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SEER Inquiry System - Report
Produced: 09/29/2025 3:25 PM
Question 20160040
Inquiry Details
References:
#1: ICD-O-3
#2: NAACCR Implementation Guidelines, 3. 2017
Question:
Reportability--Thyroid: Is a final diagnosis of "non-invasive follicular thyroid neoplasm with papillary-like nuclear features" (NIFTP) reportable when the diagnosis comment states this tumor was historically classified as encapsulated follicular variant of papillary thyroid carcinoma? See Discussion.
Discussion:
The term "non-invasive follicular thyroid neoplasm with papillary-like nuclear features" is now being used, instead of the previous classification of an encapsulated malignant thyroid tumor. Recent evidence supports a very minimal risk of aggressive behavior for these tumors, and pathologists in our area are no longer classifying these as malignant in the final diagnosis.
Answer:
As of January 1, 2021
Non-invasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP) C739 is no longer reportable for cases diagnosed 1/1/2021 forward. See the ICD-O-3.2 material on the NAACCR website,https://www.naaccr.org/icdo3/#1582820761121-27c484fc-46a7
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Answer for cases diagnosed 1-1-2017 to 12/31/2020
Report NIFTP and assign ICD-O-3 morphology code 8343/2. See the NAACCR document, page 3, https://20tqtx36s1la18rvn82wcmpn-wpengine.netdna-ssl.com/wp-content/uploads/2017/01/What-You-Need-to-Know-for-2017.pdf
History:
For cases diagnosed prior to 1-1-2017
We are discussing this terminology change with the other standard setters and with the ICD-O-3 Implementation Workgroup. When a consensus decision is made, it will be reflected in the revised MP/H (to be known as Solid Tumor) rules.
For now, you can report noninvasive follicular thyroid neoplasm with papillary-like nuclear features as a synonym for encapsulated follicular variant of papillary thyroid carcinoma and assign 8340/3. Document this in a text field.
