Statistics at a Glance

At a Glance

Year New Cases - SEER 9 New Cases - SEER 13 Deaths - U.S. Percent Surviving 5 Years - SEER 9
Observed Modeled Trend Observed Modeled Trend Observed Modeled Trend Observed Modeled Trend
1975 2.13 2.46 - - 0.93 0.90 63.06% 57.51%
1976 2.24 2.45 - - 0.91 0.89 60.17% 58.21%
1977 2.90 2.44 - - 0.92 0.88 55.43% 58.91%
1978 2.47 2.42 - - 0.80 0.87 54.80% 59.60%
1979 2.53 2.41 - - 0.86 0.86 60.15% 60.28%
1980 2.49 2.40 - - 0.83 0.85 59.26% 60.95%
1981 2.35 2.39 - - 0.82 0.84 58.31% 61.62%
1982 2.30 2.37 - - 0.91 0.83 55.58% 62.28%
1983 2.21 2.36 - - 0.82 0.83 61.77% 62.93%
1984 2.56 2.55 - - 0.79 0.82 66.63% 63.57%
1985 2.70 2.75 - - 0.79 0.81 62.68% 64.21%
1986 3.25 2.97 - - 0.81 0.80 62.95% 64.83%
1987 2.94 2.98 - - 0.71 0.79 71.91% 65.45%
1988 3.04 2.99 - - 0.80 0.78 63.69% 66.07%
1989 3.02 3.00 - - 0.80 0.78 62.75% 66.67%
1990 3.16 3.01 - - 0.79 0.77 64.37% 67.27%
1991 3.06 3.02 - - 0.80 0.76 68.65% 67.85%
1992 3.26 3.03 3.13 2.82 0.74 0.75 66.55% 68.43%
1993 2.96 3.04 2.84 2.84 0.77 0.74 66.81% 69.01%
1994 2.93 3.05 2.77 2.85 0.73 0.74 75.20% 69.57%
1995 3.04 3.06 2.77 2.86 0.68 0.73 72.54% 70.13%
1996 3.01 3.07 2.84 2.87 0.74 0.72 76.45% 70.68%
1997 2.63 3.08 2.64 2.88 0.69 0.71 75.31% 71.22%
1998 2.79 3.09 2.76 2.89 0.68 0.71 76.71% 71.75%
1999 3.02 3.10 2.85 2.91 0.68 0.70 73.11% 72.27%
2000 3.17 3.11 2.85 2.92 0.68 0.69 73.06% 72.79%
2001 3.46 3.12 3.17 2.93 0.64 0.69 77.51% 73.30%
2002 3.44 3.13 3.13 2.94 0.71 0.68 75.53% 73.80%
2003 2.91 3.14 2.94 2.95 0.71 0.67 78.00% 74.30%
2004 3.01 3.15 2.99 2.96 0.68 0.66 73.19% 74.78%
2005 3.04 3.16 2.98 2.98 0.67 0.66 76.05% 75.26%
2006 2.81 3.17 2.78 2.99 0.64 0.65 77.90% 75.73%
2007 3.06 3.18 2.98 3.00 0.64 0.64 72.71% 76.20%
2008 3.25 3.19 2.99 3.01 0.65 0.64 75.38% 76.65%
2009 3.33 3.20 3.21 3.02 0.63 0.63 76.17% 77.10%
2010 3.62 3.21 3.31 3.04 0.60 0.64 71.25% 77.54%
2011 3.19 3.23 2.89 3.05 0.67 0.65 - 77.98%
2012 2.89 3.24 2.70 3.06 0.70 0.66 - 78.40%
2013 3.35 3.25 3.14 3.07 0.68 0.67 - 78.82%
2014 3.25 3.26 3.11 3.09 0.68 0.68 - 79.24%
2015 3.51 3.27 3.19 3.10 0.65 0.68 - 79.64%

Modeled trend lines were calculated from the underlying rates using the Joinpoint Trend Analysis Software.


Percent Surviving
5 Years

74.2% 2008-2014

Number of New Cases and Deaths per 100,000: The number of new cases of childhood brain and other nervous system cancer was 3.1 per 100,000 children per year. The number of deaths was 0.7 per 100,000 children per year. These rates are age-adjusted and based on 2011-2015 cases and deaths.

Did You Know? Video Series

Survival Statistics

How Many People Survive 5 Years Or More after Being Diagnosed with Childhood Brain and Other Nervous System Cancer?

Relative survival statistics compare the survival of patients diagnosed with cancer with the survival of people in the general population who are the same age, race, and sex and who have not been diagnosed with cancer. Because survival statistics are based on large groups of people, they cannot be used to predict exactly what will happen to an individual patient. No two patients are entirely alike, and treatment and responses to treatment can vary greatly.

74.2%

Percent Surviving
5 Years

74.2%

Based on data from SEER 18 2008-2014. Gray figures represent those who have died from childhood brain and other nervous system cancer. Green figures represent those who have survived 5 years or more.

Additional Information

Survival by Stage

Cancer stage at diagnosis, which refers to extent of a cancer in the body, determines treatment options and has a strong influence on the length of survival. In general, if the cancer is found only in the part of the body where it started it is localized (sometimes referred to as stage 1). If it has spread to a different part of the body, the stage is regional or distant. The earlier childhood brain and other nervous system cancer is caught, the better chance a person has of surviving five years after being diagnosed. For childhood brain and other nervous system cancer, 79.7% are diagnosed at the local stage. The 5-year survival for localized childhood brain and other nervous system cancer is 77.2%.

Percent of Cases & 5-Year Relative Survival by Stage at Diagnosis: Childhood Brain and Other Nervous System Cancer
Stage Percent of Cases 5-Year Relative Survival
Localized
Confined to Primary Site
80% 77.2%
Regional
Spread to Regional Lymph Nodes
10% 63.1%
Distant
Cancer has Metastasized
6% 53.4%
Unknown
Unstaged
3% 79.9%

SEER 18 2008-2014, All Races, Both Sexes by SEER Summary Stage 2000

Additional Information

Number of New Cases and Deaths

How Common Is This Cancer?

Compared to other childhood cancers, childhood brain and other nervous system cancer is fairly common.

Rank Common Types of Childhood Cancer New Cases
Per 100,000
Deaths
Per 100,000
1. Leukemia 4.7 0.6
2. Brain and Other Nervous System 3.1 0.7
3. Non-Hodgkin Lymphoma 1.3 0.1
4. Hodgkin Lymphoma 1.2 0.0
5. Testis 1.2 0.0
6. Soft Tissue including Heart 1.1 0.2
7. Thyroid 1.1 0.0
8. Bone and Joint 1.0 0.2
9. Kidney and Renal Pelvis 0.7 0.1
10. Ovary 0.7 0.0

Childhood brain and other nervous system cancer represents 17.2% of all new childhood cancer cases.

17.2%

SEER 18 Incidence & U.S. Mortality 2011-2015, Ages 0-19. Rates are Age-Adjusted

Who Gets This Cancer?

Childhood brain and other nervous system cancer is slightly more common in boys than girls. The number of new cases of childhood brain and other nervous system cancer was 3.1 per 100,000 children per year based on 2011-2015 cases.

Number of New Cases per 100,000 Persons by Race/Ethnicity & Sex: Childhood Brain and Other Nervous System Cancer (Ages 0-19)
Males
All Races 3.3
White 3.5
Black 2.5
Asian/Pacific Islander 2.6
American Indian/Alaska Native Not Shown, <16 cases
Hispanic 2.5
Non-Hispanic 3.6
Females
All Races 3.0
White 3.2
Black 2.6
Asian/Pacific Islander 2.0
American Indian/Alaska Native Not Shown, <16 cases
Hispanic 2.2
Non-Hispanic 3.3

SEER 18 2011-2015, Age-Adjusted

Percent of New Cases by Age Group: Childhood Brain and Other Nervous System Cancer
Age Range Percent of New Cases
<1 5.6%
1-4 26.0%
5-9 27.4%
10-14 21.2%
15-19 19.8%

Childhood brain and other nervous system cancer is most frequently diagnosed among children aged 5-9.

Median Age
At Diagnosis

8

SEER 18 2011-2015, All Races, Both Sexes

Who Dies From This Cancer?

Brain and other nervous system cancer is the leading cause of childhood cancer death in the United States. The number of deaths was 0.7 per 100,000 children per year based on 2011-2015 deaths.

Number of Deaths per 100,000 Persons by Race/Ethnicity & Sex: Childhood Brain and Other Nervous System Cancer (Ages 0-19)
Males
All Races 0.7
White 0.8
Black 0.7
Asian/Pacific Islander 0.7
American Indian/Alaska Native 0.9
Hispanic 0.6
Non-Hispanic 0.8
Females
All Races 0.6
White 0.6
Black 0.6
Asian/Pacific Islander 0.4
American Indian/Alaska Native Not Shown, <16 cases
Hispanic 0.6
Non-Hispanic 0.6

U.S. 2011-2015, Age-Adjusted

Percent of Deaths by Age Group: Childhood Brain and Other Nervous System Cancer
Age Range Percent of Deaths
<1 2.6%
1-4 17.8%
5-9 34.5%
10-14 24.0%
15-19 21.2%

The percent of childhood brain and other nervous system cancer deaths is highest among children aged 5-9.

Median Age
At Death

9

U.S. 2011-2015, All Races, Both Sexes

Trends in Rates

Changes Over Time

Keeping track of the number of new cases, deaths, and survival over time (trends) can help scientists understand whether progress is being made and where additional research is needed to address challenges, such as improving screening or finding better treatments.

Using statistical models for analysis, rates for new childhood brain and other nervous system cancer cases have been stable over the last 10 years. Death rates have not changed significantly over 2006-2015. 5-year survival trends are shown below.

More About This Cancer

Cancer and the Brain

Figure: Brain Anatomy

Figure: Drawing of brain anatomy showing the brain stem, pons, medulla, spinal cord, cerebellum, cerebrum, meninges, ventricles (fluid-filled spaces), and skull.

Figure: Brain Anatomy

Figure: Drawing of brain anatomy showing the supratentorial area (the upper part of the brain) and the posterior fossa/infratentorial area (the lower back part of the brain). The supratentorial area contains the cerebrum, lateral ventricle, third ventricle, choroid plexus, hypothalamus, pineal gland, pituitary gland, and optic nerve. The posterior fossa/infratentorial area contains the cerebellum, tectum, fourth ventricle, and brain stem (pons and medulla). The tentorium and spinal cord are also shown.

Brain and other nervous system cancer is the second most common type of childhood cancer. Although there are many types of brain and other nervous system cancer in children, malignant pilocytic astrocytomas, medulloblastomas, and malignant gliomas make up the majority of all cases. This factsheet combines all types of childhood brain and other nervous system cancer.

Even when diagnosed with the same type of brain or nervous system tumor, symptoms and outcomes for children differ from adults.

Brain and other central nervous system cancer develops when abnormal cells form in the tissues of the brain and spinal cord. Abnormal cell growth forms tumors, which may be benign (not cancer) or malignant (cancer). Both benign and malignant brain tumors need treatment. There are many types of childhood brain and other nervous system cancer, including:

Childhood brain and other nervous system cancer is described as untreated, in remission, or recurrent.

Additional Information

More Information

Here are some resources for learning more about brain and other nervous system cancers.

References

All statistics in this report are based on statistics from SEER and the Centers for Disease Control and Prevention's National Center for Health Statistics. Most can be found within:

Noone AM, Howlader N, Krapcho M, Miller D, Brest A, Yu M, Ruhl J, Tatalovich Z, Mariotto A, Lewis DR, Chen HS, Feuer EJ, Cronin KA (eds). SEER Cancer Statistics Review, 1975-2015, National Cancer Institute. Bethesda, MD, https://seer.cancer.gov/csr/1975_2015/, based on November 2017 SEER data submission, posted to the SEER web site, April 2018.

Suggested Citation

All material in this report is in the public domain and may be reproduced or copied without permission; citation as to source, however, is appreciated.

SEER Cancer Stat Facts: Childhood Brain and Other Nervous System Cancer. National Cancer Institute. Bethesda, MD, https://seer.cancer.gov/statfacts/html/childbrain.html

These stat facts focus on population statistics that are based on the U.S. population. Because these statistics are based on large groups of people, they cannot be used to predict exactly what will happen to an individual patient. To see tailored statistics, browse the SEER Cancer Statistics Review. To see statistics for a specific state, go to the State Cancer Profiles.

The statistics presented in these stat facts are based on the most recent data available, most of which can be found in the SEER Cancer Statistics Review. In some cases, different year spans may be used. Estimates for the current year are based on past data.

Cancer is a complex topic. There is a wide range of information available. These stat facts do not address causes, symptoms, diagnosis, treatment, follow-up care, or decision making, although links are provided to information in many of these areas.