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Produced: 05/19/2026 12:43 PM
Question 20110014
Inquiry Details
References:
#1: ICD-O-3
#2: SINQ 20021168
Question:
MP/H Rules/Histology--Corpus Uteri: Which MP/H rule applies in coding histology for a "high grade endometrioid adenocarcinoma with squamous differentiation (adenosquamous carcinoma)"? See Discussion.
Discussion:
Is the pathology describing a specific histology, adenosquamous carcinoma [8560/3]? Or is this a combination/mixed histology code per rule H16? The Rule H16 instruction is to code a mixed histology code, 8323/3 [mixed cell adenocarcinoma] from Table 2 when two or more of the histologies are present (i.e., endometrioid and squamous in this case).
Answer:
For cases diagnosed 2007 or later:
Endometrioid adenocarcinoma with squamous differentiation is coded to 8570 [Adenocarcinoma with squamous metaplasia].
The following row needs to be added to Table 2 in order to be able to correctly use the MP/H rules to reach this conclusion.
Column 1: Endometrioid adenocarcinoma
Column 2: Squamous metaplasia
Squamous differentiation
Column 3: Adenocarcinoma with squamous metaplasia
Column 4: 8570
The change will be made in the next revision of the rules.
Cancer Site Category:
Corpus uteri
Data Item Category:
Histology
Other Category:
N/A
Year:
2011
