SEER Inquiry System - Question 20051107 Details

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Question 20051107

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Inquiry Details

References:

#1: SEER*Rx. http://seer.cancer.gov/tools/s

#2: 2004 SEER Manual, 195. March 2006 update

Question:

Chemotherapy/Radiation Therapy--Lymphoma: How is treatment coded when Rituxan is given in combination with the monoclonal antibody Zevalin conjugated to 90-Yttrium or the monoclonal antibody Bexxar conjugated to 131-Iodine in the treatment of NHL?

Discussion:

Answer:

Code Rituxan as chemotherapy. Code 90-Yttrium as radioisotope. Code 131-Iodine as radioisotope when given with Rituxan as treatment for lymphoma.

Zevalin is a monoclonal antibody conjugated to Yttrium 90. Bexxar is a monoclonal antibody conjugated to Iodine 131. In both drugs, the monoclonal antibody is only the delivery agent for the radioisotope. Both drugs should be coded as radioisotopes. The one-two-three punch of Rituxan and zevalin followed by Rituxan and Bexxar should be coded as chemotherapy plus radioisotopes. Zevalin is also used by itself for people who have not responded to Rituxan.

Cancer Site Category:

Lymphoma

Data Item Category:

Chemotherapy, Radiation Therapy

Other Category:

N/A

Year:

2005