This is a document containing changes only. Do not use in place of the Solid Tumor Rules.

Other Sites - May Update

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Terms and Definitions

  • All histology tables: Behavior codes were removed unless a histology only occurs with one behavior code
  • Table 2: Histology Combination Codes
    • 8340 row: Example deleted
  • Table 4: Testis Histologies
    • 9064 row: Histologies in the example corrected to 9084
  • Table 6: Stomach Histologies
    • 8144/2 and 8144/3 consolidated to one row
  • Table 7: Small Intestine and Ampulla of Vater Histologies
    • 8144/2 and 8144/3 consolidated to one row
  • Table 9: Liver and Intrahepatic Bile Duct Histologies
    • 8470/2 and 8470/3 consolidated to one row
  • Table 10: Gallbladder and Extrahepatic Bile Duct Histologies
    • 8503/2 and 8503/3 consolidated to one row
  • Table 11: Pancreas Histologies
    • 8453/2 and 8453/3 consolidated to one row
    • 8503/2 and 8503/3 consolidated to one row
    • 8470/2 and 8470/3 consolidated to one row
  • Table 12: Thyroid Histologies
    • 8260 row: Oncocytic variant of PTC code corrected to 8342
  • Table 21: C412-C414, C418, C419 added

Multiple Primary Rules

  • M Rule: Abstract multiple primaries when separate/non-contiguous tumors are anaplastic carcinoma and any other histologies in the thyroid.
    • Note added: “This rule does not apply to multiple tumors that are anaplastic carcinoma and undifferentiated carcinoma.”
  • M Rule: Tumors with ICD-O-3 topography codes that differ only at the fourth character…
    • Bullet deleted (no longer applies to 2023+ cases): Peripheral nerves and autonomic nervous system (C47_) (Cases diagnosed 1/1/2007 to 12/31/2017 ONLY)
  • The “different subtypes/variants” M rule now comes before the “same row” M rule to be consistent with all other Solid Tumor modules (the order was switched).
  • M Rule: Abstract multiple primaries when separate/non-contiguous tumors are two or more different subtypes/variants…
    • Histology codes in the bullets were corrected

Other Sites - March Update

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Terms and Definitions

  • Table 1: Paired Organs and Sites with Laterality
    • Row added: “C444 Skin of Scalp and Neck”
    • Rows C443 and C445: “If midline, assign code 5” (corrected from code 9)
  • Table 2: Histology Combination Codes
    • 8255 row, note added: “Code 8255 does not apply to GYN primaries. Continue through the table to determine correct mixed histology code for GYN neoplasms.”
    • 8340 row: Note and example added.
  • Table 3: Prostate Histologies
    • Acinar adenocarcinoma 8140 row
      • Subtype/variant deleted: "Adenocarcinoma with neuroendocrine differentiation 8574/3" (this histology erroneously appeared twice in the table)
  • Table 4: Testis Histologies
    • Germ cell tumor, NOS 9064/3:
      • Note added: “The following teratomas are not reportable:
        • Teratoma, prepubertal type 9064/0
        • Teratoma, mature, prepubertal type 9064/0”
    • Row added: “Seminoma, NOS 9061/3”
  • Table 12: Thyroid Histologies
    • Carcinoma, anaplastic 8021/3 row
      • “Carcinoma, Undifferentiated 8020/3” moved from synonyms to subtypes/variants
    • Papillary thyroid carcinoma, NOS 8260/3 row
      • “And papillary microcarcinoma” added to note and synonyms
      • Subtype/variant deleted: Non-invasive encapsulated follicular variant of papillary thyroid carcinoma 8343/2
  • Table 14: Peritoneum Histologies
    • Added “as noted in the 5th Ed WHO Female Genital Tumors only” to the intro
  • Table 15: Fallopian Tube Histologies
    • Serous carcinoma, NOS 8441/3 row
      • Subtype/variant added: “Low-grade serous carcinoma 8460/3”
  • Table 17: Uterine Cervix Histologies
    • Germ cell tumor NOS 9064/3 row
      • Subtypes/variants added:
        • “Choriocarcinoma NOS 9100/3”
        • “Endodermal sinus tumor/Yolk sac tumor 9071/3”
    • Mucoepidermoid carcinoma 8430/3 row
      • Subtypes/variants deleted:
        • “Choriocarcinoma NOS 9100/3”
        • “Endodermal sinus tumor/Yolk sac tumor 9071/3”
  • Table 19: Vulva Histologies
    • Neuroendocrine tumor, NOS 8240/3 row
      • Subtype/variant added: “Neuroendocrine tumor, grade 2 8249/3”
      • Synonym removed: “Neuroendocrine tumor, grade 2”
  • Table 20: Soft Tissue Histologies
    • Note added: “Table 20 lists sarcomas arising in the soft tissue sites listed below only. Soft tissue neoplasms can arise in other organs. See the site-specific Solid Tumor Modules.”
  • Table 21: Bone Histologies
    • Chordoma, NOS 9370/3 row
      • Subtype/variant added: “Chondroid chordoma 9371/3”
    • Row added: “Undifferentiated high grade pleomorphic sarcoma of bone 8830/3”

Multiple Primary Rules

  • New M Rule:
    • “Abstract multiple primaries when separate/non-contiguous tumors are two or more different subtypes/variants in Column 3, Table 3-21 in the Equivalent Terms and Definitions.”

Histology Coding Rules

  • “Coding Histology” section
    • Example added to Instruction #2: “Endometrioid carcinoma with squamous differentiation has an ICD-O code of 8570/3”
  • New H Rule: “Code 8077/2 (squamous intraepithelial neoplasia, high grade) for the following:…”
  • New H Rule: “Code 8148/2 (glandular intraepithelial neoplasia, grade III) for the following:…”
  • H Rule: Code the histology when only one histologic type is identified.
    • Note 2 and Example added (former Note 2 moved to Note 3)
  • H Rule: Code papillary carcinoma, follicular variant of thyroid (8340) when there are multiple papillary and follicular carcinoma subtypes/variants…
    • Note added
  • H Rule: Code 8077/2 (Squamous intraepithelial neoplasia, high grade) for the following:
    • Bullet removed: “biliary intraepithelial neoplasia, high grade”