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SEER Inquiry System - Report
Produced: 11/27/2024 4:56 AM
Question 20110055
Inquiry Details
References:
Heme & Lymph Manual & DB
Question:
Multiple primaries--Heme & Lymphoid Neoplasms: How many primaries are to be abstracted for a bone marrow biopsy diagnosis of "acute myeloid leukemia (non-M3 type; favor FAB M1), probably arising in myelodysplastic syndrome;" and flow cytometry studies performed the same day were consistent with acute myeloid leukemia?
Discussion:
Answer:
For cases diagnosed 2010 and forward, access the Hematopoietic Database at http://seer.cancer.gov/seertools/hemelymph.
Ambiguous terminology is NOT used to determine histology for hematopoietic or lymphoid neoplasms. Therefore, the comment that the AML is "probably" arising in myelodysplastic syndrome is not used to determine the histology code. The term "favor" is also an ambiguous term and cannot be used to code histology.
This is a single histology per M2, abstract a single primary when there is a single histology. The histology is coded to 9861/3 [acute myeloid leukemia, NOS]
SEER*Educate provides training on how to use the Heme Manual and DB. If you are unsure how to arrive at the answer in this SINQ question, refer to SEER*Educate to practice coding hematopoietic and lymphoid neoplasms. Review the step-by-step instructions provided for each case scenario to learn how to use the application and manual to arrive at the answer provided. https://educate.fhcrc.org/LandingPage.aspx.
History:
This SINQ question has been updated to the Hematopoietic & Lymphoid Neoplasm Manual & Database published January 2014.
The original answer below was written based on the rules in 2010
For cases diagnosed 2010-2011, access the Hematopoietic Database at http://seer.cancer.gov/tools/heme/. Click on Hematopoietic Project. Click on Hematopoietic and Lymphoid Database. For 2010-2011 diagnoses, click on the "use the 2010 database" label in the upper right corner of the screen. The 2010 Hematopoietic Coding Manual (PDF) button will appear to indicate the correct version of the program is available now for query.
This is a single primary, acute myeloid leukemia without maturation [9873/3]. FAB M1 is an older term for acute myeloid leukemia without maturation. Ambiguous terminology is NOT used to determine histology for hematopoietic or lymphoid neoplasms, so the comment that the AML is "probably" arising in myelodysplastic syndrome is not used to determine the histology code. The steps used to arrive at this decision are:
Recognize that you cannot use ambiguous terminology to code histology. As a result you have a single histology to code.
Enter in the Heme DB to search for the histology code. Click the SEARCH button. The term "acute myeloid leukemia without maturation" [9873/3]" is highlighted on the screen under the RESULTS FOR ALL TERMS area.
Check the ALTERNATIVE NAMES section. FAB M1 is synonymous with acute myeloid leukemia, M1.
Check the DEFINITIVE DIAGNOSTIC METHODS section. It indicates that a bone marrow biopsy and immunophenotyping are the diagnostic methods. Per the bone marrow biopsy, the diagnosis is AML, M1 [9873/3].
