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SEER Inquiry System - Report
Produced: 11/25/2024 4:29 PM
Question 20170028
Inquiry Details
References:
#1: 2007 MP/H Rules. Kidney
#2: ICD-O-3
Question:
MP/H Rules/Histology--Kidney: How should histology be coded for a clear cell renal cell carcinoma when the CAP protocol indicates sarcomatoid features are present? See Discussion.
Discussion:
Sarcomotoid (8318) is listed as a specific renal cell subtype in the MP/H manual, but it is not listed as a renal cell subtype in the most recent WHO blue book for Urinary Organs. We are wondering if sarcomatoid features, as listed in the CAP protocol format in the following example, should be ignored when coding histology?
Left kidney, radical nephrectomy:
Clear cell renal cell carcinoma, with the following features:
Tumor size: 8.5 X 6 cm.
Tumor focality: Unifocal.
Macroscopic extent of tumor: Tumor limited to kidney.
Sarcomatoid features: Present (<20% of tumor shows sarcomatoid features).
Histologic grade: G4.
Microscopic tumor extension: Tumor limited to kidney.
Margins: All margins negative for invasive carcinoma.
Lymph-vascular invasion: Not identified.
Answer:
Code 8255 (adenocarcinoma with mixed subtypes). The Multiple Primaries/Histology Rule H6 applies as there are two or more specific renal cell carcinoma types, clear cell and sarcomatoid (Spindle cell), as listed in Table 1 of the kidney Terms and definitions.
