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Statistics at a Glance

At a Glance

Estimated New Cases in 2025 2,041,910

% of All New Cancer Cases 100.0%

Estimated Deaths in 2025 618,120

% of All Cancer Deaths 100.0%

5-Year
Relative Survival

69.9% 2015–2021
Year Rate of New Cases — SEER 8 Rate of New Cases — SEER 12 Death Rate — U.S. 5-Year Relative Survival — SEER 8
Observed Modeled Trend Observed Modeled Trend Observed Modeled Trend Observed Modeled Trend
1975 400.02 400.40 - - 199.02 201.08 49.85% 50.00%
1976 405.13 402.67 - - 202.25 202.02 50.35% 50.30%
1977 404.70 404.95 - - 202.95 202.97 50.32% 50.59%
1978 403.84 407.25 - - 204.37 203.92 50.47% 50.89%
1979 409.53 409.56 - - 204.50 204.87 49.85% 51.19%
1980 412.06 411.88 - - 206.94 205.83 50.42% 51.49%
1981 416.94 414.21 - - 206.44 206.80 51.08% 51.78%
1982 414.62 416.56 - - 208.34 207.77 51.07% 52.08%
1983 421.98 423.71 - - 209.26 208.74 52.07% 52.37%
1984 432.00 430.98 - - 210.93 209.72 52.21% 52.66%
1985 441.88 438.37 - - 211.39 210.70 53.72% 53.81%
1986 444.61 445.90 - - 211.85 211.69 54.55% 54.95%
1987 461.10 453.55 - - 212.02 212.68 55.68% 56.07%
1988 457.76 461.33 - - 212.74 213.67 56.44% 57.17%
1989 460.21 469.25 - - 214.42 214.68 56.65% 58.26%
1990 473.95 477.31 - - 215.09 215.68 58.66% 59.33%
1991 492.40 485.50 - - 215.16 216.69 60.79% 60.38%
1992 499.91 493.83 494.93 493.23 213.61 214.59 62.33% 61.42%
1993 481.41 486.62 477.90 481.26 213.63 212.52 61.85% 61.74%
1994 473.07 479.51 466.97 469.57 211.88 210.46 61.72% 62.06%
1995 467.57 472.50 464.08 469.34 210.00 208.42 62.17% 62.38%
1996 471.06 473.31 466.54 469.11 207.10 206.41 63.38% 63.06%
1997 476.75 474.12 470.85 468.87 203.63 204.41 64.15% 63.73%
1998 477.02 474.92 471.31 468.64 200.89 202.43 64.74% 64.40%
1999 480.88 475.74 473.50 468.41 200.78 200.47 65.89% 65.05%
2000 476.28 476.55 466.79 468.18 198.86 198.53 66.65% 65.70%
2001 486.86 477.36 477.00 467.94 196.36 196.61 67.57% 66.33%
2002 484.76 478.17 472.39 467.71 194.44 193.70 67.95% 66.96%
2003 474.76 478.99 463.44 467.48 190.97 190.84 67.39% 67.58%
2004 477.89 479.81 466.58 467.25 186.93 188.01 68.24% 68.19%
2005 475.42 480.63 463.44 467.02 185.32 185.23 68.76% 68.79%
2006 479.97 481.45 464.72 466.78 182.12 182.49 69.60% 69.39%
2007 484.39 482.27 471.03 466.55 179.34 179.79 70.06% 69.97%
2008 478.98 483.09 465.42 466.32 176.40 177.12 70.05% 69.99%
2009 478.41 476.09 464.56 466.09 173.46 174.50 70.44% 70.01%
2010 468.95 469.19 455.40 457.24 171.93 171.92 70.32% 70.03%
2011 463.40 462.40 448.29 448.57 169.35 169.38 70.44% 70.04%
2012 453.55 455.70 437.97 440.05 167.36 166.87 69.82% 70.06%
2013 448.50 449.09 432.58 431.70 164.63 164.40 70.42% 70.55%
2014 448.37 449.60 430.66 432.06 163.13 161.97 70.65% 71.02%
2015 450.78 450.11 432.40 432.41 160.94 159.57 71.61% 71.50%
2016 451.76 450.61 433.19 432.77 158.42 157.21 71.88% 71.96%
2017 451.82 451.12 433.67 433.13 155.42 154.88 72.55% 72.42%
2018 448.12 451.63 431.55 433.48 152.27 152.59 - 72.88%
2019 456.50 452.14 439.43 433.84 149.38 150.33 - 73.33%
2020 411.63 452.65 396.80 434.20 147.32 148.10 - 73.77%
2021 459.01 453.16 440.08 434.55 145.83 145.91 - 74.20%
2022 446.87 453.67 427.18 434.91 143.60 143.75 - 74.63%
2023 - - - - 141.39 141.62 - -

New cases come from SEER 12. Deaths come from U.S. Mortality.
All Races, Both Sexes. Rates are Age-Adjusted.
Modeled trend lines were calculated from the underlying rates using the Joinpoint Trend Analysis Software.
The 2020 incidence rate is displayed but not used in the fit of the trend line(s). Impact of COVID on SEER Cancer Incidence 2020 data

New cases are also referred to as incident cases in other publications. Rates of new cases are also referred to as incidence rates.

Rate of New Cases and Deaths per 100,000: The rate of new cases of cancer of any site was 445.8 per 100,000 men and women per year. The death rate was 145.4 per 100,000 men and women per year. These rates are age-adjusted and based on 2018–2022 cases and 2019–2023 deaths.

Lifetime Risk of Developing Cancer: Approximately 38.9 percent of men and women will be diagnosed with cancer of any site at some point during their lifetime, based on 2018–2021 data, excluding 2020 due to COVID.

Prevalence of This Cancer: In 2022, there were an estimated 18,000,110 people living with cancer of any site in the United States.

Did You Know? Video Series

Survival Statistics

How Many People Survive 5 Years Or More after Being Diagnosed with Cancer of Any Site?

Relative survival is an estimate of the percentage of patients who would be expected to survive the effects of their cancer. It excludes the risk of dying from other causes. Because survival statistics are based on large groups of people, they cannot be used to predict exactly what will happen to an individual patient. No two patients are entirely alike, and treatment and responses to treatment can vary greatly.

69.9%

5-Year
Relative Survival

69.9%

Based on data from SEER 21 (Excluding IL) 2015–2021. Gray figures represent those who have died from cancer of any site. Green figures represent those who have survived 5 years or more.

Additional Information

New Cases and Deaths

How Common Is This Cancer?

Common Types of Cancer Estimated New
Cases 2025		 Estimated
Deaths 2025
1. Breast Cancer (Female) 316,950 42,170
2. Prostate Cancer 313,780 35,770
3. Lung and Bronchus Cancer 226,650 124,730
4. Colorectal Cancer 154,270 52,900
5. Melanoma of the Skin 104,960 8,430
6. Bladder Cancer 84,870 17,420
7. Kidney and Renal Pelvis Cancer 80,980 14,510
8. Non-Hodgkin Lymphoma 80,350 19,390
9. Uterine Cancer 69,120 13,860
10. Pancreatic Cancer 67,440 51,980
- - -
Cancer of Any Site 2,041,910 618,120

In 2025, it is estimated that there will be 2,041,910 new cases of cancer of any site and an estimated 618,120 people will die of this disease.

Who Gets This Cancer?

Among racial/ethnic groups, there are more new cases among non-Hispanic Black men and non-Hispanic White women and fewer new cases among non-Hispanic Asian/Pacific Islanders of both sexes. The rate of new cases of cancer of any site was 445.8 per 100,000 men and women per year based on 2018–2022 cases, age-adjusted.

Rate of New Cases per 100,000 Persons by Race/Ethnicity & Sex: Cancer of Any Site
Males
All Races 483.5
Hispanic 372.3
Non-Hispanic American Indian/Alaska Native 449.2
Non-Hispanic Asian/Pacific Islander 305.0
Non-Hispanic Black 533.0
Non-Hispanic White 517.6
Females
All Races 421.3
Hispanic 357.6
Non-Hispanic American Indian/Alaska Native 431.8
Non-Hispanic Asian/Pacific Islander 321.4
Non-Hispanic Black 408.0
Non-Hispanic White 451.1

SEER 21 2018–2022, Age-Adjusted

Percent of New Cases by Age Group: Cancer of Any Site
Age Range Percent of New Cases
<20 0.9%
20–34 2.7%
35–44 4.8%
45–54 10.8%
55–64 23.4%
65–74 30.5%
75–84 19.4%
>84 7.4%

Cancer of any site is most frequently diagnosed among people aged 65–74.

Median Age
At Diagnosis

67

SEER 21 2018–2022, All Races, Both Sexes

Who Dies From This Cancer?

Death rates for cancer are higher among the middle-aged and elderly populations. The death rate was 145.4 per 100,000 men and women per year based on 2019–2023 deaths, age-adjusted.

Death Rate per 100,000 Persons by Race/Ethnicity & Sex: Cancer of Any Site
Males
All Races 171.5
Hispanic 124.4
Non-Hispanic American Indian/Alaska Native 180.5
Non-Hispanic Asian/Pacific Islander 107.1
Non-Hispanic Black 203.6
Non-Hispanic White 178.0
Females
All Races 126.3
Hispanic 93.2
Non-Hispanic American Indian/Alaska Native 141.2
Non-Hispanic Asian/Pacific Islander 83.1
Non-Hispanic Black 143.7
Non-Hispanic White 131.2

U.S. 2019–2023, Age-Adjusted

Percent of Deaths by Age Group: Cancer of Any Site
Age Range Percent of Deaths
<20 0.3%
20–34 0.7%
35–44 1.8%
45–54 5.6%
55–64 17.7%
65–74 29.2%
75–84 27.7%
>84 17.0%

The percent of cancer of any site deaths is highest among people aged 65–74.

Median Age
At Death

73

U.S. 2019–2023, All Races, Both Sexes

Trends in Rates

Changes Over Time

Keeping track of new cases, deaths, and survival over time (trends) can help scientists understand whether progress is being made and where additional research is needed to address challenges, such as improving screening or finding better treatments.

Using statistical models for analysis, age-adjusted rates for new cancer of any site cases have been stable over 2013–2022. Age-adjusted death rates have been falling on average 1.5% each year over 2014–2023. 5-year relative survival trends are shown below.

New Cases, Deaths and 5-Year Relative Survival

Interactive Statistics with SEER*Explorer

With SEER*Explorer, you can...
  • Create custom graphs and tables
  • Download data and images
  • Share links to results

SEER*Explorer is an interactive website that provides easy access to a wide range of SEER cancer statistics. It provides detailed statistics for a cancer site by sex, race, calendar year, age, and for a selected number of cancer sites, by stage and histology.

Explore Additional Cancer of Any Site Statistics

More About This Cancer

More Information

Here are some resources for learning more about cancer.

References

All statistics in this report are based on statistics from SEER and the Centers for Disease Control and Prevention's National Center for Health Statistics. Most can be found within SEER*Explorer.

Suggested Citation

All material in this report is in the public domain and may be reproduced or copied without permission; citation as to source, however, is appreciated.

SEER Cancer Stat Facts: Cancer of Any Site. National Cancer Institute. Bethesda, MD, https://seer.cancer.gov/statfacts/html/all.html

These stat facts focus on population statistics that are based on the U.S. population. Because these statistics are based on large groups of people, they cannot be used to predict exactly what will happen to an individual patient. To see tailored statistics, browse SEER*Explorer. To see statistics for a specific state, go to the State Cancer Profiles.

The statistics presented in these stat facts are based on the most recent data available, most of which can be found in SEER*Explorer. In some cases, different year spans may be used.

Estimates of new cases and deaths for 2025 are projections made by the American Cancer Society (ACS), based on earlier reported data.

Cancer is a complex topic. There is a wide range of information available. These stat facts do not address causes, symptoms, diagnosis, treatment, follow-up care, or decision making, although links are provided to information in many of these areas.