Statistics at a Glance

At a Glance

Estimated New Cases in 2021 1,898,160

% of All New Cancer Cases 100.0%

Estimated Deaths in 2021 608,570

% of All Cancer Deaths 100.0%

5-Year
Relative Survival

67.7% 2011–2017
Year Rate of New Cases — SEER 9 Rate of New Cases — SEER 13 Death Rate — U.S. 5-Year Relative Survival — SEER 9
Observed Modeled Trend Observed Modeled Trend Observed Modeled Trend Observed Modeled Trend
1975 400.44 395.88 - - 199.14 201.21 48.96% 49.01%
1976 407.41 400.75 - - 202.30 202.13 49.40% 49.32%
1977 407.72 405.67 - - 203.02 203.05 49.25% 49.63%
1978 407.31 410.65 - - 204.42 203.98 49.38% 49.94%
1979 412.50 415.69 - - 204.53 204.91 49.05% 50.25%
1980 418.12 420.80 - - 206.96 205.85 49.35% 50.56%
1981 425.29 425.97 - - 206.40 206.79 50.13% 50.87%
1982 424.49 431.20 - - 208.32 207.74 50.08% 51.17%
1983 431.11 436.49 - - 209.21 208.69 51.00% 51.48%
1984 440.01 441.85 - - 210.91 209.64 51.34% 51.78%
1985 448.97 447.28 - - 211.35 210.60 52.77% 52.93%
1986 451.37 452.77 - - 211.79 211.56 53.69% 54.07%
1987 468.14 458.33 - - 211.91 212.53 54.96% 55.19%
1988 464.06 463.96 - - 212.62 213.50 55.61% 56.29%
1989 468.00 469.66 - - 214.30 214.47 55.99% 57.38%
1990 482.16 482.90 - - 214.95 215.45 57.91% 58.45%
1991 503.16 496.52 - - 215.06 214.82 60.21% 59.51%
1992 510.82 510.51 503.43 503.17 213.46 214.19 62.01% 60.55%
1993 493.59 498.54 487.08 487.60 213.45 213.56 61.47% 61.16%
1994 483.74 486.84 475.43 472.51 211.74 211.26 61.23% 61.76%
1995 477.40 475.41 471.62 474.16 209.89 208.99 61.83% 62.36%
1996 479.63 479.68 473.34 475.80 207.00 206.74 62.80% 62.95%
1997 486.92 483.99 478.89 477.46 203.55 204.52 63.58% 63.53%
1998 488.86 488.34 480.54 479.12 200.82 202.32 64.30% 64.11%
1999 491.13 492.72 481.72 480.78 200.72 200.14 65.48% 64.68%
2000 487.07 491.89 475.57 479.79 198.79 197.99 66.26% 65.24%
2001 497.57 491.06 485.76 478.80 196.29 195.86 67.05% 65.80%
2002 496.04 490.24 481.80 477.81 194.36 193.75 67.56% 66.36%
2003 484.65 489.41 471.72 476.83 190.89 190.79 66.98% 66.90%
2004 486.06 488.59 473.60 475.84 186.84 187.88 67.64% 67.44%
2005 482.38 487.77 469.63 474.86 185.23 185.02 68.06% 67.97%
2006 486.65 486.95 471.06 473.88 182.03 182.19 68.91% 68.50%
2007 492.80 486.13 478.56 472.90 179.26 179.41 69.49% 69.02%
2008 486.33 485.31 472.14 471.93 176.32 176.68 69.38% 69.17%
2009 485.23 480.28 470.93 470.95 173.40 173.98 69.73% 69.32%
2010 476.32 475.30 462.02 461.63 171.75 171.33 69.63% 69.46%
2011 471.03 470.38 455.10 452.50 168.79 168.71 69.85% 69.61%
2012 458.79 465.51 442.78 443.55 166.42 166.14 69.13% 69.76%
2013 453.22 460.69 436.83 439.73 163.31 163.60 69.48% 69.91%
2014 451.31 455.91 433.65 435.95 161.44 161.11 - 70.05%
2015 451.87 451.19 433.79 432.20 158.91 158.65 - 70.20%
2016 450.68 446.52 432.46 428.49 156.03 156.23 - 70.35%
2017 447.96 441.89 428.60 424.80 152.61 152.60 - 70.49%
2018 435.76 437.31 415.83 421.15 149.04 149.05 - 70.63%

New cases come from SEER 13. Deaths come from U.S. Mortality.
All Races, Both Sexes. Rates are Age-Adjusted.
Modeled trend lines were calculated from the underlying rates using the Joinpoint Trend Analysis Software.

New cases are also referred to as incident cases in other publications. Rates of new cases are also referred to as incidence rates.


Rate of New Cases and Deaths per 100,000: The rate of new cases of cancer of any site was 450.5 per 100,000 men and women per year. The death rate was 155.5 per 100,000 men and women per year. These rates are age-adjusted and based on 2014–2018 cases and deaths.

Lifetime Risk of Developing Cancer: Approximately 39.2 percent of men and women will be diagnosed with cancer of any site at some point during their lifetime, based on 2016–2018 data.

Prevalence of This Cancer: In 2018, there were an estimated 16,353,421 people living with cancer of any site in the United States.

Did You Know? Video Series

Survival Statistics

How Many People Survive 5 Years Or More after Being Diagnosed with Cancer of Any Site?

Relative survival is an estimate of the percentage of patients who would be expected to survive the effects of their cancer. It excludes the risk of dying from other causes. Because survival statistics are based on large groups of people, they cannot be used to predict exactly what will happen to an individual patient. No two patients are entirely alike, and treatment and responses to treatment can vary greatly.

67.7%

5-Year
Relative Survival

67.7%

Based on data from SEER 18 2011–2017. Gray figures represent those who have died from cancer of any site. Green figures represent those who have survived 5 years or more.

New Cases and Deaths

How Common Is This Cancer?

Rank Common Types of Cancer Estimated New
Cases 2021
Estimated
Deaths 2021
1. Breast Cancer (Female) 281,550 43,600
2. Prostate Cancer 248,530 34,130
3. Lung and Bronchus Cancer 235,760 131,880
4. Colorectal Cancer 149,500 52,980
5. Melanoma of the Skin 106,110 7,180
6. Bladder Cancer 83,730 17,200
7. Non-Hodgkin Lymphoma 81,560 20,720
8. Kidney and Renal Pelvis Cancer 76,080 13,780
9. Uterine Cancer 66,570 12,940
10. Leukemia 61,090 23,660
- - -
Cancer of Any Site 1,898,160 608,570

In 2021, it is estimated that there will be 1,898,160 new cases of cancer of any site and an estimated 608,570 people will die of this disease.

Who Gets This Cancer?

Overall cancer incidence rates are higher among men than women. Among racial/ethnic groups, there are more new cases among African American men and white women and fewer new cases among Asian/Pacific Islanders of both sexes. The rate of new cases of cancer of any site was 450.5 per 100,000 men and women per year based on 2014–2018 cases, age-adjusted.

Rate of New Cases per 100,000 Persons by Race/Ethnicity & Sex: Cancer of Any Site
Males
All Races 489.2
White 495.8
Black 518.9
Asian/Pacific Islander 309.1
American Indian/Alaska Native 326.7
Hispanic 375.3
Non-Hispanic 506.7
Females
All Races 425.6
White 439.5
Black 396.4
Asian/Pacific Islander 311.5
American Indian/Alaska Native 311.1
Hispanic 348.4
Non-Hispanic 438.6

SEER 21 2014–2018, Age-Adjusted

Percent of New Cases by Age Group: Cancer of Any Site
Age Range Percent of New Cases
<20 1.0%
20–34 2.8%
35–44 4.7%
45–54 12.0%
55–64 24.3%
65–74 28.7%
75–84 18.5%
>84 8.1%

Cancer of any site is most frequently diagnosed among people aged 65–74.

Median Age
At Diagnosis

66

SEER 21 2014–2018, All Races, Both Sexes

Who Dies From This Cancer?

Death rates for cancer are higher among the middle-aged and elderly populations. The death rate was 155.5 per 100,000 men and women per year based on 2014–2018 deaths, age-adjusted.

Death Rate per 100,000 Persons by Race/Ethnicity & Sex: Cancer of Any Site
Males
All Races 185.5
White 185.9
Black 221.1
Asian/Pacific Islander 114.6
American Indian/Alaska Native 169.3
Hispanic 134.0
Non-Hispanic 190.7
Females
All Races 133.5
White 134.3
Black 150.5
Asian/Pacific Islander 84.6
American Indian/Alaska Native 120.1
Hispanic 94.6
Non-Hispanic 137.6

U.S. 2014–2018, Age-Adjusted

Percent of Deaths by Age Group: Cancer of Any Site
Age Range Percent of Deaths
<20 0.3%
20–34 0.8%
35–44 1.8%
45–54 6.9%
55–64 19.3%
65–74 27.7%
75–84 26.0%
>84 17.2%

The percent of cancer of any site deaths is highest among people aged 65–74.

Median Age
At Death

72

U.S. 2014–2018, All Races, Both Sexes

Trends in Rates

Changes Over Time

Keeping track of new cases, deaths, and survival over time (trends) can help scientists understand whether progress is being made and where additional research is needed to address challenges, such as improving screening or finding better treatments.

Using statistical models for analysis, age-adjusted rates for new cancer of any site cases have been falling on average 1.0% each year over 2009–2018. Age-adjusted death rates have been falling on average 1.7% each year over 2009–2018. 5-year relative survival trends are shown below.

Interactive Statistics with SEER*Explorer

With SEER*Explorer, you can...
  • Create custom graphs and tables
  • Download data and images
  • Share links to results

SEER*Explorer is an interactive website that provides easy access to a wide range of SEER cancer statistics. It provides detailed statistics for a cancer site by gender, race, calendar year, age, and for a selected number of cancer sites, by stage and histology.

Explore Additional Cancer of Any Site Statistics

More About This Cancer

More Information

Here are some resources for learning more about cancer.

References

All statistics in this report are based on statistics from SEER and the Centers for Disease Control and Prevention's National Center for Health Statistics. Most can be found within SEER*Explorer.

Suggested Citation

All material in this report is in the public domain and may be reproduced or copied without permission; citation as to source, however, is appreciated.

SEER Cancer Stat Facts: Cancer of Any Site. National Cancer Institute. Bethesda, MD, https://seer.cancer.gov/statfacts/html/all.html

These stat facts focus on population statistics that are based on the U.S. population. Because these statistics are based on large groups of people, they cannot be used to predict exactly what will happen to an individual patient. To see tailored statistics, browse SEER*Explorer. To see statistics for a specific state, go to the State Cancer Profiles.

The statistics presented in these stat facts are based on the most recent data available, most of which can be found in SEER*Explorer. In some cases, different year spans may be used.

Estimates of new cases and deaths for 2021 are projections made by the American Cancer Society (ACS), based on earlier reported data.

Cancer is a complex topic. There is a wide range of information available. These stat facts do not address causes, symptoms, diagnosis, treatment, follow-up care, or decision making, although links are provided to information in many of these areas.