Statistics at a Glance
At a Glance
Estimated New Cases in 2020 21,040
% of All New Cancer Cases 1.2%
Estimated Deaths in 2020 4,060
% of All Cancer Deaths 0.7%
|Year||Rate of New Cases — SEER 9||Rate of New Cases — SEER 13||Death Rate — U.S.||5-Year Relative Survival — SEER 9|
|Observed||Modeled Trend||Observed||Modeled Trend||Observed||Modeled Trend||Observed||Modeled Trend|
New cases come from SEER 13. Deaths come from U.S. Mortality.
All Races, Both Sexes. Rates are Age-Adjusted.
Modeled trend lines were calculated from the underlying rates using the Joinpoint Trend Analysis Software.
New cases are also referred to as incident cases in other publications. Rates of new cases are also referred to as incidence rates.
Rate of New Cases and Deaths per 100,000: The rate of new cases of chronic lymphocytic leukemia was 5.0 per 100,000 men and women per year. The death rate was 1.2 per 100,000 men and women per year. These rates are age-adjusted and based on 2013–2017 cases and deaths.
Lifetime Risk of Developing Cancer: Approximately 0.6 percent of men and women will be diagnosed with chronic lymphocytic leukemia at some point during their lifetime, based on 2015–2017 data.
Prevalence of This Cancer: In 2017, there were an estimated 186,422 people living with chronic lymphocytic leukemia in the United States.
How Many People Survive 5 Years Or More after Being Diagnosed with Chronic Lymphocytic Leukemia?
Relative survival statistics compare the survival of patients diagnosed with cancer with the survival of people in the general population who are the same age, race, and sex and who have not been diagnosed with cancer. Because survival statistics are based on large groups of people, they cannot be used to predict exactly what will happen to an individual patient. No two patients are entirely alike, and treatment and responses to treatment can vary greatly.
Based on data from SEER 18 2010–2016. Gray figures represent those who have died from chronic lymphocytic leukemia. Green figures represent those who have survived 5 years or more.
New Cases and Deaths
How Common Is This Cancer?
|Rank||Common Types of Cancer||Estimated New
|1.||Breast Cancer (Female)||276,480||42,170|
|2.||Lung and Bronchus Cancer||228,820||135,720|
|5.||Melanoma of the Skin||100,350||6,850|
|8.||Kidney and Renal Pelvis Cancer||73,750||14,830|
|Chronic Lymphocytic Leukemia||21,040||4,060|
Chronic lymphocytic leukemia represents 1.2% of all new cancer cases in the U.S.
In 2020, it is estimated that there will be 21,040 new cases of chronic lymphocytic leukemia and an estimated 4,060 people will die of this disease.
Who Gets This Cancer?
Chronic lymphocytic leukemia is more common in adults and more common among men than women, particularly white men. The rate of new cases of chronic lymphocytic leukemia was 5.0 per 100,000 men and women per year based on 2013–2017 cases, age-adjusted.
|American Indian/Alaska Native||2.8|
|American Indian/Alaska Native||0.9|
SEER 21 2013–2017, Age-Adjusted
|Age Range||Percent of New Cases|
Chronic lymphocytic leukemia is most frequently diagnosed among people aged 65–74.
SEER 21 2013–2017, All Races, Both Sexes
Who Dies From This Cancer?
Death rates from chronic lymphocytic leukemia are higher among older adults, or those 75 and older. People with leukemia have many treatment options, and treatment for leukemia can often control the disease and its symptoms. The death rate was 1.2 per 100,000 men and women per year based on 2013–2017 deaths, age-adjusted.
|American Indian/Alaska Native||0.5|
|American Indian/Alaska Native||Not Shown, <16 cases|
U.S. 2013–2017, Age-Adjusted
|Age Range||Percent of Deaths|
The percent of chronic lymphocytic leukemia deaths is highest among people aged 85+.
U.S. 2013–2017, All Races, Both Sexes
Trends in Rates
Changes Over Time
Keeping track of new cases, deaths, and survival over time (trends) can help scientists understand whether progress is being made and where additional research is needed to address challenges, such as improving screening or finding better treatments.
Using statistical models for analysis, age-adjusted rates for new chronic lymphocytic leukemia cases have been falling on average 1.4% each year over the last 10 years. Age-adjusted death rates have been falling on average 2.9% each year over 2008–2017. 5-year relative survival trends are shown below.
More About This Cancer
Cancer and the Blood
Figure: Stem cells maturing into one of three types of mature blood cells: red blood cells, platelets, and white blood cells. Precursor cells are also shown: stem cells, myeloid blasts, lymphoid stem cells, and lymphoid blasts.
Leukemia is cancer that starts in the tissue that forms blood. Most blood cells develop from cells in the bone marrow called stem cells. In a person with leukemia, the bone marrow makes abnormal white blood cells. The abnormal cells are leukemia cells. Unlike normal blood cells, leukemia cells don't die when they should. They may crowd out normal white blood cells, red blood cells, and platelets. This makes it hard for normal blood cells to do their work. The four main types of leukemia are:
- Acute lymphoblastic leukemia (ALL)
- Acute myelogenous leukemia (AML)
- Chronic lymphocytic leukemia (CLL)
- Chronic myelogenous leukemia (CML)
Here are some resources for learning more about leukemia.
All statistics in this report are based on statistics from SEER and the Centers for Disease Control and Prevention's National Center for Health Statistics. Most can be found within:
Howlader N, Noone AM, Krapcho M, Miller D, Brest A, Yu M, Ruhl J, Tatalovich Z, Mariotto A, Lewis DR, Chen HS, Feuer EJ, Cronin KA (eds). SEER Cancer Statistics Review, 1975–2017, National Cancer Institute. Bethesda, MD, https://seer.cancer.gov/csr/1975_2017/, based on November 2019 SEER data submission, posted to the SEER web site, April 2020.
All material in this report is in the public domain and may be reproduced or copied without permission; citation as to source, however, is appreciated.
SEER Cancer Stat Facts: Chronic Lymphocytic Leukemia. National Cancer Institute. Bethesda, MD, https://seer.cancer.gov/statfacts/html/clyl.html
These stat facts focus on population statistics that are based on the U.S. population. Because these statistics are based on large groups of people, they cannot be used to predict exactly what will happen to an individual patient. To see tailored statistics, browse the SEER Cancer Statistics Review. To see statistics for a specific state, go to the State Cancer Profiles.
The statistics presented in these stat facts are based on the most recent data available, most of which can be found in the SEER Cancer Statistics Review. In some cases, different year spans may be used. Estimates for the current year are based on past data.
Cancer is a complex topic. There is a wide range of information available. These stat facts do not address causes, symptoms, diagnosis, treatment, follow-up care, or decision making, although links are provided to information in many of these areas.