Statistics at a Glance

At a Glance

Breast, lung and bronchus, prostate, and colorectal cancers account for almost 50% of all new cancer cases in the United States. Lung and bronchus, colorectal, pancreatic, and breast cancers are responsible for nearly 50% of all deaths.

New Cancer Cases, 2019
Breast 271,270 (15%)
Lung & Bronchus 228,150 (13%)
Prostate 174,650 (10%)
Colon and rectum 145,600 (8%)
Other 942,780 (53%)
Cancer Deaths, 2019
Lung & Bronchus 142,670 (24%)
Colon and rectum 51,020 (8%)
Pancreas 45,750 (8%)
Breast 42,260 (7%)
Other 325,180 (54%)

How Many People Are Diagnosed with Cancer Each Year?

In 2019, roughly 1.8 million people will be diagnosed with cancer in the United States. An estimated 268,600 women and 2,670 men will be diagnosed with breast cancer, which makes it the most common cancer diagnosis. Lung and bronchus cancer is the second most common cancer diagnosis with an estimated 228,150 new cases. Prostate cancer is the leading cancer diagnosis among men and the third most common diagnosis overall with 174,650 expected cases.

The top 12 most common cancer sites, shown below, will account for more than three quarters of all new cancer cases.

Male
Breast 2,670
Lung & Bronchus 116,440
Prostate 174,650
Colorectal 78,500
Melanoma of the Skin 57,220
Urinary Bladder 61,700
Non-Hodgkin Lymphoma 41,090
Kidney and Renal Pelvis 44,120
Uterus 0
Leukemia 35,920
Pancreas 29,940
Thyroid 14,260
Female
Breast 268,600
Lung & Bronchus 111,710
Prostate 0
Colorectal 67,100
Melanoma of the Skin 39,260
Urinary Bladder 18,770
Non-Hodgkin Lymphoma 33,110
Kidney and Renal Pelvis 29,700
Corpus & Uterus, NOS 61,880
Leukemia 25,860
Pancreas 26,830
Thyroid 37,810

How Many People Die of Cancer Each Year?

In 2019, an estimated 606,880 people will die of cancer in the United States. Lung and bronchus cancer is responsible for the most deaths with 142,670 people expected to die from this disease. That is nearly three times the 51,020 deaths due to colorectal cancer, which is the second most common cause of cancer death. Pancreatic cancer is the third deadliest cancer, causing 45,750 deaths.

The eight deadliest cancer sites, shown below, will account for almost two-thirds of all expected cancer deaths.

Male
Lung and bronchus 76,650
Colon and rectum 27,640
Pancreas 23,800
Breast 500
Liver & Intrahepatic Bile Duct 21,600
Prostate 31,620
Leukemia 13,150
Non-Hodgkin Lymphoma 11,510
Female
Lung and bronchus 66,020
Colon and rectum 23,380
Pancreas 21,950
Breast 41,760
Liver & Intrahepatic Bile Duct 10,180
Prostate 0
Leukemia 9,690
Non-Hodgkin Lymphoma 8,460

New Cases, Deaths, and Survival

How Do Cancer Rates Compare?

For comparison purposes, new cases and deaths are generally expressed as a rate - the number per 100,000 in the total population. The rate of new cases is known as cancer incidence, and the death rate as mortality. Note that total population changes depending on what group you are looking at, so, for instance, incidence for females is the rate per 100,000 females in the U.S.

The table below gives the predicted number of new cases and deaths in 2019, the incidence and mortality rates over the most recent five years of data, and the five-year relative survival rate, representing the percent surviving cancer 5-years after diagnosis.

You can sort on any column by clicking the header.

Site Estimated New Cases (2019) Incidence Rates (2012-2016) Estimated Deaths (2019) Mortality Rates (2012-2016) Survival (%) (2009-2015)
Anus 8,300 1.9 1,280 0.3 68.3
Bone and Joint 3,500 1.0 1,660 0.4 66.2
Bladder 80,470 20.1 17,670 4.4 77.1
Brain and Other Nervous System 23,820 6.4 17,760 4.4 32.9
Breast 271,270 68.4 42,260 11.4 89.8
Cervix Uteri 13,170 7.3 4,250 2.3 65.8
Colon and Rectum 145,600 38.6 51,020 14.2 64.4
Esophagus 17,650 4.3 16,080 4.0 19.9
Hodgkin Lymphoma 8,110 2.7 1,000 0.3 86.6
Kidney and Renal Pelvis 73,820 16.1 14,770 3.8 74.8
Larynx 12,410 3.0 3,760 1.0 60.3
Leukemia 61,780 14.1 22,840 6.5 62.7
Liver and Intrahepatic Bile Duct 42,030 8.8 31,780 6.5 18.4
Lung and Bronchus 228,150 54.9 142,670 41.9 19.4
Melanoma of the Skin 96,480 22.2 7,230 2.5 92.2
Myeloma 32,110 6.9 12,960 3.3 52.2
Non-Hodgkin Lymphoma 74,200 19.6 19,970 5.6 72.0
Oral Cavity and Pharynx 53,000 11.3 10,860 2.5 65.3
Ovary 22,530 11.4 13,980 7.0 47.6
Pancreas 56,770 12.9 45,750 11.0 9.3
Prostate 174,650 109.5 31,620 19.2 98.0
Small Intestine 10,590 2.4 1,590 0.4 68.0
Stomach 27,510 7.4 11,140 3.1 31.5
Testis 9,560 5.9 410 0.3 95.2
Thyroid 52,070 15.8 2,170 0.5 98.2
Uterus 61,880 27.5 12,160 4.7 81.2
Vulva 6,070 2.5 1,280 0.5 71.1
Site Estimated New Cases (2019) Incidence Rates (2012-2016) Estimated Deaths (2019) Mortality Rates (2012-2016) Survival (%) (2009-2015)
Anus 5,530 2.2 760 0.3 72.0
Bone and Joint 1,470 0.8 700 0.3 69.1
Bladder 18,770 8.7 4,800 2.1 73.2
Brain and Other Nervous System 10,410 5.4 7,850 3.6 34.6
Breast 268,600 127.5 41,760 20.6 89.9
Cervix Uteri 13,170 7.3 4,250 2.3 65.8
Colon and Rectum 67,100 33.9 23,380 11.9 64.9
Esophagus 3,900 1.8 3,060 1.5 21.5
Hodgkin Lymphoma 3,540 2.3 410 0.2 87.8
Kidney and Renal Pelvis 29,700 10.9 4,950 2.3 75.9
Larynx 2,550 1.1 750 0.4 57.8
Leukemia 25,860 10.9 9,690 4.9 61.5
Liver and Intrahepatic Bile Duct 12,550 4.7 10,180 3.9 19.5
Lung and Bronchus 111,710 48.9 66,020 34.4 23.0
Melanoma of the Skin 39,260 17.5 2,490 1.5 94.6
Myeloma 13,980 5.6 5,970 2.7 52.4
Non-Hodgkin Lymphoma 33,110 16.2 8,460 4.4 73.7
Oral Cavity and Pharynx 14,860 6.4 2,890 1.3 67.1
Ovary 22,530 11.4 13,980 7.0 47.6
Pancreas 26,830 11.5 21,950 9.6 9.2
Prostate - - - - -
Small Intestine 4,980 2.1 700 0.3 68.2
Stomach 10,280 5.3 4,340 2.3 35.7
Testis - - - - -
Thyroid 37,810 23.3 1,150 0.5 98.9
Uterus 61,880 27.5 12,160 4.7 81.2
Vulva 6,070 2.5 1,280 0.5 71.1
Site Estimated New Cases (2019) Incidence Rates (2012-2016) Estimated Deaths (2019) Mortality Rates (2012-2016) Survival (%) (2009-2015)
Anus 2,770 1.6 520 0.2 61.9
Bone and Joint 2,030 1.1 960 0.5 64.0
Bladder 61,700 35.2 12,870 7.6 78.3
Brain and Other Nervous System 13,410 7.5 9,910 5.4 31.6
Breast 2,670 1.2 500 0.3 83.6
Cervix Uteri - - - - -
Colon and Rectum 78,500 44.2 27,640 16.9 64.0
Esophagus 13,750 7.3 13,020 7.1 19.4
Hodgkin Lymphoma 4,570 3.0 590 0.4 85.6
Kidney and Renal Pelvis 44,120 22.1 9,820 5.5 74.2
Larynx 9,860 5.2 3,010 1.8 60.9
Leukemia 35,920 18.1 13,150 8.8 63.6
Liver and Intrahepatic Bile Duct 29,480 13.6 21,600 9.6 18.0
Lung and Bronchus 116,440 63.0 76,650 51.6 16.1
Melanoma of the Skin 57,220 28.8 4,740 3.7 90.4
Myeloma 18,130 8.7 6,990 4.2 52.1
Non-Hodgkin Lymphoma 41,090 23.9 11,510 7.3 70.7
Oral Cavity and Pharynx 38,140 17.0 7,970 3.9 64.6
Ovary - - - - -
Pancreas 29,940 14.6 23,800 12.6 9.4
Prostate 174,650 109.5 31,620 19.2 98.0
Small Intestine 5,610 2.7 890 0.5 67.9
Stomach 17,230 10.0 6,800 4.2 28.7
Testis 9,560 5.9 410 0.3 95.2
Thyroid 14,260 8.0 1,020 0.5 95.7
Uterus - - - - -
Vulva - - - - -

How Do the Most Common Cancers Compare by Race/Ethnicity?

The rate and type of cancer diagnosis varies significantly by race and ethnicity. The graph below shows the incidence (new cases) rate and rank, by race and ethnicity, for the four most commonly diagnosed cancers.

Site All Races White Black API AI/AN Hispanic
Female Breast 127.5 130.5 124.0 100.1 79.5 97.2
Colon and rectum 38.6 38.1 44.6 31.8 39.3 33.7
Lung & Bronchus 54.9 56.7 56.2 36.0 37.8 29.1
Prostate 109.5 101.9 176.7 55.6 55.4 93.4

a Asian & Pacific Islander, b American Indian / Alaska Native

Cancer death rates, or mortality rates, also vary significantly by race and ethnicity. The graph below shows the mortality rate, by race and ethnicity, for the five most commonly diagnosed cancers.

Site All Races White Black API AI/AN Hispanic
Female Breast 20.6 20.1 28.1 11.2 14.3 14.2
Colon and rectum 14.2 13.8 18.9 9.8 15.6 11.2
Lung & Bronchus 41.9 42.7 44.3 22.7 34.8 18.3
Pancreas 11.0 10.9 13.3 7.6 8.9 8.5
Prostate 19.2 18.0 38.9 8.6 19.2 15.8

a Asian & Pacific Islander, b American Indian / Alaska Native

Trends in Rates

What Are the Recent Trends in Rates of New Cancer Cases?

Between 2012 and 2016, overall cancer incidence rates decreased among men and remained stable among women. During this period, nine of the 19 most common cancers in men and ten of the 21 most common cancers in women showed statistically significant decreases in incidence. For both men and women, laryngeal cancer showed the greatest decrease.

National Incidence Trends
Male
Thyroid 1.9*
Liver and Intrahepatic Bile Duct 1.4*
Melanoma of the Skin 1.4*
Oral Cavity and Pharynx 1.0*
Testis 0.8*
Kidney and Renal Pelvis 0.5*
Pancreas 0.4*
Myeloma 0.2
Leukemia 0.0
Brain and Other Nervous System -0.4*
Non-Hodgkin Lymphoma -0.5*
Stomach -1.4*
Esophagus -1.4*
Bladder -1.5*
Hodgkin Lymphoma -1.6*
Colon and Rectum -1.6*
All Sites -2.0*
Prostate -2.7
Lung and Bronchus -2.9*
Larynx -3.0*
Female
Melanoma of the Skin 1.6*
Liver and Intrahepatic Bile Duct 1.3
Uterus 1.2*
Myeloma 1.1*
Pancreas 0.7*
Cervix Uteri 0.5
Breast 0.3*
Oral Cavity and Pharynx 0.3*
Kidney and Renal Pelvis 0.3
All Sites 0.0
Thyroid -0.3
Non-Hodgkin Lymphoma -0.4*
Brain and Other Nervous System -0.4*
Stomach -0.6*
Leukemia -0.7
Bladder -1.0*
Colon and Rectum -1.0*
Hodgkin Lymphoma -1.2*
Lung and Bronchus -1.5*
Ovary -1.6*
Esophagus -1.6*
Larynx -2.3*

What Are the Recent Trends in Cancer Death Rates?

Between 2012 and 2016, overall age-adjusted mortality decreased on average 1.8 percent per year for men and 1.4 percent for women. During this period, twelve of the 19 most common cancers in men and fifteen of the 21 most common cancers in women showed statistically significant decreases in mortality. Thyroid cancer showed the greatest increase in mortality among men. Uterine cancer showed the greatest increase in mortality among women.

National Mortality Trends
Male
Thyroid 1.1*
Liver and Intrahepatic Bile Duct 1.1*
Oral Cavity and Pharynx 1.0*
Brain and Other Nervous System 0.6*
Pancreas 0.3*
Testis 0.0
Bladder -0.3*
Kidney and Renal Pelvis -0.8*
Myeloma -0.9*
Prostate -0.9
Esophagus -1.1*
Stomach -1.7*
All Sites -1.8*
Non-Hodgkin Lymphoma -2.0*
Colon and Rectum -2.0*
Larynx -2.5*
Leukemia -2.6*
Hodgkin Lymphoma -2.7*
Lung and Bronchus -4.2*
Melanoma of the Skin -5.0*
Female
Uterus 2.1*
Liver and Intrahepatic Bile Duct 1.9*
Oral Cavity and Pharynx 1.9
Brain and Other Nervous System 0.5*
Thyroid 0.3
Pancreas 0.2*
Bladder -0.5*
Cervix Uteri -0.7*
Leukemia -1.3*
All Sites -1.4*
Kidney and Renal Pelvis -1.4*
Breast -1.5*
Colon and Rectum -1.5*
Esophagus -1.6*
Stomach -1.7*
Myeloma -1.7*
Larynx -2.3*
Ovary -2.3*
Non-Hodgkin Lymphoma -2.7*
Lung and Bronchus -3.1*
Melanoma of the Skin -5.0*
Hodgkin Lymphoma -5.2*

Additional Information

Average annual percent change (AAPC) is the year-to-year change averaged over a period of time, in this case, 5 years. Positive AAPC describes an increasing trend and a negative AAPC a decreasing one.

Cancer in Context

How Does Cancer Compare to Other Causes of Death?

Cancer caused 21.8% of all deaths in the United States in 2016. Deaths due to heart disease and cancer caused nearly half of all deaths in the United States. Cancer is the leading cause of death for those under 65 years of age.

Leading Causes of Death in the U.S., 2016
Heart Disease 635,226
Cancer 598,031
Chronic Lower Respiratory 154,592
Accidents (Unintentional Injury) 161,346
Stroke (Cerebrovascular) 142,134
Alzheimer's 116,103
Diabetes 80,058
Pneumonia & Influenze 51,537
Nephritis & Nephrosis 50,042
Intentional Self-Harm (Suicide) 44,962

What Are the U.S. Death Rates?

In the United States, heart disease death rates have decreased for people of all ages. In 1975, heart disease among those less than 65 caused 26% of deaths, compared to 17% in 2016. In those over 65, heart disease caused 44% of deaths in 1975, compared to 25% in 2016.

Neoplasms have slightly increased for people of all ages. In 1975, neoplasms for those less than 65 accounted for 22% of deaths in the United States, compared to 24% in 2016. In those over 65, neoplasms caused 18% of deaths in 1975, compared to 21% in 2016.

Ages <65
Year Heart Disease Cancer
Rate Per 100,000 % of Total Deaths Rate Per 100,000 % of Total Deaths
1975 98.6 26 84.0 22
1976 95.9 26 84.3 23
1977 92.6 26 84.3 23
1978 90.4 26 84.2 24
1979 88.3 26 83.3 24
1980 86.9 26 83.7 24
1981 84.9 26 82.8 25
1982 82.0 26 83.0 26
1983 80.7 26 82.7 26
1984 78.3 25 83.3 26
1985 76.6 25 83.2 26
1986 74.0 24 82.2 26
1987 71.5 23 81.7 26
1988 69.1 22 81.3 26
1989 65.1 21 80.5 26
1990 62.4 21 80.1 26
1991 61.0 20 79.2 26
1992 59.7 20 77.4 26
1993 59.5 20 76.2 26
1994 57.8 20 75.0 26
1995 56.9 20 73.4 25
1996 55.5 20 71.7 26
1997 53.4 21 69.7 27
1998 51.4 20 67.9 27
1999 49.4 20 66.9 27
2000 47.7 19 65.5 27
2001 46.6 19 64.9 26
2002 46.3 19 63.7 26
2003 45.3 19 62.3 26
2004 43.1 19 60.4 26
2005 42.6 18 59.7 26
2006 41.5 18 58.5 26
2007 40.0 18 56.9 26
2008 39.5 18 55.8 26
2009 38.3 18 55.3 26
2010 37.4 18 54.2 27
2011 37.1 18 53.4 26
2012 36.9 18 53.0 26
2013 36.9 18 51.9 26
2014 37.0 18 51.5 25
2015 37.2 18 50.4 25
2016 37.4 17 49.6 24
Ages 65+
Year Heart Disease Cancer
Rate Per 100,000 % of Total Deaths Rate Per 100,000 % of Total Deaths
1975 2734.9 44 995.2 18
1976 2747.4 44 1018.3 18
1977 2656.3 44 1023.3 19
1978 2643.2 44 1035.4 19
1979 2595.8 45 1042.7 19
1980 2652.4 44 1059.1 19
1981 2568.9 44 1060.7 20
1982 2524.7 44 1074.6 20
1983 2532.4 44 1083.5 20
1984 2468.6 43 1093.0 20
1985 2449.2 42 1097.2 20
1986 2389.6 42 1107.5 21
1987 2333.4 41 1111.8 21
1988 2321.1 40 1120.3 21
1989 2184.9 39 1139.1 22
1990 2102.7 39 1147.4 22
1991 2054.6 38 1154.0 23
1992 1995.9 38 1153.7 23
1993 2027.9 37 1161.8 22
1994 1954.3 37 1157.0 23
1995 1927.5 36 1153.6 22
1996 1878.5 36 1142.2 22
1997 1828.4 35 1128.5 22
1998 1791.7 35 1119.6 22
1999 1766.3 34 1125.9 22
2000 1698.3 33 1119.8 22
2001 1648.2 32 1104.4 22
2002 1611.1 32 1097.2 22
2003 1551.7 31 1079.7 22
2004 1449.7 30 1060.8 22
2005 1415.4 30 1053.2 22
2006 1333.7 29 1036.1 22
2007 1268.7 28 1025.1 22
2008 1240.5 28 1009.5 22
2009 1174.6 27 989.8 22
2010 1143.5 27 984.0 22
2011 1113.8 26 965.9 22
2012 1088.5 26 950.0 22
2013 1085.3 26 932.2 21
2014 1063.0 25 920.3 22
2015 1075.3 25 907.0 21
2016 1050.9 25 890.3 21

More About Cancer Surveillance

More Information

Here are some resources for learning more about cancer surveillance:

References

All statistics in this report are based on statistics from SEER and the Centers for Disease Control and Prevention's National Center for Health Statistics. Most can be found within:

Howlader N, Noone AM, Krapcho M, Miller D, Brest A, Yu M, Ruhl J, Tatalovich Z, Mariotto A, Lewis DR, Chen HS, Feuer EJ, Cronin KA (eds). SEER Cancer Statistics Review, 1975-2016, National Cancer Institute. Bethesda, MD, https://seer.cancer.gov/csr/1975_2016/, based on November 2018 SEER data submission, posted to the SEER web site, April 2019.

Suggested Citation

All material in this report is in the public domain and may be reproduced or copied without permission; citation as to source, however, is appreciated.

SEER Cancer Statistics Factsheets: Common Cancer Sites. National Cancer Institute. Bethesda, MD, https://seer.cancer.gov/statfacts/html/common.html