Statistics at a Glance

At a Glance

Estimated New Cases in 2021 66,570

% of All New Cancer Cases 3.5%

Estimated Deaths in 2021 12,940

% of All Cancer Deaths 2.1%

5-Year
Relative Survival

81.1% 2011–2017
Year Rate of New Cases — SEER 9 Rate of New Cases — SEER 13 Death Rate — U.S. 5-Year Relative Survival — SEER 9
Observed Modeled Trend Observed Modeled Trend Observed Modeled Trend Observed Modeled Trend
1975 35.49 35.93 - - 5.28 5.39 87.99% 88.22%
1976 34.37 33.79 - - 5.33 5.30 87.55% 86.99%
1977 31.67 31.77 - - 5.22 5.22 85.60% 85.65%
1978 30.05 29.87 - - 5.10 5.13 84.46% 84.18%
1979 27.91 28.09 - - 4.99 5.05 83.51% 82.57%
1980 27.32 27.61 - - 5.12 4.97 79.83% 80.82%
1981 27.27 27.13 - - 4.88 4.89 80.75% 81.02%
1982 26.78 26.67 - - 4.85 4.81 80.99% 81.22%
1983 26.51 26.21 - - 4.80 4.73 81.01% 81.41%
1984 25.69 25.76 - - 4.68 4.66 82.78% 81.61%
1985 25.23 25.32 - - 4.61 4.58 83.02% 81.80%
1986 24.38 24.89 - - 4.44 4.51 82.16% 81.99%
1987 24.71 24.46 - - 4.42 4.44 81.58% 82.18%
1988 23.59 24.04 - - 4.35 4.37 82.38% 82.36%
1989 24.43 24.21 - - 4.26 4.30 83.33% 82.55%
1990 25.03 24.38 - - 4.34 4.27 82.68% 82.73%
1991 24.63 24.54 - - 4.18 4.24 83.30% 82.91%
1992 24.78 24.71 24.41 24.71 4.21 4.21 85.41% 83.09%
1993 24.30 24.88 23.89 24.65 4.17 4.18 83.24% 83.27%
1994 25.11 25.05 24.31 24.59 4.15 4.15 82.39% 83.45%
1995 25.34 25.22 24.88 24.54 4.15 4.13 84.35% 83.62%
1996 24.93 25.40 24.50 24.48 4.13 4.10 83.41% 83.79%
1997 25.89 25.57 25.29 24.43 4.00 4.07 84.17% 83.97%
1998 25.75 25.45 24.93 24.37 4.10 4.08 83.43% 84.14%
1999 25.34 25.33 24.63 24.32 4.08 4.10 84.43% 84.30%
2000 24.81 25.21 23.85 24.27 4.11 4.11 85.40% 84.23%
2001 25.30 25.09 24.76 24.21 4.18 4.12 83.31% 84.16%
2002 24.95 24.97 24.00 24.16 4.17 4.13 82.97% 84.09%
2003 24.38 24.85 23.61 24.10 4.14 4.15 83.58% 84.02%
2004 24.99 24.73 23.96 24.05 4.14 4.16 83.04% 83.94%
2005 24.88 24.61 24.06 24.00 4.12 4.17 83.49% 83.87%
2006 24.50 24.50 23.99 23.94 4.23 4.19 85.32% 83.80%
2007 25.21 25.32 24.43 24.71 4.20 4.20 84.23% 83.72%
2008 26.01 26.18 25.25 25.50 4.21 4.21 83.33% 83.65%
2009 27.29 27.06 26.45 26.31 4.17 4.29 83.49% 83.58%
2010 27.42 27.19 26.72 26.50 4.45 4.38 83.56% 83.50%
2011 27.20 27.32 26.65 26.68 4.48 4.46 82.68% 83.43%
2012 27.54 27.45 27.11 26.87 4.52 4.55 83.22% 83.35%
2013 27.03 27.58 26.65 27.05 4.65 4.63 82.49% 83.28%
2014 27.77 27.71 27.23 27.24 4.73 4.72 - 83.20%
2015 27.64 27.85 27.11 27.43 4.80 4.82 - 83.13%
2016 28.19 27.98 27.94 27.62 5.01 4.91 - 83.05%
2017 28.64 28.11 28.23 27.81 5.02 5.00 - 82.97%
2018 27.94 28.25 27.69 28.01 5.01 5.10 - 82.90%

New cases come from SEER 13. Deaths come from U.S. Mortality.
All Races, Females. Rates are Age-Adjusted.
Modeled trend lines were calculated from the underlying rates using the Joinpoint Trend Analysis Software.

New cases are also referred to as incident cases in other publications. Rates of new cases are also referred to as incidence rates.


Rate of New Cases and Deaths per 100,000: The rate of new cases of uterine cancer was 28.1 per 100,000 women per year. The death rate was 4.9 per 100,000 women per year. These rates are age-adjusted and based on 2014–2018 cases and deaths.

Lifetime Risk of Developing Cancer: Approximately 3.1 percent of women will be diagnosed with uterine cancer at some point during their lifetime, based on 2016–2018 data.

Prevalence of This Cancer: In 2018, there were an estimated 813,861 women living with uterine cancer in the United States.

Did You Know? Video Series

Survival Statistics

How Many People Survive 5 Years Or More after Being Diagnosed with Uterine Cancer?

Relative survival is an estimate of the percentage of patients who would be expected to survive the effects of their cancer. It excludes the risk of dying from other causes. Because survival statistics are based on large groups of people, they cannot be used to predict exactly what will happen to an individual patient. No two patients are entirely alike, and treatment and responses to treatment can vary greatly.

81.1%

5-Year
Relative Survival

81.1%

Based on data from SEER 18 2011–2017. Gray figures represent those who have died from uterine cancer. Green figures represent those who have survived 5 years or more.

Survival by Stage

Cancer stage at diagnosis, which refers to extent of a cancer in the body, determines treatment options and has a strong influence on the length of survival. In general, if the cancer is found only in the part of the body where it started it is localized (sometimes referred to as stage 1). If it has spread to a different part of the body, the stage is regional or distant. The earlier uterine cancer is caught, the better chance a person has of surviving five years after being diagnosed. For uterine cancer, 67.4% are diagnosed at the local stage. The 5-year relative survival for localized uterine cancer is 94.9%.

Percent of Cases & 5-Year Relative Survival by Stage at Diagnosis: Uterine Cancer
Stage Percent of Cases 5-Year Relative Survival
Localized
Confined to Primary Site
67% 94.9%
Regional
Spread to Regional Lymph Nodes
20% 69.3%
Distant
Cancer Has Metastasized
9% 17.8%
Unknown
Unstaged
4% 51.8%

SEER 18 2011–2017, All Races, Females by SEER Summary Stage 2000

New Cases and Deaths

How Common Is This Cancer?

Compared to other cancers, uterine cancer is fairly common.

Rank Common Types of Cancer Estimated New
Cases 2021
Estimated
Deaths 2021
1. Breast Cancer (Female) 281,550 43,600
2. Prostate Cancer 248,530 34,130
3. Lung and Bronchus Cancer 235,760 131,880
4. Colorectal Cancer 149,500 52,980
5. Melanoma of the Skin 106,110 7,180
6. Bladder Cancer 83,730 17,200
7. Non-Hodgkin Lymphoma 81,560 20,720
8. Kidney and Renal Pelvis Cancer 76,080 13,780
9. Uterine Cancer 66,570 12,940
10. Leukemia 61,090 23,660

Uterine cancer represents 3.5% of all new cancer cases in the U.S.

3.5%

In 2021, it is estimated that there will be 66,570 new cases of uterine cancer and an estimated 12,940 people will die of this disease.

Who Gets This Cancer?

Most cases of endometrial cancer are diagnosed in women aged 45–74. The rate of new cases of uterine cancer was 28.1 per 100,000 women per year based on 2014–2018 cases, age-adjusted.

Rate of New Cases per 100,000 Persons by Race/Ethnicity: Uterine Cancer
Males
All Races Sex-specific cancer type
White
Black
Asian/Pacific Islander
American Indian/Alaska Native
Hispanic
Non-Hispanic
Females
All Races 28.1
White 28.6
Black 28.5
Asian/Pacific Islander 22.3
American Indian/Alaska Native 20.0
Hispanic 25.3
Non-Hispanic 28.5

SEER 21 2014–2018, Age-Adjusted

Percent of New Cases by Age Group: Uterine Cancer
Age Range Percent of New Cases
<20 0.0%
20–34 1.5%
35–44 4.9%
45–54 14.9%
55–64 33.5%
65–74 29.4%
75–84 11.9%
>84 3.8%

Uterine cancer is most frequently diagnosed among women aged 55–64.

Median Age
At Diagnosis

63

SEER 21 2014–2018, All Races, Females

Who Dies From This Cancer?

Most deaths from endometrial cancer occur in women who are middle-aged or older. Uterine cancer is the fourteenth leading cause of cancer death in the United States. The death rate was 4.9 per 100,000 women per year based on 2014–2018, age-adjusted.

Death Rate per 100,000 Persons by Race/Ethnicity: Uterine Cancer
Males
All Races Sex-specific cancer type
White
Black
Asian/Pacific Islander
American Indian/Alaska Native
Hispanic
Non-Hispanic
Females
All Races 4.9
White 4.5
Black 8.7
Asian/Pacific Islander 3.2
American Indian/Alaska Native 3.5
Hispanic 4.1
Non-Hispanic 5.0

U.S. 2014–2018, Age-Adjusted

Percent of Deaths by Age Group: Uterine Cancer
Age Range Percent of Deaths
<20 0.0%
20–34 0.4%
35–44 1.8%
45–54 7.0%
55–64 22.8%
65–74 32.9%
75–84 22.5%
>84 12.7%

The percent of uterine cancer deaths is highest among women aged 65–74.

Median Age
At Death

70

U.S. 2014–2018, All Races, Females

Trends in Rates

Changes Over Time

Keeping track of new cases, deaths, and survival over time (trends) can help scientists understand whether progress is being made and where additional research is needed to address challenges, such as improving screening or finding better treatments.

Using statistical models for analysis, age-adjusted rates for new uterine cancer cases have been rising on average 0.5% each year over 2009–2018. Age-adjusted death rates have been rising on average 1.9% each year over 2009–2018. 5-year relative survival trends are shown below.

Interactive Statistics with SEER*Explorer

With SEER*Explorer, you can...
  • Create custom graphs and tables
  • Download data and images
  • Share links to results

SEER*Explorer is an interactive website that provides easy access to a wide range of SEER cancer statistics. It provides detailed statistics for a cancer site by gender, race, calendar year, age, and for a selected number of cancer sites, by stage and histology.

Explore Additional Uterine Cancer Statistics

More About This Cancer

Cancer and the Uterus

Figure: Female Reproductive Anatomy

Figure: Anatomy of the female reproductive system; drawing shows the uterus, myometrium (muscular outer layer of the uterus), endometrium (inner lining of the uterus), ovaries, fallopian tubes, cervix, and vagina.

Uterine cancer is a disease in which malignant (cancer) cells form in the tissues of the endometrium.

The endometrium is the lining of the uterus, a hollow, muscular organ in a woman’s pelvis. In most non-pregnant women, the uterus is about 3 inches long. The lower, narrow end of the uterus is the cervix, which leads to the vagina.

Additional Information

More Information

Here are some resources for learning more about uterine cancer.

References

All statistics in this report are based on statistics from SEER and the Centers for Disease Control and Prevention's National Center for Health Statistics. Most can be found within SEER*Explorer.

Suggested Citation

All material in this report is in the public domain and may be reproduced or copied without permission; citation as to source, however, is appreciated.

SEER Cancer Stat Facts: Uterine Cancer. National Cancer Institute. Bethesda, MD, https://seer.cancer.gov/statfacts/html/corp.html

These stat facts focus on population statistics that are based on the U.S. population. Because these statistics are based on large groups of people, they cannot be used to predict exactly what will happen to an individual patient. To see tailored statistics, browse SEER*Explorer. To see statistics for a specific state, go to the State Cancer Profiles.

The statistics presented in these stat facts are based on the most recent data available, most of which can be found in SEER*Explorer. In some cases, different year spans may be used.

Estimates of new cases and deaths for 2021 are projections made by the American Cancer Society (ACS), based on earlier reported data.

Cancer is a complex topic. There is a wide range of information available. These stat facts do not address causes, symptoms, diagnosis, treatment, follow-up care, or decision making, although links are provided to information in many of these areas.