastrointestinal stromal tumor C000-C809 8936 3 108 121
(a.2) Pancreatoblastoma C000-C809 8971 3 109 121
(a.3) Pulmonary blastoma and pleuropulmonary blastoma C000-C809 8972-8973 3 110 121
(a.4) Other complex mixed and stromal neoplasms C000-C809 8930-8935, 8950-8951, 8974-8981 3 111 121
(a.5) Mesothelioma C000-C809 9050-9055 3 112 121
(a.6) Other specified malignant tumors C000-C809 9110 3 113 121
C000-C399, C470-C759 9363 3 113 121
(b) Other unspecified malignant tumors C000-C218, C239-C399, C420-C559, C570-C619, C630-C639, C659-C699, C739-C750, C754-C809 8000-8005 3 114 122

* This table was updated for Hematopoietic codes based on WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues (2008).
^ Subject to change based on evolving ICD-O-3 coding rules.