Statistics at a Glance

At a Glance

Estimated New Cases in 2020 19,940

% of All New Cancer Cases 1.1%

Estimated Deaths in 2020 11,180

% of All Cancer Deaths 1.8%

5-Year
Relative Survival

28.7% 2010–2016
Year Rate of New Cases — SEER 9 Rate of New Cases — SEER 13 Death Rate — U.S. 5-Year Relative Survival — SEER 9
Observed Modeled Trend Observed Modeled Trend Observed Modeled Trend Observed Modeled Trend
1975 3.43 3.50 - - 2.54 2.57 6.40% 8.64%
1976 3.50 3.47 - - 2.59 2.56 4.90% 8.87%
1977 3.51 3.43 - - 2.57 2.55 7.53% 9.11%
1978 3.42 3.39 - - 2.54 2.55 7.90% 9.35%
1979 3.32 3.36 - - 2.54 2.54 8.35% 9.59%
1980 3.14 3.32 - - 2.55 2.53 6.97% 9.83%
1981 3.17 3.29 - - 2.47 2.48 8.34% 10.08%
1982 3.42 3.25 - - 2.41 2.43 8.61% 10.34%
1983 3.21 3.22 - - 2.35 2.38 8.83% 10.59%
1984 3.30 3.18 - - 2.36 2.33 8.69% 10.85%
1985 3.33 3.15 - - 2.33 2.28 13.38% 11.12%
1986 3.00 3.11 - - 2.25 2.24 10.19% 11.38%
1987 3.02 3.08 - - 2.16 2.19 9.67% 11.65%
1988 3.03 3.05 - - 2.13 2.15 11.71% 12.21%
1989 3.20 3.11 - - 2.19 2.18 13.45% 12.78%
1990 3.04 3.18 - - 2.21 2.21 11.59% 13.36%
1991 3.33 3.25 - - 2.24 2.24 13.04% 13.96%
1992 3.22 3.32 3.32 3.36 2.29 2.27 17.16% 14.57%
1993 3.45 3.39 3.45 3.42 2.26 2.30 16.62% 15.19%
1994 3.46 3.47 3.49 3.48 2.29 2.33 14.86% 15.83%
1995 3.66 3.54 3.64 3.55 2.40 2.36 17.58% 16.47%
1996 3.47 3.62 3.47 3.62 2.44 2.39 17.40% 17.13%
1997 3.53 3.70 3.66 3.69 2.43 2.42 17.93% 17.80%
1998 3.93 3.78 3.89 3.76 2.43 2.46 16.84% 18.48%
1999 3.73 3.86 3.76 3.83 2.52 2.55 18.82% 19.17%
2000 4.05 3.94 3.97 3.90 2.66 2.65 17.19% 19.86%
2001 4.06 3.85 3.97 3.97 2.75 2.75 22.63% 20.57%
2002 3.63 3.76 3.63 3.74 2.76 2.76 22.79% 21.29%
2003 3.60 3.67 3.59 3.53 2.80 2.77 23.59% 22.02%
2004 3.42 3.58 3.40 3.32 2.78 2.78 25.09% 22.75%
2005 3.59 3.50 3.49 3.44 2.76 2.79 26.08% 23.50%
2006 3.54 3.41 3.52 3.56 2.80 2.80 25.90% 24.25%
2007 3.55 3.58 3.58 3.68 2.77 2.81 24.68% 25.00%
2008 3.83 3.74 3.82 3.80 2.83 2.82 24.87% 25.77%
2009 3.63 3.92 3.76 3.93 2.87 2.83 28.48% 26.53%
2010 4.24 4.10 4.16 4.07 2.79 2.82 29.87% 27.31%
2011 4.21 4.30 4.15 4.21 2.85 2.82 28.22% 28.09%
2012 4.59 4.50 4.43 4.35 2.78 2.81 30.56% 28.87%
2013 4.49 4.46 4.35 4.32 2.79 2.80 - 29.66%
2014 4.41 4.42 4.37 4.28 2.81 2.79 - 30.45%
2015 4.27 4.38 4.15 4.25 2.72 2.78 - 31.25%
2016 4.38 4.34 4.21 4.22 2.80 2.78 - 32.05%
2017 4.32 4.30 4.21 4.18 2.79 2.77 - 32.85%

New cases come from SEER 13. Deaths come from U.S. Mortality.
All Races, Both Sexes. Rates are Age-Adjusted.
Modeled trend lines were calculated from the underlying rates using the Joinpoint Trend Analysis Software.

New cases are also referred to as incident cases in other publications. Rates of new cases are also referred to as incidence rates.


Rate of New Cases and Deaths per 100,000: The rate of new cases of acute myeloid leukemia was 4.3 per 100,000 men and women per year. The death rate was 2.8 per 100,000 men and women per year. These rates are age-adjusted and based on 2013–2017 cases and deaths.

Lifetime Risk of Developing Cancer: Approximately 0.5 percent of men and women will be diagnosed with acute myeloid leukemia at some point during their lifetime, based on 2015–2017 data.

Prevalence of This Cancer: In 2017, there were an estimated 64,512 people living with acute myeloid leukemia in the United States.

Did You Know? Video Series

Survival Statistics

How Many People Survive 5 Years Or More after Being Diagnosed with Acute Myeloid Leukemia?

Relative survival is an estimate of the percentage of patients who would be expected to survive the effects of their cancer. It excludes the risk of dying from other causes. Because survival statistics are based on large groups of people, they cannot be used to predict exactly what will happen to an individual patient. No two patients are entirely alike, and treatment and responses to treatment can vary greatly.

28.7%

5-Year
Relative Survival

28.7%

Based on data from SEER 18 2010–2016. Gray figures represent those who have died from acute myeloid leukemia. Green figures represent those who have survived 5 years or more.

New Cases and Deaths

How Common Is This Cancer?

Rank Common Types of Cancer Estimated New
Cases 2020
Estimated
Deaths 2020
1. Breast Cancer (Female) 276,480 42,170
2. Lung and Bronchus Cancer 228,820 135,720
3. Prostate Cancer 191,930 33,330
4. Colorectal Cancer 147,950 53,200
5. Melanoma of the Skin 100,350 6,850
6. Bladder Cancer 81,400 17,980
7. Non-Hodgkin Lymphoma 77,240 19,940
8. Kidney and Renal Pelvis Cancer 73,750 14,830
9. Uterine Cancer 65,620 12,590
10. Leukemia 60,530 23,100
- - -
Acute Myeloid Leukemia 19,940 11,180

Acute myeloid leukemia represents 1.1% of all new cancer cases in the U.S.

1.1%

In 2020, it is estimated that there will be 19,940 new cases of acute myeloid leukemia and an estimated 11,180 people will die of this disease.

Who Gets This Cancer?

Acute myeloid leukemia is more common in older adults and among men compared to women. AML is a relatively rare disease. The rate of new cases of acute myeloid leukemia was 4.3 per 100,000 men and women per year based on 2013–2017 cases, age-adjusted.

Rate of New Cases per 100,000 Persons by Race/Ethnicity & Sex: Acute Myeloid Leukemia (AML)
Males
All Races 5.2
White 5.4
Black 4.4
Asian/Pacific Islander 4.1
American Indian/Alaska Native 2.9
Hispanic 4.2
Non-Hispanic 5.4
Females
All Races 3.6
White 3.7
Black 3.3
Asian/Pacific Islander 2.9
American Indian/Alaska Native 1.9
Hispanic 3.2
Non-Hispanic 3.6

SEER 21 2013–2017, Age-Adjusted

Percent of New Cases by Age Group: Acute Myeloid Leukemia
Age Range Percent of New Cases
<20 4.5%
20–34 5.6%
35–44 5.1%
45–54 9.2%
55–64 16.7%
65–74 25.5%
75–84 22.5%
>84 10.9%

Acute myeloid leukemia is most frequently diagnosed among people aged 65–74.

Median Age
At Diagnosis

68

SEER 21 2013–2017, All Races, Both Sexes

Who Dies From This Cancer?

Death rates from acute myeloid leukemia are higher among older adults, or those 65 and older. People with leukemia have many treatment options, and treatment for leukemia can often control the disease and its symptoms. The death rate was 2.8 per 100,000 men and women per year based on 2013–2017 deaths, age-adjusted.

Death Rate per 100,000 Persons by Race/Ethnicity & Sex: Acute Myeloid Leukemia (AML)
Males
All Races 3.6
White 3.7
Black 2.7
Asian/Pacific Islander 2.6
American Indian/Alaska Native 1.9
Hispanic 2.4
Non-Hispanic 3.7
Females
All Races 2.2
White 2.2
Black 1.9
Asian/Pacific Islander 1.5
American Indian/Alaska Native 1.5
Hispanic 1.6
Non-Hispanic 2.2

U.S. 2013–2017, Age-Adjusted

Percent of Deaths by Age Group: Acute Myeloid Leukemia
Age Range Percent of Deaths
<20 1.7%
20–34 2.4%
35–44 2.6%
45–54 6.1%
55–64 15.1%
65–74 28.1%
75–84 29.6%
>84 14.4%

The percent of acute myeloid leukemia deaths is highest among people aged 75–84.

Median Age
At Death

73

U.S. 2013–2017, All Races, Both Sexes

Trends in Rates

Changes Over Time

Keeping track of new cases, deaths, and survival over time (trends) can help scientists understand whether progress is being made and where additional research is needed to address challenges, such as improving screening or finding better treatments.

Using statistical models for analysis, age-adjusted rates for new acute myeloid leukemia cases have been rising on average 1.5% each year over the last 10 years. Age-adjusted death rates have been stable over 2008–2017. 5-year relative survival trends are shown below.

Interactive Statistics with SEER*Explorer

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  • Create custom graphs and tables
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SEER*Explorer is an interactive website that provides easy access to a wide range of SEER cancer statistics. It provides detailed statistics for a cancer site by gender, race, calendar year, age, and for a selected number of cancer sites, by stage and histology.

Explore Additional Acute Myeloid Leukemia Statistics

More About This Cancer

Cancer and the Blood

Figure: Blood Cells Maturing from Stem Cells

Figure: Stem cells maturing into one of three types of mature blood cells: red blood cells, platelets, and white blood cells. Precursor cells are also shown: stem cells, myeloid blasts, lymphoid stem cells, and lymphoid blasts.

Leukemia is cancer that starts in the tissue that forms blood. Most blood cells develop from cells in the bone marrow called stem cells. In a person with leukemia, the bone marrow makes abnormal white blood cells. The abnormal cells are leukemia cells. Unlike normal blood cells, leukemia cells don't die when they should. They may crowd out normal white blood cells, red blood cells, and platelets. This makes it hard for normal blood cells to do their work. The four main types of leukemia are:

There is no standard staging system for leukemia. The disease is described as untreated, in remission, or recurrent.

Additional Information

More Information

Here are some resources for learning more about leukemia.

References

All statistics in this report are based on statistics from SEER and the Centers for Disease Control and Prevention's National Center for Health Statistics. Most can be found within:

Howlader N, Noone AM, Krapcho M, Miller D, Brest A, Yu M, Ruhl J, Tatalovich Z, Mariotto A, Lewis DR, Chen HS, Feuer EJ, Cronin KA (eds). SEER Cancer Statistics Review, 1975–2017, National Cancer Institute. Bethesda, MD, https://seer.cancer.gov/csr/1975_2017/, based on November 2019 SEER data submission, posted to the SEER web site, April 2020.

Suggested Citation

All material in this report is in the public domain and may be reproduced or copied without permission; citation as to source, however, is appreciated.

SEER Cancer Stat Facts: Acute Myeloid Leukemia. National Cancer Institute. Bethesda, MD, https://seer.cancer.gov/statfacts/html/amyl.html

These stat facts focus on population statistics that are based on the U.S. population. Because these statistics are based on large groups of people, they cannot be used to predict exactly what will happen to an individual patient. To see tailored statistics, browse the SEER Cancer Statistics Review. To see statistics for a specific state, go to the State Cancer Profiles.

The statistics presented in these stat facts are based on the most recent data available, most of which can be found in the SEER Cancer Statistics Review. In some cases, different year spans may be used.

Estimates of new cases and deaths for 2020 are projections made by the American Cancer Society (ACS), based on earlier reported data.

Cancer is a complex topic. There is a wide range of information available. These stat facts do not address causes, symptoms, diagnosis, treatment, follow-up care, or decision making, although links are provided to information in many of these areas.