SEER Inquiry System - Report
Produced: 03/29/2025 1:17 AM
Question 20250008
Inquiry Details
References:
#1: Heme & Lymph Manual & DB, 18-21. November 2024, Diagnostic Confirmation
#2: 2025 SEER Manual, 118-120. Diagnostic Confirmation
Question:
Diagnostic Confirmation--Heme & Lymphoid Neoplasms: How is Diagnostic Confirmation coded for hematopoietic and lymphoid neoplasms (heme) when immunophenotyping, genetics, etc. confirm the diagnosis.
Discussion:
Answer:
Assign Code 3 (Positive histology PLUS positive immunophenotyping or genetic testing) for
1. Cases with positive histology for the neoplasm being abstracted (including acceptable ambiguous terminology and provisional diagnosis), ANDÂ
- Immunophenotyping, genetic testing, or JAK2 is listed in the Definitive Diagnosis in the Heme Database, AND
- Testing
- Confirms the neoplasm OR
- Identifies a more specific histology (not preceded by ambiguous terminology)
- Peripheral blood smear followed by flow cytometry (most commonly done with CLL/SLL, 9823/3)
2. A not otherwise specified (NOS) histology diagnosed and not a provisional diagnosis, AND genetic/immunophenotyping was performed and positive
Refer to the current version of the Heme Manual for specific notes and examples when coding Diagnostic Confirmation.