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SEER Inquiry System - Report
Produced: 07/22/2025 12:07 AM
Question 20210011
Inquiry Details
References:
ICD-O-3
Question:
Primary site: Is C720 the correct primary site for a diagnosis of a paraspinal neuroblastoma on autopsy in a nine month old with Noonan syndrome? See Discussion.
Discussion:
Autopsy/Pathology Report (2020) excerpts
External Examination
Nervous System: There is an 8.5 cm mass located in the right thoracic paraspinal area.
Final Anatomic Diagnosis
Clinical History: Paraspinal mass suspicious for neuroblastic tumor (detected by imaging studies)
Nervous System: Right thoracic paraspinal neuroblastoma, poorly differentiated
Answer:
Assign primary site code C473 for this case based on the information provided (peripheral nerves and autonomic nervous system of thorax).
From our expert pathologist consultant: The origin of neuroblastomas is generally in the adrenal medulla or one of the sympathetic ganglia on either side of the vertebral column (although they have been reported in many other locations given the migration of the neural crest cells embryologically).
