SEER Inquiry System - Question 20140004 Details

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SEER Inquiry System - Report

Produced: 04/29/2025 11:13 AM

Question 20140004

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Inquiry Details

References:

2013 SEER Manual

Question:

Grade--Liver: How should grade be coded for a liver lesion treated with radio frequency ablation (RFA) followed by a transplant showing moderately differentiated hepatocellular carcinoma? See discussion.

Discussion:

The SEER Manual emphasizes the importance of coding grade only prior to neoadjuvant treatment as systemic treatment and radiation can alter a tumor's grade. This patient did not have neoadjuvant chemotherapy or radiation, but did undergo a prior surgical procedure (RFA) in an attempt to destroy tumor tissue. The subsequent transplant showed residual moderately differentiated HCC.

Answer:

For this case, record the grade specified even though it is after RFA. RFA is not systemic or radiation treatment and should not alter the grade.

Cancer Site Category:

N/A

Data Item Category:

N/A

Other Category:

N/A

Year:

2014