SEER Inquiry System - Question 20021046 Details

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Produced: 01/10/2026 10:16 PM

Question 20021046

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Inquiry Details

References:

SEER EOD-88, 3rd Ed, 152

Question:

Behavior Code/EOD-Extension--Bladder: If an in situ lesion of the urinary bladder involves the von Brunn nests, is it still in situ? See discussion.

Discussion:

Von Brunn nests: Compact, rounded aggregates of urothelial (transitional) cells in the lamina propria, with or without connection to the surface epithelium.

Urothelial (transitional cell) carcinoma in situ...may involve von Brunn nests...

Histologic Typing of Urinary Bladder Tumours, Second Edition, WHO, pp 12 & 21

Answer:

For cases diagnosed 1998-2003:

Code the Behavior Code and the EOD-Extension field according to the pathology report.

If the pathology report states the tumor to be noninvasive or in situ, whether or not von Brunn nests are involved, code behavior as 2 [in situ] and extension as in situ.

If the tumor is described as invasive and involves the von Brunn nests, code the EOD-Extension field to 15 [invasive tumor confined to subepithelial connective tissue] because code 15 includes extension to the lamina propria and von Brunn nests are within the lamina propria.

Cancer Site Category:

Bladder

Data Item Category:

Behavior

Other Category:

N/A

Year:

2002