Rare Cancer Classification

Starting with the 1975-2018 SEER Research Data (November 2020 submission), the Rare Cancer classification variable is available. The list of rare cancers was developed by the Surveillance of Rare Cancer in Europe (RARECARE) ⁽¹⁾ to include clinically relevant, histologically defined rare cancers with an annual crude incidence rate smaller than 6 per 100,000. The original list of rare cancers was recently revised and applied to the European data and the SEER data, and is now available in SEER*Stat ⁽²⁾. The rare cancer list is organized into 2 tiers. The bottom tier (tier 2) includes rare cancers that are considered similar from the point of view of clinical management and research. The tier 2 rare cancers are then further grouped into more general categories of tumors (tier 1), considered to involve the same clinical expertise and patient referral structure. Only a few tier 1 tumors are rare and some are not sub-classified into tier 2.

The information provided in this table is also available to download (XLSX, 39 KB).

Tumor	Primary Site	ICD-O-3 Morphology Code	Behavior	Recode
1. Epithelial Tumors of Nasal Cavity and Sinuses
1.1 Squamous cell carcinoma with variants of nasal cavity and sinuses	C30.0, C31	8004, 8023, 8032, 8050-8052, 8070-8076, 8078, 8083-8084, 8120-8123, 8130, 8560, 8980	0-3	01
1.2 Lymphoepithelial carcinoma of nasal cavity and sinuses	C30.0, C31	8082	0-3	02
1.3 Undifferentiated carcinoma of nasal cavity and sinuses	C30.0, C31	8020-8022	0-3	03
1.4 Intestinal type adenocarcinoma of nasal cavity and sinuses	C30.0, C31	8144	0-3	04
1.5 Other epithelial tumors of nasal cavity and sinuses^*	C30.0, C31	8000-8001, 8003, 8010-8012, 8030-8031, 8033-8034, 8046	0-3	05
2. Epithelial Tumors of Nasopharynx
2.1 Squamous cell carcinoma with variants of nasopharynx	C11	8004, 8020-8022, 8032, 8051-8052, 8070-8076, 8078, 8082-8084, 8120-8123, 8560, 8980	0-3	06
2.2 Papillary adenocarcinoma of nasopharynx	C11	8050, 8260	0-3	07
2.3 Other epithelial tumors of nasopharynx^*	C11	8000-8001, 8010-8012, 8030, 8033-8034, 8046, 8145	0-3	08
3. Epithelial Tumors of Major Salivary Glands and Salivary-gland Type Tumors
3.1 Epithelial tumor of major salivary glands	C07, C08	8000-8001, 8003-8005, 8010-8012, 8014-8015, 8020-8022, 8030-8035, 8046, 8050-8052, 8070-8076, 8078, 8082-8084, 8120-8123, 8130, 8140-8141, 8143-8144, 8147, 8190, 8200-8201, 8211, 8230-8231, 8255, 8260-8263, 8290, 8310, 8320, 8323, 8401, 8410, 8430, 8440, 8450, 8480-8481, 8490, 8500, 8502, 8504, 8510, 8525, 8550-8551, 8560-8562, 8570, 8574-8575, 8940-8941, 8951, 8980-8982	0-3	09
3.2 Salivary gland type tumor of head and neck	C00-C06, C09-C14, C30.0, C31-C32	8140-8141, 8143, 8147, 8190, 8200-8201, 8211, 8230-8231, 8261, 8263, 8290, 8310, 8320, 8323, 8401, 8430, 8440, 8450, 8480-8481, 8490, 8500, 8504, 8510, 8525, 8550-8551, 8562, 8570, 8574, 8675, 8941, 8982	0-3	10
3.2 Salivary gland type tumor of head and neck	C00-C06, C09-C14, C32	8144	0-3	10
4. Epithelial Tumors of Hypopharynx and Larynx
4.1 Squamous cell carcinoma with variants of hypopharynx	C12, C13	8004, 8020-8022, 8031-8032, 8050-8052, 8070-8076, 8078, 8082-8084, 8120, 8123, 8560, 8980	0-3	11
4.2 Squamous cell carcinoma with variants of larynx	C32	8004, 8020-8022, 8031-8032, 8050-8052, 8070-8076, 8078, 8082-8084, 8120, 8123, 8560, 8980	0-3	12
4.3 Other epithelial tumors of hypopharynx and larynx^*	C12, C13, C32	8000-8001, 8003, 8005, 8010-8012, 8030, 8033, 8035, 8951	0-3	13
5. Epithelial Tumors of Oropharynx
5.1 Squamous cell carcinoma with variants of oropharynx	C01.9, C02.4, C02.8, C05.1-C05.2, C05.8-C05.9, C09.0-C10.4, C10.8-10.9, C14.2	8004, 8020-8022, 8032, 8050-8052, 8070-8076, 8078, 8082-8086, 8120-8121, 8123, 8560, 8980	0-3	14
5.2 Other epithelial tumors of oropharynx^*	C01.9, C02.4, C02.8, C05.1-C05.2, C05.8-C05.9, C09.0-C10.4, C10.8-10.9, C14.2	8000-8001, 8003, 8005, 8010-8012, 8030-8031, 8033, 8951	0-3	15
6. Epithelial Tumors of Oral Cavity and Lip
6.1 Squamous cell carcinoma with variants of oral cavity	C02.0-C02.3, C02.9, C03.0-C05.0, C06.0-C06.9	8004, 8020-8022, 8032, 8050-8052, 8070-8076, 8078, 8082-8084, 8123, 8560, 8980	0-3	16
6.2 Squamous cell carcinoma with variants of lip	C00.0-C00.9	8004, 8032, 8050-8052, 8070-8076, 8078, 8082-8084, 8090-8095, 8097, 8110, 8390, 8400, 8407, 8410, 8560, 8980	0-3	17
6.3 Other epithelial tumors of oral cavity and lip^*	C02.0-C02.3, C02.9, C03.0-C05.0, C06.0-C06.9	8000-8001, 8003, 8010-8012, 8015, 8030-8031, 8033-8034, 8951, 8981	0-3	18
7. Epithelial Tumors of Esophagus
7.1 Squamous cell carcinoma with variants of esophagus	C15	8004, 8032, 8050-8052, 8070-8076, 8078, 8082-8084, 8123, 8560, 8980	0-3	19
7.2 Adenocarcinoma with variants of esophagus	C15	8140-8145, 8147, 8190, 8201, 8210-8211, 8221, 8230-8231, 8255, 8260-8263, 8290, 8310, 8315, 8320, 8323, 8333, 8380-8384, 8401, 8440-8441, 8450, 8480-8482, 8490, 8500, 8503-8504, 8510, 8512, 8514, 8525, 8542, 8551, 8570-8576	0-3	20
7.3 Salivary gland type tumor of esophagus	C15	8200, 8430, 8550, 8562	0-3	21
7.4 Undifferentiated carcinoma of esophagus	C15	8020-8022	0-3	22
7.5 Other epithelial tumors of esophagus^*	C15	8000-8001, 8003, 8010-8012, 8030-8031, 8033, 8035	0-3	23
8. Epithelial Tumors of Stomach
8.1 Adenocarcinoma with variants of stomach	C16	8050, 8140-8145, 8147, 8190, 8201, 8210-8211, 8214, 8221, 8230-8231, 8255, 8260-8263, 8290, 8310, 8315, 8320, 8323, 8333, 8380-8384, 8401, 8440-8441, 8450, 8480-8482, 8490, 8500, 8503-8504, 8510, 8512, 8514, 8525, 8542, 8550-8551, 8560, 8562, 8570-8576	0-3	24
8.2 Squamous cell carcinoma with variants of stomach	C16	8004, 8032, 8051-8052, 8070-8076, 8078, 8082-8084, 8980	0-3	25
8.3 Salivary gland-type tumor of stomach	C16	8200, 8430	0-3	26
8.4 Undifferentiated carcinoma of stomach	C16	8020-8022	0-3	27
8.5 Other epithelial tumors of stomach^*	C16	8000-8001, 8003, 8005, 8010-8012, 8030-8031, 8033, 8035, 8040, 8122-8123, 8130, 8951	0-3	28
9. Epithelial Tumors of Small Intestine
9.1 Adenocarcinoma with variants of small intestine	C17	8020-8022, 8140-8141, 8143-8145, 8147, 8190, 8200-8201, 8210-8211, 8221, 8230-8231, 8255, 8260-8263, 8290, 8310, 8315, 8320, 8323, 8333, 8380-8384, 8401, 8430, 8440-8441, 8450, 8480-8482, 8490, 8500, 8503-8504, 8510, 8512, 8514, 8525, 8542, 8550-8551, 8560, 8562, 8570-8576	0-3	29
9.2 Squamous cell carcinoma with variants of small intestine	C17	8004, 8032, 8050-8052, 8070-8076, 8078, 8082-8084, 8980	0-3	30
9.3 Other epithelial tumors of small intestine^*	C17	8000-8001, 8003, 8010-8012, 8030-8031, 8033-8034, 8220, 8951	0-3	31
10. Epithelial Tumors of Colon (including appendix)
10.1 Adenocarcinoma with variants of colon	C18, C19	8020-8022, 8140-8141, 8143, 8147, 8190, 8201, 8210-8211, 8213, 8220-8221, 8230-8231, 8255, 8260-8263, 8265, 8290, 8310, 8315, 8320, 8323, 8333, 8380-8384, 8401, 8430, 8440-8441, 8450, 8482, 8490, 8500, 8503-8504, 8510, 8512, 8514, 8525, 8542, 8550-8551, 8560, 8562, 8571-8576	0-3	32
10.1 Adenocarcinoma with variants of colon	C18.0, C18.2-C18.9, C19	8480-8481	0-3	32
10.2 Squamous cell carcinoma with variants of colon	C18, C19	8004, 8032, 8050-8052, 8070-8076, 8078, 8082-8084, 8980	0-3	33
10.3 Fibromixoma and low grade mucinous adenocarcinoma of the appendix	C18.1	8480-8481	0-3	34
10.4 Other epithelial tumors of colon (including appendix)^*	C18, C19	8000-8001, 8003, 8005, 8010-8012, 8040, 8951	0-3	35
11. Epithelial Tumors of Rectum
11.1 Adenocarcinoma with variants of rectum	C20	8020-8022, 8140-8141, 8143-8145, 8147, 8190, 8200-8201, 8210-8211, 8213, 8220-8221, 8230-8231, 8255, 8260-8263, 8265, 8290, 8310, 8315, 8320, 8323, 8333, 8380-8384, 8401, 8430, 8440-8441, 8450, 8480-8482, 8490, 8500, 8503-8504, 8510, 8512, 8514, 8525, 8542, 8550-8551, 8560, 8562, 8570-8576	0-3	36
11.2 Squamous cell carcinoma with variants of rectum	C20	8004, 8032, 8050-8052, 8070-8076, 8078, 8082-8084, 8094, 8120-8124, 8130, 8980	0-3	37
11.3 Other epithelial tumors of rectum^*	C20	8000-8001, 8003, 8010-8012, 8030-8031, 8033, 8040, 8951	0-3	38
12. Epithelial Tumors of Anal Canal
12.1 Squamous cell carcinoma with variants of anal canal	C21	8004, 8020-8022, 8032, 8050-8052, 8070-8076, 8078, 8082-8084, 8095, 8120, 8122-8124, 8980	0-3	39
12.2 Adenocarcinoma with variants of anal canal	C21	8140-8141, 8143-8144, 8147, 8190, 8200-8201, 8210-8211, 8213, 8215, 8221, 8230-8231, 8255, 8260-8263, 8290, 8310, 8315, 8320, 8323, 8333, 8380-8384, 8401, 8430, 8440-8441, 8450, 8480-8482, 8490, 8500, 8503-8504, 8510, 8512, 8514, 8525, 8550-8551, 8560, 8562, 8570-8576	0-3	40
12.3 Pagets disease of anal canal	C21	8542	0-3	41
12.4 Other epithelial tumors of anal canal^*	C21	8000-8001, 8010-8012, 8014, 8033, 8081, 8090, 8094	0-3	42
13. Epithelial Tumors of Pancreas
13.1 Adenocarcinoma with variants of pancreas	C25	8010, 8020-8022, 8140-8141, 8143-8145, 8147, 8190, 8200-8201, 8210-8211, 8221, 8230-8231, 8255, 8260-8263, 8290, 8310, 8315, 8320, 8323, 8333, 8380-8384, 8401, 8430, 8440, 8450, 8471, 8480-8482, 8490, 8500, 8503-8504, 8510, 8512, 8514, 8521, 8523, 8525, 8542, 8560, 8562, 8570-8576, 8941	0-3	43
13.2 Squamous cell carcinoma with variants ofpancreas	C25	8004, 8032, 8050-8052, 8070-8076, 8078, 8082-8084, 8980	0-3	44
13.3 Acinar cell carcinoma of pancreas	C25	8550-8551	0-3	45
13.4 Mucinous cystadenocarcinoma of pancreas (invasive)	C25	8470	0-3	46
13.5 Intraductal papillary mucinous carcinoma invasive of pancreasl	C25	8453	0-3	47
13.6 Solid pseudopapillary carcinoma of pancreas	C25	8452	0-3	48
13.7 Serous cystadenocarcinoma of pancreas	C25	8441	0-3	49
13.8 Carcinoma with osteoclast-like giant cells ofpancreas	C25	8035	0-3	50
13.9 Other epithelial tumors ofpancreas^*	C25	8000-8001, 8003, 8005, 8011-8012, 8030-8031, 8033-8034, 8040, 8552	0-3	51
14. Epithelial Tumors of Liver and Intrahepatic Bile Tract (IBT)
14.1 Hepatocellular carcinoma of Liver and IBT	C22	8170, 8172-8175	0-3	52
14.1 Hepatocellular carcinoma of Liver and IBT	C22, C23.9, C24	8180	0-3	52
14.2 Hepatocellular carcinoma, fibrolamellar	C22	8171	0-3	53
14.3 Cholangiocarcinoma of IBT	C22	8160	0-3	54
14.4 Adenocarcinoma with variants of liver and IBT	C22	8140-8141, 8143, 8147, 8162, 8190, 8201, 8210-8211, 8221, 8230-8231, 8255, 8260-8263, 8290, 8310, 8315, 8320, 8323, 8333, 8380-8384, 8430, 8440-8441, 8450, 8480-8482, 8490, 8500, 8503-8504, 8510, 8512, 8514, 8525, 8542, 8550-8551, 8560, 8562, 8571-8576	0-3	55
14.5 Undifferentiated carcinoma of liver and IBT	C22	8020-8022	0-3	56
14.6 Squamous cell carcinoma with variants of liver and IBT	C22	8004, 8032, 8050-8052, 8070-8076, 8078, 8082-8084, 8980	0-3	57
14.7 Bile duct cystadenocarcinoma of IBT	C22	8161	0-3	58
14.8 Other epithelial tumors of liver and intrahepatic bile tract (IBT)^*	C22	8000-8001, 8003, 8010-8012, 8030-8031, 8033-8034, 8981	0-3	59
15. Epithelial Tumors of Gallbladder and Extrahepatic Biliary Tract (EBT)
15.1 Adenocarcinoma with variants of gallbladder	C23.9	8020-8022, 8050, 8140-8141, 8143-8144, 8147, 8160-8162, 8190, 8200-8201, 8210-8211, 8221, 8230-8231, 8255, 8260-8263, 8290, 8310, 8315, 8320, 8323, 8333, 8380-8384, 8430, 8440-8441, 8450, 8470, 8480-8482, 8490, 8500, 8503-8504, 8510, 8512, 8514, 8525, 8542, 8550-8551, 8560, 8562, 8570-8576	0-3	60
15.2 Adenocarcinoma with variants of EBT	C24	8020-8022, 8050, 8140-8141, 8143-8144, 8147, 8160-8163, 8190, 8200-8201, 8210-8211, 8220-8221, 8230-8231, 8255, 8260-8263, 8290, 8310, 8315, 8320, 8323, 8333, 8380-8384, 8430, 8440-8441, 8450, 8470, 8480-8482, 8490, 8500, 8503-8504, 8510, 8512, 8514, 8525, 8542, 8550-8551, 8560, 8562, 8570-8576	0-3	61
15.3 Squamous cell carcinoma of gallbladder and EBT	C23.9, C24	8004, 8032, 8051-8052, 8070-8076, 8078, 8082-8084, 8980	0-3	62
15.4 Other epithelial tumors of gallbladder and extrahepatic biliary tract (EBT)	C23.9, C24	8000-8001, 8003, 8005, 8010-8012, 8014-8015, 8030-8031, 8033, 8035, 8053-8069, 8145	0-3	63
16. Epithelial Tumors of Trachea
16.1 Squamous cell carcinoma with variants of trachea	C33	8004, 8020-8022, 8031-8032, 8050-8052, 8070-8076, 8078, 8082-8084, 8560, 8980	0-3	64
16.2 Adenocarcinoma with variants of trachea	C33	8140-8141, 8143-8144, 8147, 8190, 8201, 8210-8211, 8221, 8230-8231, 8255, 8260-8263, 8290, 8310, 8315, 8320, 8323, 8333, 8380-8384, 8440-8441, 8470, 8480-8482, 8490, 8504, 8510, 8512, 8514, 8525, 8542, 8550-8551, 8562, 8570-8576	0-3	65
16.3 Salivary gland type tumor of trachea	C33	8200, 8430, 8982	0-3	66
16.4 Other epithelial tumors of trachea^*	C33	8000-8001, 8010-8012, 8033, 8046	0-3	67
17. Epithelial Tumors of Lung
17.1 Squamous cell carcinoma with variants of lung	C34	8015, 8050-8052, 8070-8073, 8075-8076, 8078, 8082-8084, 8123	0-3	68
17.2 Adenocarcinoma with variants of lung	C34	8140-8141, 8143-8144, 8147, 8190, 8201, 8210-8211, 8221, 8230-8231, 8250-8257, 8260-8263, 8265, 8290, 8310, 8315, 8320, 8323, 8333, 8380-8384, 8401, 8440-8441, 8460, 8470, 8480-8482, 8490, 8504, 8510, 8512, 8514, 8525, 8542, 8550-8551, 8570-8576	0-3	69
17.3 Adenosquamous carcinoma of lung	C34	8560	0-3	70
17.4 Large cell carcinoma of lung	C34	8012, 8014, 8034	0-3	71
17.5 Poorly differentiated endocrine carcinoma of lung	C34	8002, 8013, 8041-8045, 8246	0-3	72
17.6 Salivary gland type tumor of lung	C34	8200, 8430, 8562, 8982	0-3	73
17.7 Sarcomatoid carcinoma of lung	C34	8004, 8022, 8030-8033, 8074, 8972, 8980	0-3	74
17.8 Other epithelial tumors of lung^*	C34	8000-8001, 8003, 8005, 8010-8011, 8020-8021, 8023, 8035, 8040, 8046, 8120, 8146, 8951, 8981	0-3	75
18. Epithelial Tumors of Thymus
18.1 Malignant thymoma	C37, C38.1, C38.3	8580-8586	0-3	76
18.2 Squamous cell carcinoma of thymus	C37	8046, 8050-8052, 8070-8076, 8078, 8083-8084, 8123	0-3	77
18.3 Adenocarcinoma with variants of thymus	C37	8020-8022, 8082, 8140-8141, 8143-8144, 8147, 8190, 8200-8201, 8210-8211, 8221, 8230-8231, 8255, 8260-8263, 8290, 8310, 8315, 8320, 8323, 8333, 8380-8384, 8430, 8440-8441, 8480-8482, 8490, 8504, 8510, 8512, 8514, 8525, 8542, 8550-8551, 8560, 8562, 8570-8576	0-3	78
18.4 Other epithelial tumors of thymus^*	C37	8000-8001, 8003-8004, 8010-8012, 8032-8033, 8588-8589, 8980	0-3	79
19. Epithelial Tumors of Breast
19.1 Inv carcinoma of no special type-NST (obs Invasive ductal carc of breast)	C50	8035, 8500-8501, 8507, 8514, 8521-8523	0-3	80
19.2 Invasive lobular carcinoma of breast	C50	8022, 8520, 8524	0-3	81
19.3 Mammary Pagets disease of breast	C50	8540-8541, 8543	0-3	82
19.4 Special types of adenocarcinoma of breast	C50	8050, 8201, 8211, 8260, 8290, 8314-8315, 8401, 8410, 8480-8481, 8502-8503, 8510, 8513	0-3	83
19.5 Metaplastic carcinoma of breast	C50	8015, 8032, 8070, 8560, 8570-8572, 8575	0-3	84
19.6 Salivary gland type tumor of breast	C50	8200, 8430, 8550, 8982	0-3	85
19.7 Other epithelial tumors of breast^*	C50	8000-8001, 8003-8005, 8010-8012, 8020-8021, 8030-8031, 8033, 8140-8141, 8143, 8145, 8147, 8190, 8210, 8221, 8230-8231, 8255, 8261-8263, 8310, 8320, 8323, 8333, 8440, 8490, 8504-8505, 8508, 8512, 8525, 8530, 8551, 8562, 8573-8574, 8576, 8951, 8980, 8983	0-3	86
20. Epithelial Tumors of Corpus Uteri
20.1 Adenocarcinoma with variants of corpus uteri	C54, C57.4	8050-8051, 8120, 8122-8123, 8130, 8140-8141, 8143-8144, 8147, 8190, 8201, 8210-8211, 8221, 8230-8231, 8255, 8260-8263, 8290, 8313, 8315, 8320, 8323, 8333, 8380-8384, 8401, 8430, 8440, 8470-8471, 8480-8482, 8490, 8503-8504, 8510, 8512, 8514, 8525, 8542, 8550-8551, 8560, 8562, 8570-8576, 9000, 9110	0-3	87
20.2 Squamous cell carcinoma with variants of corpus uteri	C54, C57.4	8052, 8070-8076, 8078, 8082-8084	0-3	88
20.3 Adenoid cystic carcinoma of corpus uteri	C54, C57.4	8200	0-3	89
20.4 Clear cell adenocarcinoma, NOS	C54, C57.4	8310	0-3	90
20.5 Serous (papillary) carcinoma	C54, C57.4	8441, 8450, 8460	0-3	91
20.6 Mullerian mixed tumor	C54, C57.4	8950-8951, 8980-8981	0-3	92
20.7 Other epithelial tumors of corpus uteri^*	C54, C57.4	8000-8001, 8003-8005, 8010-8012, 8014-8015, 8020-8022, 8030-8033	0-3	93
21. Epithelial Tumors of Cervix Uteri
21.1 Squamous cell carcinoma with variants of cervix uteri	C53	8015, 8050-8052, 8070-8076, 8078, 8082-8084, 8120, 8123, 8130	0-3	94
21.2 Adenocarcinoma with variants of cervix uteri	C53	8098, 8140-8141, 8143-8144, 8147, 8190, 8200-8201, 8210-8211, 8221, 8230-8231, 8255, 8260-8263, 8290, 8310, 8315, 8320, 8323, 8333, 8380-8384, 8410, 8430, 8440-8441, 8460, 8480-8482, 8490, 8504, 8510, 8512, 8514, 8525, 8542, 8550-8551, 8562, 8570-8576, 9110	0-3	95
21.3 Undifferentiated carcinoma of cervix uteri	C53	8020-8022	0-3	96
21.4 Mullerian mixed tumor of cervix uteri	C53	8950-8951, 8980	0-3	97
21.5 Other epithelial tumors of cervix uteri^*	C53	8000-8001, 8003-8005, 8010-8012, 8030-8033, 8560	0-3	98
22. Epithelial Tumors of Ovary and Falloppian Tubei
22.1 Adenocarcinoma with variants of ovary	C56.9	8050, 8120, 8122-8123, 8130, 8140-8141, 8143, 8146-8147, 8190, 8200-8201, 8210-8211, 8221, 8230-8231, 8255, 8260-8263, 8290, 8313, 8315, 8320, 8323, 8330, 8333, 8380-8384, 8401, 8430, 8440-8441, 8450, 8452-8453, 8460-8461, 8463, 8500, 8504, 8510, 8512, 8514, 8525, 8542, 8550-8551, 8562, 8570-8576, 9000, 9014-9015, 9110	0-3	99
22.2 Mucinous adenocarcinoma of ovary	C56.9	8470-8471, 8480-8482, 8490	0-3	100
22.3 Clear cell adenocarcinoma of ovary	C56.9	8310	0-3	101
22.4 Primary peritoneal serous/papillary carcinoma	C48	8050, 8260, 8441, 8450, 8460-8461	0-3	102
22.5 Mullerian mixed tumor of ovary and falloppian tube	C56.9, C57.0-C57.3	8950-8951, 8980-8981	0-3	103
22.6 Adenocarcinoma with variants of fallopian tube	C57.0-C57.3	8050, 8120, 8140-8141, 8143, 8147, 8190, 8200-8201, 8210-8211, 8221, 8230-8231, 8255, 8260-8263, 8290, 8310, 8315, 8320, 8323, 8333, 8380-8384, 8430, 8440-8441, 8460-8461, 8480-8482, 8490, 8504, 8510, 8512, 8514, 8525, 8542, 8550-8551, 8560, 8562, 8570-8576, 9014-9015, 9110	0-3	104
22.7 Other epithelial tumors of ovary and falloppian tube^*	C56.9	8000-8001, 8003-8005, 8010-8012, 8020-8022, 8030-8034, 8040, 8051-8052, 8070-8076, 8083-8084, 8340, 8410, 8474, 8560	0-3	105
23. Non Epithelial Tumors of Ovary
23.1 Sex cord tumor of ovary	C56	8590, 8600, 8620, 8630-8631, 8634, 8640, 8650, 8670	0-3	106
23.2 Malignant/Immature teratoma of ovary	C56	9080-9084, 9090-9091, 9102, 9391, 9440, 9473, 9501	0-3	107
23.3 Germ cell tumor of ovary	C56	9060-9065, 9070-9073, 9085, 9100-9101	0-3	108
23.4 Other non epithelial tumors of ovary^*	C57.1	9391	0-3	109
24. Epithelial Tumors of Vulva and Vagina
24.1 Squamous cell carcinoma with variants of vulva and vagina	C51, C52	8050-8052, 8070-8076, 8078, 8082-8084, 8090-8095, 8097, 8120, 8123	0-3	110
24.2 Adenocarcinoma with variants of vulva and vagina	C51, C52	8098, 8102, 8140-8141, 8143, 8147, 8190, 8200-8201, 8210-8211, 8230-8231, 8255, 8260-8263, 8290, 8310, 8315, 8320, 8323, 8333, 8380-8384, 8390, 8400-8403, 8407-8410, 8413, 8420, 8430, 8440, 8460, 8480-8482, 8490, 8500, 8503-8504, 8510, 8512, 8514, 8525, 8550-8551, 8562, 8570-8576, 8982, 9110	0-3	111
24.3 Pagets disease of vulva and vagina	C51, C52	8542-8543	0-3	112
24.4 Undifferentiated carcinoma of vulva and vagina	C51, C52	8020-8022	0-3	113
24.5 Mullerian mixed tumor of vulva and vagina	C51, C52	8950-8951, 8980	0-3	114
24.6 Other epithelial tumors of vulva and vagina^*	C51, C52	8000-8001, 8003-8004, 8010-8012, 8030, 8032-8033, 8144, 8560	0-3	115
25. Trophoblastic Tumors of Placenta
25.1 Choriocarcinoma of placenta	C58.9	9100	0-3	116
25.2 Other trophoblastic tumors of placenta^*	C58.9	8000-8001, 9101-9102, 9104-9105	0-3	117
26. Epithelial Tumors of Prostate
26.1 Adenocarcinoma with variants of prostate	C61	8030, 8032-8033, 8074, 8082, 8140-8141, 8143, 8145, 8190, 8210-8211, 8231, 8251, 8255, 8261-8263, 8290, 8310, 8320, 8323, 8333, 8380-8384, 8430, 8440-8441, 8450, 8480-8482, 8490, 8504, 8510, 8512, 8514, 8525, 8542, 8550-8551, 8562, 8570-8576, 8941, 8980	0-3	118
26.2 Squamous cell carcinoma with variants of prostate	C61	8051-8052, 8070-8073, 8075-8076, 8084, 8121, 8123, 8560	0-3	119
26.3 Infiltrating duct carcinoma of prostate	C61	8050, 8201, 8230, 8260, 8500, 8503	0-3	120
26.4 Transitional cell carcinoma of prostate	C61	8120, 8122, 8130-8131	0-3	121
26.5 Basal cell adenocarcinoma of prostate	C61	8147, 8200	0-3	122
26.6 Other epithelial tumors of prostate^*	C61	8000-8001, 8003-8005, 8010-8012, 8014-8015, 8020-8022, 8031, 8034, 8040, 8951	0-3	123
27. Testicular and Paratesticular Cancers
27.1 Paratesticular adenocarcinoma with variants	C63.0, C63.1, C63.8	8120, 8123, 8140-8141, 8147, 8190, 8200, 8210-8211, 8221, 8230-8231, 8255, 8260-8263, 8290, 8310, 8320, 8323, 8333, 8380-8384, 8401, 8430, 8440-8441, 8460, 8470, 8480-8482, 8490, 8504, 8510, 8512, 8514, 8525, 8542, 8550-8551, 8560, 8562, 8570-8576	0-3	124
27.2 Non seminomatous testicular cancer	C62	9065, 9070-9072, 9080-9083, 9085, 9100-9102, 9105	0-3	125
27.3 Seminomatous testicular cancer	C62	9060-9062	0-3	126
27.4 Spermatocytic seminoma	C62	9063	0-3	127
27.5 Teratoma with malignant transformation	C62	9084	0-3	128
27.6 Testicular sex cord cancer	C62	8630-8631, 8634, 8640, 8650	0-3	129
27.7 Other testicular and paratesticular cancers^*	C62	8000-8001, 9064	0-3	130
28. Epithelial Tumors of Penis
28.1 Squamous cell carcinoma with variants of penis	C60	8020-8022, 8050-8052, 8054, 8070-8076, 8078, 8082-8084, 8090, 8094, 8123, 8320, 8560, 8980	0-3	131
28.2 Adenocarcinoma with variants of penis	C60	8140-8141, 8147, 8190, 8200-8201, 8210-8211, 8221, 8230-8231, 8255, 8260-8263, 8310, 8323, 8402, 8410, 8440, 8480-8482, 8490, 8504, 8510, 8512, 8514, 8525, 8542, 8550-8551, 8562, 8570-8576, 8940, 8982	0-3	132
28.3 Other epithelial tumors of penis^*	C60	8000-8001, 8003-8004, 8010-8012, 8031-8033, 8095, 8120, 8390, 8430	0-3	133
29. Epithelial Tumors of Kidney
29.1 Renal cell carcinoma with variants	C64	8005, 8050, 8140-8141, 8143, 8147, 8190, 8200-8201, 8211, 8221, 8230-8231, 8251, 8255, 8260-8263, 8270, 8290, 8300, 8310-8312, 8315-8320, 8323, 8330, 8333, 8401, 8430, 8440, 8450, 8480-8482, 8490, 8500, 8503-8504, 8510, 8512, 8514, 8525, 8542, 8550-8551, 8562, 9110	0-3	134
29.2 Squamous cell carcinoma spindle cell type of kidney	C64	8004, 8032, 8074, 8980	0-3	135
29.3 Squamous cell carcinoma with variants of kidney	C64	8020-8022, 8051-8052, 8070-8073, 8075-8076, 8078, 8082-8084, 8560	0-3	136
29.4 Other epithelial tumors of the kidney^*	C64	8000-8001, 8003, 8010-8012, 8014, 8030-8031, 8033-8035, 8123, 8210, 8280, 8380-8384, 8570-8576, 8981	0-3	137
30. Epithelial Tumors of Pelvis and Ureter
30.1 Transitional cell carcinoma of pelvis and ureter	C65.9,C66.9	8020-8022, 8031, 8082, 8120-8122, 8130-8131	0-3	138
30.2 Squamous cell carcinoma with variants of pelvis and ureter	C65.9,C66.9	8004, 8050-8052, 8070-8076, 8123	0-3	139
30.3 Adenocarcinoma with variants of pelvis and ureter	C65.9,C66.9	8005, 8140-8141, 8143, 8147, 8190, 8200-8201, 8211, 8221, 8230-8231, 8251, 8255, 8260-8263, 8270, 8280, 8290, 8300, 8310, 8320, 8323, 8330, 8342, 8430, 8480-8482, 8490, 8500, 8510, 8512, 8514, 8525, 8542, 8560, 8570, 9110	0-3	140
30.4 Other epithelial tumors of pelvis and ureter^*	C65.9,C66.9	8000-8001, 8003, 8010-8012, 8014, 8030, 8032-8033, 8035, 8078, 8083-8084, 8145, 8210, 8440, 8504, 8550, 8562, 8571-8576, 8980	0-3	141
31. Epithelial Tumors of Urethra
31.1 Transitional cell carcinoma of urethra	C68.0, C68.1	8020-8022, 8031, 8082, 8120-8122, 8130-8131	0-3	142
31.2 Squamous cell carcinoma with variants of urethra	C68.0, C68.1	8050-8052, 8070-8076, 8094, 8123	0-3	143
31.3 Adenocarcinoma with variants of urethra	C68.0, C68.1	8140-8141, 8143, 8147, 8190, 8200-8201, 8210-8211, 8221, 8230-8231, 8255, 8260-8263, 8290, 8310, 8320, 8323, 8430, 8480-8482, 8490, 8510, 8512, 8514, 8525, 8542, 8550-8551, 8560, 8570, 9110	0-3	144
31.4 Other epithelial tumors of urethra^*	C68.0, C68.1	8000-8001, 8004, 8010-8012, 8033, 8078, 8083-8084, 8380, 8440, 8504, 8562, 8571-8576, 8980	0-3	145
32. Epithelial Tumors of Bladder
32.1 Transitional cell carcinoma of bladder	C67	8020-8022, 8030-8033, 8082, 8120-8122, 8130-8131, 8145	0-3	146
32.2 Squamous cell carcinoma with variants of bladder	C67	8050-8052, 8070-8076, 8078, 8083-8084, 8094, 8123	0-3	147
32.3 Adenocarcinoma with variants of bladder	C67	8140-8141, 8143-8144, 8147, 8190, 8201, 8210-8211, 8221, 8230-8231, 8255, 8260-8263, 8290, 8310, 8320, 8323, 8380, 8440, 8460, 8480-8482, 8490, 8510, 8512, 8514, 8525, 8542, 8560, 8570, 9110	0-3	148
32.4 Salivary gland type tumor of bladder	C67	8200, 8430	0-3	149
32.5 Other epithelial tumors of bladder^*	C67	8000-8001, 8003-8004, 8010-8012, 8015,8034-8035, 8550-8551, 8562, 8571-8575, 8951, 8980	0-3	150
33. Epithelial Tumors of Eye and Adnexa
33.1 Squamous cell carcinoma with variants of eye and adnexa	C69.0-C69.9	8020, 8050-8052, 8070-8076, 8078, 8082-8084, 8090	0-3	151
33.2 Adenocarcinoma with variants of eye and adnexa	C69.0-C69.9	8140, 8147, 8190, 8200, 8211, 8221, 8230-8231, 8255, 8260-8263, 8290, 8310, 8320, 8323, 8410, 8430, 8440, 8480-8482, 8490, 8510, 8512, 8514, 8525, 8542, 8550-8551, 8560, 8562, 8570-8576, 8941	0-3	152
33.3 Other epithelial tumors of eye and adnexa^*	C69.0-C69.9	8000-8001, 8004, 8010-8011, 8032, 8094, 8097, 8120-8121, 8123, 8141	0-3	153
34. Epithelial Tumors of Middle Ear
34.1 Squamous cell carcinoma with variants middle ear	C30.1	8050-8052, 8070-8076, 8078, 8082-8084, 8090, 8094, 8120-8121, 8123, 8130	0-3	154
34.2 Adenocarcinoma with variants of middle ear	C30.1	8140, 8147, 8190, 8200, 8211, 8221, 8230-8231, 8255, 8260-8263, 8290, 8310, 8320, 8323, 8410, 8430, 8440, 8480-8482, 8490, 8510, 8512, 8514, 8525, 8542, 8550-8551, 8560, 8562, 8570-8576	0-3	155
34.3 Other Adenocarcinoma with variants of middle ear^*	C30.1	8000-8001, 8003-8004, 8010-8012, 8020, 8022, 8032, 8141, 8201, 8401	0-3	156
35. Malignant Mesothelioma
35.1 Mesothelioma of pleura and pericardium	C38	9050, 9051, 9052, 9053	0-3	157
35.2 Mesothelioma of peritoneum and tunica vaginalis	C48, C63.7	9050, 9051, 9052, 9053	0-3	158
35.3 Other malignant mesothelioma^*	C00-C37, C39-C47, C49-C63.6, C63.8-C80	9050, 9051, 9052, 9053	0-3	159
36. Malignant Skin Melanoma
36.1 Superficial spreading melanoma	C44, C63.2, C51, C60	8743	0-3	160
36.2 Nodular melanoma	C44, C63.2, C51, C60	8721	0-3	161
36.3 Lentigo maligna melanoma	C44, C63.2, C51, C60	8742	0-3	162
36.4 Acral lentiginous melanoma malignant	C44, C63.2, C51, C60	8744	0-3	163
36.5 Other malignant skin melanoma^*	C44, C63.2, C51, C60	8720, 8722-8723, 8728, 8730, 8740-8741, 8745-8746, 8761, 8770-8774, 8780	0-3	164
37. Malignant Melanoma of Mucosa and Extracutaneous	C00-C26, C30-C34, C52-C57, C61-C62, C64-C68, C70-C75	8720-8723, 8728, 8730, 8740-8746, 8761, 8770-8774, 8780	0-3	165
38. Malignant Melanoma of Eye
38.1 Malignant melanoma of conjunctiva	C69.0	8720-8723, 8728, 8730, 8740-8746, 8761, 8770-8774, 8780	0-3	166
38.2 Malignant melanoma of uvea	C69.3-C69.4	8720-8723, 8728, 8730, 8740-8746, 8761, 8770-8774, 8780	0-3	167
38.3 Other malignant melanoma of eye^*	C69.1-C69.2, C69.5-C69.9	8720-8723, 8728, 8730, 8740-8746, 8761, 8770-8774, 8780	0-3	168
39. Epithelial Tumors of Skin
39.1 Basal cell carcinoma of skin	C44, C63.2	8090-8095, 8097-8098	0-3	169
39.2 Squamous cell carcinoma with variants of skin	C44, C63.2	8011, 8032, 8050-8052, 8070-8076, 8078, 8560	0-3	170
39.3 Other epithelial tumors of skin^*	C44, C63.2	8980	0-3	171
40. Adnexal Carcinomas of Skin
40.1 Nodular hidradenoma, malignant	C44, C63.2	8402	0-3	172
40.2 Sebaceous adenocarcinoma	C44, C63.2	8410	0-3	173
40.3 Adenoid cystic carcinoma	C44, C63.2	8200	0-3	174
40.4 Pagets disease extramammary	C44, C63.2	8542	0-3	175
40.5 Apocrine adenocarcinoma	C44, C63.2	8401	0-3	176
40.6 Mucinous adenocarcinoma	C44, C63.2	8480-8481	0-3	177
40.7 Pilomatrix carcinoma	C44, C63.2	8110	0-3	178
40.8 Eccrine poroma, malignant	C44, C63.2	8409	0-3	179
40.9 Mixed tumor malignant, NOS	C44, C63.2	8940	0-3	180
40.10 Sclerosing sweat duct carcinoma	C44, C63.2	8407	0-3	181
40.11 Malignant eccrine spiradenoma	C44, C63.2	8403	0-3	182
40.12 Tubular adenocarcinoma	C44, C63.2	8211	0-3	183
40.13 Eccrine papillary adenocarcinoma	C44, C63.2	8408	0-3	184
40.14 Other adnexal carcinomas of skin^*	C44, C63.2	8100, 8102, 8123, 8140-8141, 8143, 8147, 8190, 8201, 8230-8231, 8255, 8260, 8310, 8320, 8323, 8330, 8390, 8400, 8413, 8420, 8430, 8440-8441, 8450, 8470, 8490, 8500, 8504, 8510, 8514, 8520-8521, 8523, 8550, 8562, 8570-8571, 8574-8575, 8941, 8982	0-3	185
41. Neuroblastoma and Ganglioneuroblastoma	C00-C69, C73-C80	9490, 9500	0-3	186
42. Nephroblastoma	C64.9	8960	0-3	187
43. Embryonal Tumors of Eye
43.1 Retinoblastoma	C69.2, C69.9	9510-9514	0-3	188
43.2 Medulloepithelioma	C69.4	9501-9502	0-3	189
44. Hepatoblastoma	C22.0	8970	0-3	190
45. Pleuropulmonary Blastoma	C34, C38.4	8973	0-3	191
46. Pancreatoblastoma	C25	8971	0-3	192
47. Olfactory Neuroblastoma	C00-C80	9520-9523	0-3	193
48. Odontogenic Malignant Tumors
48.1 Odontogenic tumor, malignant	C00-C80	9270	0-3	194
48.2 Clear cell odontogenic carcinoma	C00-C80	9341	0-3	195
48.3 Ghost cell odontogenic carcinoma	C00-C80	9302	0-3	196
48.4 Other odontogenic malignant tumors^*	C00-C80	9261, 9290, 9310, 9330, 9342	0-3	197
49. Extragonadal Germ Cell Tumors
49.1 Non seminomatous germ cell tumor	C00-C55, C57, C59-C61, C63-C70, C73-C75.0, C75.2, C75.4-C80	9065, 9070-9071, 9080-9085, 9100-9102, 9105	0-3	198
49.2 Seminomatous germ cell tumor	C00-C55, C57, C59-C61, C63-C70, C73-C75.0, C75.2, C75.4-C80	9060-9063	0-3	199
49.3 Germ cell tumor of Central Nervous System (CNS)	C71-C72, C75.1, C75.3	9060-9065, 9070-9071, 9080-9085, 9100-9102, 9105	0-3	200
49.4 Other extragonadal germ cell tumors^*	C00-C55, C57, C59-C61, C63-C70, C73-C75.0, C75.2, C75.4-C80	9064	0-3	201
50. Soft Tissue Sarcoma	C00-C29, C30.2-C32.2, C32.4-C33.8, C34.1-C39, C42-C80	8710-8711, 8714, 8800-8806, 8810-8815, 8825, 8830, 8832-8833, 8840, 8842, 8850-8855, 8857-8858, 8890-8891, 8894-8896, 8900-8902, 8910, 8912, 8920-8921, 8930-8931, 8933-8935, 8959, 8963-8964, 8990-8991, 9020, 9040-9044, 9120, 9124, 9130, 9133, 9137, 9150, 9170, 9180-9183, 9185-9187, 9192-9195, 9220, 9231, 9240, 9251-9252, 9260, 9364-9365, 9540, 9542, 9560-9561, 9571, 9580-9581	0-3	202-220
	C00-C06, C09-C29.9, C30.2-C32.2, C32.4-C33.8, C34.1-C39, C42-C43, C45-C59, C61-C63.1, C63.3-C80	8940
	C49	8004
	C00-C29, C30.2-C32.2, C32.4-C33.8, C34.1-C39, C42-C55, C57-C70, C73-C80	9473
	C00-C29, C30.2-C32.2, C32.4-C33.8, C34.1-C39, C42-C70, C73-C80	9503
50.1 Soft tissue sarcoma of head and neck	C00.0-C14.8, C31.0-C32.2, C32.4-32.9, C49.0, C73.9, C75.2, C75.4, C76.0	8710-8711, 8714, 8800-8806, 8810-8815, 8825, 8830, 8832-8833, 8840, 8842, 8850-8855, 8857-8858, 8890-8891, 8894-8896, 8900-8902, 8912, 8921, 8933-8935, 8963, 8990-8991, 9040-9044, 9120, 9124, 9130, 9133, 9137, 9150, 9170, 9180-9183, 9185-9187, 9192-9195, 9220, 9231, 9240, 9252, 9365, 9540, 9542, 9560-9561, 9571, 9580-9581	0-3	202
50.2 Soft tissue sarcoma of limbs	C49.1-C49.2, C76.4-C76.5	8710-8711, 8714, 8800-8806, 8810-8815, 8825, 8830, 8832-8833, 8840, 8842, 8850-8855, 8857-8858, 8890-8891, 8894-8896, 8900-8902, 8912, 8921, 8933-8935, 8940, 8963, 8990-8991, 9040-9044, 9120, 9124, 9130, 9133, 9137, 9150, 9170, 9180-9183, 9185-9187, 9192-9195, 9220, 9231, 9240, 9252, 9365, 9540, 9542, 9560-9561, 9571, 9580-9581	0-3	203
50.3 Soft tissue sarcoma of superficial trunk	C49.3-C49.4, C49.6, C76.1-C76.2, C76.7	8710-8711, 8714, 8800-8806, 8810-8815, 8825, 8830, 8832-8833, 8840, 8842, 8850-8855, 8857-8858, 8890-8891, 8894-8896, 8900-8902, 8912, 8921, 8933-8935, 8940, 8963, 8990-8991, 9040-9044, 9120, 9124, 9130, 9133, 9137, 9150, 9170, 9180-9183, 9185-9187, 9192-9195, 9220, 9231, 9240, 9252, 9365, 9540, 9542, 9560-9561, 9571, 9580-9581	0-3	204
50.4 Soft tissue sarcoma of mediastinum	C38.1-C38.3, C38.8	8710-8711, 8714, 8800-8806, 8810-8815, 8825, 8830, 8832-8833, 8840, 8842, 8850-8855, 8857-8858, 8890-8891, 8894-8896, 8900-8902, 8912, 8921, 8933-8935, 8940, 8963, 8990-8991, 9040-9044, 9120, 9124, 9130, 9133, 9137, 9150, 9170, 9180-9183, 9185-9187, 9192-9195, 9220, 9231, 9240, 9252, 9365, 9540, 9542, 9560-9561, 9571, 9580-9581	0-3	205
50.5 Soft tissue sarcoma of heart	C38.0	8710-8711, 8714, 8800-8806, 8810-8815, 8825, 8830, 8832-8833, 8840, 8842, 8850-8855, 8857-8858, 8890-8891, 8894-8896, 8900-8902, 8912, 8921, 8933-8935, 8940, 8963, 8990-8991, 9040-9044, 9120, 9124, 9130, 9133, 9137, 9150, 9170, 9180-9183, 9185-9187, 9192-9195, 9220, 9231, 9240, 9252, 9365, 9540, 9542, 9560-9561, 9571, 9580-9581	0-3	206
50.6 Soft tissue sarcoma of breast	C50	8710-8711, 8714, 8800-8806, 8810-8815, 8825, 8830, 8832-8833, 8840, 8842, 8850-8855, 8857-8858, 8890-8891, 8894-8896, 8900-8902, 8912, 8921, 8933-8935, 8940, 8963, 8990-8991, 9020, 9040-9044, 9120, 9124, 9130, 9133, 9137, 9150, 9170, 9180, 9231, 9240, 9252, 9365, 9540, 9542, 9560-9561, 9571, 9580-9581	0-3	207
50.7 Soft tissue sarcoma of uterus	C53-C55	8710-8711, 8714, 8800-8806, 8810-8815, 8825, 8830, 8832-8833, 8840, 8842, 8850-8855, 8857-8858, 8890-8891, 8894-8896, 8900-8902, 8912, 8921, 8930-8931, 8933-8935, 8940, 8963, 8990-8991, 9040-9044, 9120, 9124, 9130, 9133, 9137, 9150, 9170, 9180-9183, 9185-9187, 9192-9195, 9220, 9231, 9240, 9252, 9365, 9540, 9542, 9560-9561, 9571, 9580-9581	0-3	208
50.8 Soft tissue sarcoma of paratestis	C63.0-C63.7	8710-8711, 8714, 8800-8806, 8810-8815, 8825, 8830, 8832-8833, 8840, 8842, 8850-8855, 8857-8858, 8890-8891, 8894-8896, 8900-8902, 8912, 8921, 8933-8935, 8963, 8990-8991, 9040-9044, 9120, 9124, 9130, 9133, 9137, 9150, 9170, 9180-9183, 9185-9187, 9192-9195, 9220, 9231, 9240, 9252, 9365, 9540, 9542, 9560-9561, 9571, 9580-9581	0-3	209
50.8 Soft tissue sarcoma of paratestis	C63.0-C63.1, C63.3-C63.7	8940	0-3	209
50.9 Soft tissue sarcomas of other genitourinary tract	C51.0-C52.9, C56.9-C57.9, C60.0-C62.9, C63.8-C63.9, C64.9-C68.9	8710-8711, 8714, 8800-8806, 8810-8815, 8830, 8832-8833, 8840, 8842, 8850-8855, 8857-8858, 8890-8891, 8894-8896, 8900-8902, 8912, 8921, 8933-8935, 8959, 8963-8964, 8990-8991, 9040-9044, 9120, 9124, 9130, 9133, 9137, 9150, 9170, 9180-9183, 9185-9187, 9192-9195, 9220, 9231, 9240, 9252, 9365, 9540, 9542, 9560-9561, 9571, 9580-9581	0-3	210
50.9 Soft tissue sarcomas of other genitourinary tract	C51.0-C52.9, C56.9-C57.9, C61.9-C62.9, C63.8-C63.9, C64.9-C68.9	8940	0-3	210
50.10 Soft tissue sarcoma of viscera	C15-C26, C34.1-C37, C38.4, C39, C42.2	8710-8711, 8714, 8800-8806, 8810-8815, 8825, 8830, 8832-8833, 8840, 8842, 8850-8855, 8857-8858, 8890-8891, 8894-8896, 8900-8902, 8912, 8921, 8933-8935, 8940, 8963, 8990-8991, 9040-9044, 9120, 9124, 9130, 9133, 9137, 9150, 9170, 9180-9183, 9185-9187, 9192-9195, 9220, 9231, 9240, 9252, 9365, 9540, 9542, 9560-9561, 9571, 9580-9581	0-3	211
50.11 Soft tissue sarcoma of retroperitoneum and peritoneum	C48.0-C48.8	8710-8711, 8714, 8800-8806, 8810-8815, 8825, 8830, 8832-8833, 8840, 8842, 8850-8855, 8857-8858, 8890-8891, 8894-8896, 8900-8902, 8912, 8921, 8933-8935, 8940, 8963, 8990-8991, 9040-9044, 9120, 9124, 9130, 9133, 9137, 9150, 9170, 9180-9183, 9185-9187, 9192-9195, 9220, 9231, 9240, 9252, 9365, 9540, 9542, 9560-9561, 9571, 9580-9581	0-3	212
50.12 Soft tissue sarcoma of pelvis	C49.5, C76.3	8710-8711, 8714, 8800-8806, 8810-8815, 8825, 8830, 8832-8833, 8840, 8842, 8850-8855, 8857-8858, 8890-8891, 8894-8896, 8900-8902, 8912, 8921, 8933-8935, 8940, 8963, 8990-8991, 9040-9044, 9120, 9124, 9130, 9133, 9137, 9150, 9170, 9180-9183, 9185-9187, 9192-9195, 9220, 9231, 9240, 9252, 9365, 9540, 9542, 9560-9561, 9571, 9580-9581	0-3	213
50.13 Soft tissue sarcoma of skin	C44	8710-8711, 8714, 8800-8806, 8810-8815, 8825, 8830, 8832-8833, 8840, 8842, 8850-8855, 8857-8858, 8890-8891, 8894-8896, 8900-8902, 8912, 8921, 8933-8935, 8963, 8990-8991, 9040-9044, 9120, 9124, 9130, 9133, 9137, 9150, 9170, 9180-9183, 9185-9187, 9192-9195, 9220, 9231, 9240, 9252, 9365, 9540, 9542, 9560-9561, 9571, 9580-9581	0-3	214
50.14 Soft tissue sarcoma of paraorbit	C69	8710-8711, 8714, 8800-8806, 8810-8815, 8825, 8830, 8832-8833, 8840, 8842, 8850-8855, 8857-8858, 8890-8891, 8894-8896, 8900-8902, 8912, 8921, 8933-8935, 8940, 8963, 8990-8991, 9040-9044, 9120, 9124, 9130, 9133, 9137, 9150, 9170, 9180-9183, 9185-9187, 9192-9195, 9220, 9231, 9240, 9252, 9365, 9540, 9542, 9560-9561, 9571, 9580-9581	0-3	215
50.15 Soft tissue sarcoma of brain and other parts of the nervous system	C47, C70-C72, C75.1, C75.3	8710-8711, 8714, 8800-8806, 8810-8815, 8825, 8830, 8832-8833, 8840, 8842, 8850-8855, 8857-8858, 8890-8891, 8894-8896, 8900-8902, 8912, 8921, 8933-8935, 8940, 8963, 8990-8991, 9040-9044, 9120, 9124, 9130, 9133, 9137, 9150, 9170, 9180-9183, 9185-9187, 9192-9195, 9220, 9231, 9240, 9252, 9365, 9540, 9542, 9560-9561, 9571, 9580-9581	0-3	216
50.16 Embryonal rhabdomyosarcoma of soft tissue	C00-C29, C30.2-C32.2, C32.4-C33.8, C34.1-C39, C42-C80	8910	0-3	217
50.17 Alveolar rhabdomyosarcoma of soft tissue	C00-C29, C30.2-C32.2, C32.4-C33.8, C34.1-C39, C42-C80	8920	0-3	218
50.18 Ewings sarcoma of soft tissue	C00-C29, C30.2-C32.2, C32.4-C33.8, C34.1-C39, C42-C80	9260, 9364	0-3	219
50.18 Ewings sarcoma of soft tissue	C00-C29, C30.2-C32.2, C32.4-C33.8, C34.1-C39, C42-C55, C57-C70, C73-C80	9473	0-3	219
50.19 Other soft tissue sarcoma^*	C14.9, C27-C29, C30.2-C30.9, C33.0-C33.8, C38.5-C38.7, C38.9, C42.0-C42.1, C42.3-C43, C45-C46, C48.9, C49.7-C49.9, C56.0-C56.8, C58-C59, C64.0-C64.8, C73.0-C73.8, C74-C75.0, C75.5-C75.9, C76.6, C76.8-C80	8710-8711, 8714, 8800-8806, 8810-8815, 8825, 8830, 8832-8833, 8840, 8842, 8850-8855, 8857-8858, 8890-8891, 8894-8896, 8900-8902, 8912, 8921, 8930-8931, 8933-8935, 8959, 8963-8964, 8990-8991, 9020, 9040-9044, 9120, 9124, 9130, 9133, 9137, 9150, 9170, 9180-9183, 9185-9187, 9192-9195, 9220, 9231, 9240, 9251-9252, 9365, 9540, 9542, 9560-9561, 9571, 9580-9581	0-3	220
	C00.0-C14.8, C31.0-C32.2, C32.4-32.9, C49.0-C49.2, C73.9, C75.2, C75.4, C76.0, C76.4-C76.5	8930-8931, 8959, 8964, 9020, 9251
	C38.1-C38.3, C38.8, C47.0-C47.9, C49.3-C49.4, C49.6, C70.0-C72.9, C75.1, C75.3, C76.1-C76.2, C76.7	8930-8931, 8959, 8964, 9020, 9251
	C15.0-C26.9, C34.1-C38.0, C38.4, C39.0-C39.9, C42.2, C48.0-C48.8, C49.5, C63.0-C63.7, C69.0-C69.9, C76.3	8930-8931, 8959, 8964, 9020, 9251
	C50	8930-8931, 8959, 8964, 9181-9183, 9185-9187, 9192-9195, 9220, 9251
	C53-C55	8959, 8964, 9020, 9251
	C51-C52, C56.9-C57, C60-C62, C63.8-C63.9, C64.9-C68	8825, 8930-8931, 9020, 9251
	C44	8930-8931, 8959, 8964, 9020, 9251
	C00-C06, C09-C14.9, C27-C29.9, C30.2-C32.2, C32.4-C33.8, C38.5-C38.7, C38.9, C42.0-C42.1, C42.3-C43, C45-C46, C48.9-C49.0, C49.7-C49.9, C56.0-C56.8, C58-C59, C61.0-C61.8, C64.0-C64.8, C73-C75.0, C75.2, C75.4-C76.0, C76.6, C76.8-C80	8940
	C49	8004
	C00-C29, C30.2-C32.2, C32.4-C33.8, C34.1-C39, C42-C70, C73-C80	9503
51. Bone Sarcoma	C30.0-C30.1, C32.3, C33.9-C34.0, C40-C41	8800-8806, 8810-8812, 8815, 8830, 8840, 8850-8855, 8890-8891, 8894-8896, 8900-8902, 8910, 8912, 8920, 9040-9044, 9120, 9124, 9130, 9133, 9150, 9170, 9180-9187, 9192-9195, 9220-9221, 9230-9231, 9240, 9242-9243, 9250, 9260, 9364, 9473, 9540, 9560-9561, 9571, 9580-9581	0-3	221-227
	C40-C41	8004
	C00-C80	9370-9372
51.1 Osteogenic sarcoma	C30.0-C30.1, C32.3, C33.9-C34.0, C40-C41	9180-9183, 9185-9187, 9192-9195	0-3	221
51.2 Chondrogenic sarcoma	C30.0-C30.1, C32.3, C33.9-C34.0, C40-C41	9220-9221, 9230-9231, 9240, 9242-9243	0-3	222
51.3 Notochordal sarcoma, chordoma	C00-C80	9370-9372	0-3	223
51.4 Vascular sarcoma	C30.0-C30.1, C32.3, C33.9-C34.0, C40-C41	9120, 9124, 9130, 9133, 9150, 9170	0-3	224
51.5 Ewings sarcoma	C30.0-C30.1, C32.3, C33.9-C34.0, C40-C41	9260, 9364, 9473	0-3	225
51.6 Other high grade sarcomas (fibrosarcoma, malignant fibrous histiocytoma)	C30.0-C30.1, C32.3, C33.9-C34.0, C40-C41	8810, 8830	0-3	226
51.7 Other bone sarcoma^*	C30.0-C30.1, C32.3, C33.9-C34.0, C40-C41	8800-8806, 8811-8812, 8815, 8840, 8850-8855, 8890-8891, 8894-8896, 8900-8902, 8910, 8912, 8920, 9040-9044, 9184, 9250, 9540, 9560-9561, 9571, 9580-9581	0-3	227
51.7 Other bone sarcoma^*	C40-C41	8004	0-3	227
52. Gastrointestinal Stromal Sarcoma	All cancer sites	8936	0-3	228
53. Kaposis Sarcoma	All cancer sites	9140	0-3	229
54. NET GEP
54.1 Well diff not functioning endocrine carc of pancreas and digestive tract	C15-26, C48	8150, 8240-8245, 8248-8249	0-3	230
54.2 Well diff functioning endocrine carc of pancreas and digestive tract	C15-26, C48	8151-8153, 8155-8157	0-3	231
54.3 Poorly differentiated endocrine carcinoma of pancreas and digestive tract	C15-26, C48	8002, 8013, 8041-8045, 8246	0-3	232
54.4 Malignant mixed pancreatic endocrine and exocrine tumor	C15-26	8154	0-3	233
54.5 Other NET GEP^*	C48	8154	0-3	234
55. NET Lung/typical and Atypical Carcinoid of the Lung	C34	8240, 8241, 8242, 8243, 8244, 8245, 8249	0-3	235
56. NET Other Sites	C74	8700	0-3	236-240
	C00-C80	8247, 8680, 8693
	C73.9	8002, 8013, 8041, 8240, 8244-8246, 8249, 8345-8347, 8510, 8512
	C44.0-C44.9, C51.0-C51.9, C60.0, C60.9, C63.2	8002, 8013, 8041, 8240, 8244-8246, 8249
	C00-C14, C27-C33, C35-C43, C45-C47, C49-C50, C52-C59, C61-C63.1, C63.3-C73.8, C74-C80	8002, 8013, 8041-8045, 8150-8153, 8155-8157, 8240-8246, 8248-8249
56.1 Pheochromocytoma, malignant	C74	8700	0-3	236
56.2 Paraganglioma	C00-C80	8680, 8693	0-3	237
56.3 Endocrine carcinoma of thyroid gland	C73.9	8002, 8013, 8041, 8240, 8244-8246, 8249, 8345-8347, 8510, 8512	0-3	238
56.4 Neuroendocrine carcinoma of skin	C44.0-C44.9, C51.0-C51.9, C60.0, C60.9, C63.21	8002, 8013, 8041, 8240, 8244-8246, 8249	0-3	239
56.4 Neuroendocrine carcinoma of skin	C00-C80	8247	0-3	239
56.5 Neuroendocrine carcinoma of other sites	C00-C14, C27-C33, C35-C43, C45-C47, C49-C50, C52-C59, C61-C63.1, C63.3-C73.8, C74-C80	8002, 8013, 8041-8045, 8150-8153, 8155-8157, 8240-8246, 8248-8249	0-3	240
57. Carcinomas of Pituitary Gland	C75.1	8000-8001, 8010, 8012, 8020-8021, 8140-8145, 8180, 8190, 8200-8201, 8210-8211, 8214-8215, 8220-8221, 8230-8231, 8250-8255, 8260-8263, 8270, 8272, 8280-8281, 8290, 8300, 8310, 8312-8320, 8322-8323, 8330-8333, 8335, 8337, 8341-8347, 8350, 8370, 8380-8381	0-3	241-242
57.1 Pituitary carcinoma	C75.1	8272	0-3	241
57.2 Other carcinomas of pituitary gland^*	C75.1	8000-8001, 8010, 8012, 8020-8021, 8140-8145, 8180, 8190, 8200-8201, 8210-8211, 8214-8215, 8220-8221, 8230-8231, 8250-8255, 8260-8263, 8270, 8280-8281, 8290, 8300, 8310, 8312-8320, 8322-8323, 8330-8333, 8335, 8337, 8341-8347, 8350, 8370, 8380-8381	0-3	242
58. Carcinomas of Thyroid Gland	C73.9	8000-8001, 8003-8005, 8010-8012, 8014-8015, 8020-8022, 8030-8035, 8050-8052, 8070-8076, 8078, 8082-8084, 8140-8141, 8190, 8200-8201, 8211, 8230, 8255, 8260-8263, 8290, 8310, 8320, 8322-8323, 8330-8335, 8337, 8339-8344, 8350, 8360, 8380, 8430, 8440, 8450, 8480-8481, 8490, 8500, 8504, 8514, 8520, 8550, 8560, 8562, 8574, 8580, 8588-8589, 8941, 8980, 8982	0-3	243-250
58.1 Papillary adenocarcinoma, NOS	C73.9	8050, 8260	0-3	243
58.2 Follicular carcinoma, NOS	C73.9	8330, 8339	0-3	244
58.3 Undifferentiated/anaplastic carcinoma	C73.9	8020-8022, 8030-8033	0-3	245
58.4 Mucoepidermoid carcinoma	C73.9	8430	0-3	246
58.5 Mucinous carcinoma	C73.9	8480-8481	0-3	247
58.6 Spindle cell tumor with thymus-like differentiation (SETTLE)	C73.9	8588	0-3	248
58.7 Carcinoma showing thymus-like differentiation (CASTLE)	C73.9	8589	0-3	249
58.8 Other carcinomas of thyroid gland^*	C73.9	8000-8001, 8003-8005, 8010-8012, 8014-8015, 8034-8035, 8051-8052, 8070-8076, 8078, 8082-8084, 8140-8141, 8190, 8200-8201, 8211, 8230, 8255, 8261-8263, 8290, 8310, 8320, 8322-8323, 8331-8335, 8337, 8340-8344, 8350, 8360, 8380, 8440, 8450, 8490, 8500, 8504, 8514, 8520, 8550, 8560, 8562, 8574, 8580, 8941, 8980, 8982	0-3	250
59. Carcinomas of Parathyroid Gland	C75.0	8000, 8001, 8010, 8011, 8012, 8014, 8015, 8020, 8021, 8022, 8030, 8031, 8032, 8033, 8034, 8035, 8050, 8051, 8052, 8070, 8071, 8072,8073, 8074, 8075, 8076, 8140, 8147, 8190, 8200, 8211, 8230, 8231, 8255, 8260, 8261, 8262, 8263, 8290, 8310, 8320, 8322, 8323, 8340, 8430, 8440, 8480, 8481, 8490, 8504, 8510, 8512, 8514, 8525, 8542, 8550, 8551, 8560, 8562,8570, 8571, 8572, 8573, 8575, 8576, 8980	0-3	251
60. Carcinomas of Adrenal Cortex	C74	8000-8001, 8003-8005, 8010-8012, 8014-8015, 8020-8022, 8030-8035, 8050-8052, 8070-8076, 8140, 8147, 8190, 8211, 8230-8231, 8255, 8260-8263, 8290, 8310, 8315, 8320, 8323, 8370, 8430, 8440, 8480-8481, 8490, 8504, 8510, 8512, 8514, 8525, 8542, 8550-8551, 8560, 8562, 8570-8573, 8575-8576, 8671, 8980	0-3	252-253
60.1 Adrenal cortical carcinoma	C74	8370	0-3	252
60.2 Other carcinomas of adrenal cortex^*	C74	8000-8001, 8003-8005, 8010-8012, 8014-8015, 8020-8022, 8030-8035, 8050-8052, 8070-8076, 8140, 8147, 8190, 8211, 8230-8231, 8255, 8260-8263, 8290, 8310, 8315, 8320, 8323, 8430, 8440, 8480-8481, 8490, 8504, 8510, 8512, 8514, 8525, 8542, 8550-8551, 8560, 8562, 8570-8573, 8575-8576, 8671, 8980	0-3	253
61. Tumors of Central Nervous System (CNS)	C71-C72	8000-8001, 9380-9382, 9385, 9391-9393, 9396, 9400-9401, 9410-9411, 9420, 9423-9425, 9430, 9440-9442, 9445, 9450-9451, 9460, 9505	0-3	254-261
	C71-C72	9383-9384, 9394, 9412, 9421, 9506	1
	C71-C72	9413, 9492-9493	0
	C00-C80	9390	0-3
	C70	8000-8001	0-3
	C70-C72	9530, 9538-9539	0-3
	C75.3	8000, 9362, 9395	0-3
61.1 Astrocytic tumors of CNS	C71-C72	9380-9382, 9385, 9400-9401, 9410-9411, 9420, 9423-9425, 9430, 9440-9442, 9445	0-3	254
61.1 Astrocytic tumors of CNS	C71-C72	9384, 9421	1	254
61.2 Oligodendroglial tumors of CNS	C71-C72	9450-9451, 9460	0-3	255
61.3 Ependymal tumors of CNS	C71-C72	9391-9393, 9396	0-3	256
61.3 Ependymal tumors of CNS	C71-C72	9383, 9394	1	256
61.4 Neuronal and mixed neuronal-glial tumors	C71-C72	9413, 9492-9493	0	257
	C71-C72	9412, 9505-9506	1
	C71-C72	9505	3
61.5 Choroid plexus carcinoma of CNS	C00-C80	9390	0-3	258
61.6 Malignant meningiomas	C70	8000-8001	0-3	259
61.6 Malignant meningiomas	C70-C72	9530, 9538-9539	0-3	259
61.7 Tumors of the pineal gland	C75.3	8000, 9362, 9395	0-3	260
61.8 Other tumors of central nervous system (CNS)^*	C71-C72	8000-8001	0-3	261
61.8 Other tumors of central nervous system (CNS)^*	C71-C72	9505	0, 2	261
62. Embryonal Tumors of CNS	C71-C72	9470-9478, 9480, 9490, 9500-9504, 9508	0-3	262-274
62.1 Medulloblastoma	C71-C72	9470	0-3	262
62.2 Desmoplastic nodular medulloblastoma	C71-C72	9471	0-3	263
62.3 Medulloblastoma, large cell/anaplastic	C71-C72	9474	0-3	264
62.4 Medulloblastoma, WNT-activated	C71-C72	9475	0-3	265
62.5 Medulloblastoma, SHH-activated and TP53-mutant	C71-C72	9476	0-3	266
62.6 Medulloblastoma, non-WNT/non-SHH	C71-C72	9477	0-3	267
62.7 CNS Embryonal tumor, NOSa	C71-C72	9473	0-3	268
62.8 CNS ganglioneuroblastoma	C71-C72	9490	0-3	269
62.9 CNS neuroblastoma	C71-C72	9500	0-3	270
62.10 CNS embryonal tumor with rhabdoid features	C71-C72	9508	0-3	271
62.11 Medulloepithelioma, NOS	C71-C72	9501	0-3	272
62.12 Embryonal tumor with multilayered rosettes, C19MC-related/NOS	C71-C72	9478	0-3	273
62.13 Other embryonal tumors of CNS^*	C71-C72	9472, 9480, 9502-9504	0-3	274
63 Lymphoid Diseases	C00-C80	9590-9591, 9596-9597, 9650-9655, 9659, 9661-9665, 9667, 9670-9671, 9673, 9675, 9678-9680, 9684, 9687-9691, 9695, 9698-9702, 9705, 9708-9709, 9712, 9714, 9716-9719, 9724-9729, 9731-9735, 9737-9738, 9760-9762, 9764, 9811-9818, 9820, 9823, 9826-9827, 9831-9837, 9940, 9948, 9970-9971	0-3	275-287
63.1 Hodgkin lymphoma, classical	C00-C80	9596, 9650-9655, 9661-9665, 9667	0-3	275
63.2 Hodgkin lymphoma nodular lymphocyte predominance	C00-C80	9659	0-3	276
63.3 Precursor B/T lymphoblastic leukemia/lymphoblastic lymphoma (and Burkitt)	C00-C80	9687, 9727-9729, 9811-9818, 9826, 9835-9837	0-3	277
63.4 T cutaneous lymphoma (Sezary syn, Mycosis fung)	C00-C80	9700-9701, 9709, 9718	0-3	278
63.5 Other T cell lymphomas and NK cell neoplasms	C00-C80	9702, 9705, 9708, 9714, 9716-9717, 9719, 9724-9726, 9827, 9831, 9834, 9948	0-3	279
63.6 Diffuse B lymphoma	C00-C80	9675, 9678-9680, 9684, 9735, 9737-9738	0-3	280
63.7 Follicular B lymphoma	C00-C80	9597, 9690-9691, 9695, 9698	0-3	281
63.8 Hairy cell leukemia	C00-C80	9940	0-3	282
63.9 Plasmacytoma/Multiple Myeloma (and Heavy chain diseases)	C00-C80	9731-9734, 9762	0-3	283
63.10 Other non Hodgkin, Mature B cell lymphoma	C00-C80	9670-9671, 9689, 9699, 9712, 9761, 9764, 9823, 9971	0-3	284
63.11 Mantle cell lymphoma	C00-C80	9673	0-3	285
63.12 Prolymphocytic leukemia, B cell	C00-C80	9832-9833	0-3	286
63.13 Other lymphoid diseases^*	C00-C80	9590-9591, 9688, 9760, 9820, 9970	0-3	287
64. Acute Myeloid Leukemia and Related Precursor Neoplasms	C00-C80	9801, 9805-9809, 9840, 9860-9861, 9865-9867, 9869-9874, 9891, 9895-9898, 9910-9911, 9920, 9930-9931, 9984, 9987	0-3	288-289
64.1 Acute promyelocytic leukemia (AML with t(15;17) with variants)	C00-C80	9866	0-3	288
64.2 AML	C00-C80	9801, 9805-9809, 9840, 9860-9861, 9865, 9867, 9869-9874, 9891, 9895-9898, 9910-9911, 9920, 9930-9931, 9984, 9987	0-3	289
65. Myeloid and Lymphoid Neoplasms	C00-C80	9800, 9965, 9966,9967	0-3	290
66. Myeloproliferative Neoplasms	C00-C80	9740-9742, 9863, 9875, 9950, 9960-9964, 9991-9992	0-3	291-293
66.1 Chronic myeloid leukemia	C00-C80	9863, 9875	0-3	291
66.2 Other myeloproliferative neoplasms	C00-C80	9950, 9960-9964, 9991-9992	0-3	292
66.3 Mast cell tumor	C00-C80	9740-9742	0-3	293
67. Myelodysplastic Syndrome and Myelodysplastic/myeloproliferative Diseases	C00-C80	9876, 9945-9946, 9975, 9980, 9982-9983, 9985-9986, 9989	0-3	294-298
67.1 Myelodysplastic syndrome with 5q syndrome	C00-C80	9986	0-3	294
67.2 Other myelodysplastic syndrome	C00-C80	9980, 9982-9983, 9985, 9989	0-3	295
67.3 Chronic Myelomonocytic leukemia	C00-C80	9945-9946	0-3	296
67.4 Atypical chronic myeloid leukemia BCR/ABL negative	C00-C80	9876	0-3	297
67.5 Other myelodysplastic syn and myelodysplastic/myeloproliferative diseases^*	C00-C80	9975	0-3	298
68. Histiocytic and Dendritic Cell Neoplasms	C00-C80	9750-9751, 9753-9759	0-3	299-300
68.1 Histiocytic malignancies	C00-C80	9750-9751, 9753-9754, 9756	0-3	299
68.2 Lymph node accessory cell tumors	C00-C80	9755, 9757-9759	0-3	300
69. Not Classified				999

⁽¹⁾Gatta G, Capocaccia R, Botta L, Mallone S, De Angelis R, Ardanaz E, et al. Burden and centralised treatment in Europe of rare tumours: results of RARECAREnet-a population-based study. Lancet Oncology. 2017;18(8):1022-39.
⁽²⁾Botta L, Gatta G, Trama A, Bernasconi A, Sharon E, Capocaccia R, et al. Incidence and survival of rare cancers in the US and Europe. Cancer Medicine. 2020;9(15):5632-42.
^* NOS category, not a clinical entity.