SEER*Explorer

Preliminary Trends and Rates are also available in SEER*Explorer.

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Caution is advised when interpreting these figures, as these are preliminary results and are subject to change with the addition of data from future case submissions.

Estimates are available for 24 cancer sites by sex and for both sexes combined. Due to less stability of the preliminary estimates by race and ethnicity, at this time, estimates are only available for all races and ethnicities combined.

To assist users in understanding the preliminary estimates, three graphs are presented for each cancer site and sex combination (60 total data series adjusting for single sex cancer sites). For each graph, two series are presented: the observed rates (not adjusted for the undercount), and rates adjusted for the undercount of cases (called "delay-adjusted" rates). For each graph, by comparing the observed to delay-adjusted rates for the most recent years, users can see the magnitude of the undercount. While the delay-adjustment varies by cancer site, the adjustment for the most recent year of diagnosis averages around 3% for the official April release of the data, while the adjustment for the preliminary data based on the February submission averages around 9%.

  • Graph 1: Preliminary Estimates (Selected Registries 2000-2023)

    Estimates are based on the February 2025 data submission and include only registries that met three criteria: (1) sufficient historical February submission data, (2) at least 95% case completeness for diagnoses in 2023, and (3) consistent historical ratios of the initial February to subsequent November case counts for recent diagnosis years. Registries that meet these three criteria are: Alaska Native Tumor Registry, Connecticut, Georgia Center for Cancer Statistics (Atlanta, Greater Georgia, Rural Georgia), Greater Bay (San Francisco and San Jose), Hawaii, Iowa, Kentucky, Louisiana, New Jersey, New York, Seattle and Utah. These registries represent approximately 23% of the U.S. population, and about 50% of the population covered by the SEER 21 registries in the Official Release.

  • Graph 2: Selected Registries (2000-2022)

    Estimates based on the November 2024 data submission and limited to the same registries included in the preliminary estimates.

    By comparing the direction and statistical significance of the final Joinpoint segment for trends based on delay-adjusted rates between Graph1 and Graph 2, users can determine cancer site/sex combinations where the addition of the new 2023 incidence data may suggest a change in the trend for this cancer for the selected registries. Of the 60 cancer site by sex combinations, there were 14 suggestions of new trends. Caution is advised because not all of these trends will be confirmed when the official November 2025 data are released in April 2026.

  • Graph 3: SEER 21 Registries (2000-2022) - NCI Official Statistics

    Estimates based on the November 2024 submission and released in April 2025. This series includes the full set of SEER 21 registries covering approximately 46% of the U.S. population.

    By comparing the direction and statistical significance of the final Joinpoint segment for trends based on delay-adjusted rates between Graph 2 and Graph 3, users can determine cancer site/sex combinations where differences in geography between the selected registries and the full official set of SEER 21 registries suggest different characterizations of the most recent trend. Of the 60 cancer site by sex combination, there were 8 combinations where the differences in geography between the selected registries and SEER 21 registries resulted in new trends for the final Joinpoint segment for cases diagnosed through 2022.

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