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SEER Inquiry System - Report
Produced: 05/11/2026 3:44 AM
Question 20180002
Inquiry Details
References:
#1: 2007 MP/H Rules. Urinary
#2: MP/H Training, Beyond the Basics. Slide 6, General Instructions
Question:
MP/H Rules/Multiple primaries--Urinary: Is a renal pelvis diagnosed 5/2016 a separate primary when the first invasive bladder was 12/2011? Per rule M7, the 5/2016 renal pelvis is more than 3 years later. Does Multiple Primary/Histology (MP/H) rule M7 refer back to the original diagnosis date or to the last occurrence? See Discussion.
Discussion:
12/30/11 Bladder Biopsy: Diffuse carcinoma in situ of bladder, urothelial cancer at trigone (Stage T1)
1/30/2012 Transurethral resection of the bladder was non-papillary, urothelial carcinoma, focal invasion of lamina propria, staged T1
11/10/14, 9/28/15, 9/26/16, 10/19/17 all had positive bladder cytology of urothelial carcinoma
5/16/16 Left renal pelvis aspirate: positive for malignant cells, urothelial carcinoma
9/26/16 Left renal pelvis aspirate: positive for malignant cells, urothelial carcinoma
10/18/16-11/7/16 Bacillus Calmette-Guerin (BCG) x3 administered into the renal collecting system via ureteral catheter
Answer:
For cases diagnosed prior to 2018
This case is a single primary. This patient has not had a disease-free interval as demonstrated by the positive cytologies from 2014 through 2017. The MP/H rules cannot be applied in this case.
To answer your question about the timing of rule M7, please see slide 6 in the Beyond the Basics MP/H advanced training, General Instructions, https://seer.cancer.gov/tools/mphrules/training_adv/SEER_MPH_Gen_Instruc_06152007.pdf
