Statistics at a Glance
At a Glance
Estimated New Cases in 2022 13,190
% of All New Cancer Cases 0.7%
Estimated Deaths in 2022 5,130
% of All Cancer Deaths 0.8%
|Year||Rate of New Cases — SEER 8||Rate of New Cases — SEER 12||Death Rate — U.S.||5-Year Relative Survival — SEER 8|
|Observed||Modeled Trend||Observed||Modeled Trend||Observed||Modeled Trend||Observed||Modeled Trend|
New cases come from SEER 12. Deaths come from U.S. Mortality.
All Races, Both Sexes. Rates are Age-Adjusted.
Modeled trend lines were calculated from the underlying rates using the Joinpoint Trend Analysis Software.
New cases are also referred to as incident cases in other publications. Rates of new cases are also referred to as incidence rates.
Rate of New Cases and Deaths per 100,000: The rate of new cases of soft tissue cancer was 3.4 per 100,000 men and women per year. The death rate was 1.3 per 100,000 men and women per year. These rates are age-adjusted and based on 2015–2019 cases and 2016–2020 deaths.
Lifetime Risk of Developing Cancer: Approximately 0.3 percent of men and women will be diagnosed with soft tissue cancer at some point during their lifetime, based on 2017–2019 data.
Prevalence of This Cancer: In 2019, there were an estimated 160,079 people living with soft tissue cancer in the United States.
How Many People Survive 5 Years Or More after Being Diagnosed with Soft Tissue Cancer?
Relative survival is an estimate of the percentage of patients who would be expected to survive the effects of their cancer. It excludes the risk of dying from other causes. Because survival statistics are based on large groups of people, they cannot be used to predict exactly what will happen to an individual patient. No two patients are entirely alike, and treatment and responses to treatment can vary greatly.
Based on data from SEER 17 2012–2018. Gray figures represent those who have died from soft tissue cancer. Green figures represent those who have survived 5 years or more.
Survival by Stage
Cancer stage at diagnosis, which refers to extent of a cancer in the body, determines treatment options and has a strong influence on the length of survival. In general, if the cancer is found only in the part of the body where it started it is localized (sometimes referred to as stage 1). If it has spread to a different part of the body, the stage is regional or distant. The earlier soft tissue cancer is caught, the better chance a person has of surviving five years after being diagnosed. For soft tissue cancer, 59.1% are diagnosed at the local stage. The 5-year relative survival for localized soft tissue cancer is 81.5%.
|Stage||Percent of Cases||5-Year Relative Survival|
Confined to Primary Site
Spread to Regional Lymph Nodes
Cancer Has Metastasized
SEER 17 2012–2018, All Races, Both Sexes by SEER Combined Summary Stage
New Cases and Deaths
How Common Is This Cancer?
Compared to other cancers, soft tissue cancer is rare.
|Rank||Common Types of Cancer||Estimated New
|1.||Breast Cancer (Female)||287,850||43,250|
|3.||Lung and Bronchus Cancer||236,740||130,180|
|5.||Melanoma of the Skin||99,780||7,650|
|8.||Kidney and Renal Pelvis Cancer||79,000||13,920|
|21.||Soft Tissue Cancer||13,190||5,130|
Soft tissue cancer represents 0.7% of all new cancer cases in the U.S.
In 2022, it is estimated that there will be 13,190 new cases of soft tissue cancer and an estimated 5,130 people will die of this disease.
Who Gets This Cancer?
Soft tissue cancer is more common in men than women. Past treatment with radiation therapy, exposure to chemicals such as arsenic, and having certain inherited disorders like retinoblastoma are associated with this cancer. The rate of new cases of soft tissue cancer was 3.4 per 100,000 men and women per year based on 2015–2019 cases, age-adjusted.
|Non-Hispanic Asian/Pacific Islander||3.3|
|Non-Hispanic American Indian/Alaska Native||4.4|
|Non-Hispanic Asian/Pacific Islander||2.3|
|Non-Hispanic American Indian/Alaska Native||2.4|
SEER 22 2015–2019, Age-Adjusted
|Age Range||Percent of New Cases|
Soft tissue cancer is most frequently diagnosed among people aged 65–74.
SEER 22 2015–2019, All Races, Both Sexes
Who Dies From This Cancer?
For soft tissue cancer, death rates increase with age. Men are slightly more likely than women to die of this cancer. The death rate was 1.3 per 100,000 men and women per year based on 2016–2020 deaths, age-adjusted.
|Non-Hispanic Asian/Pacific Islander||1.0|
|Non-Hispanic American Indian/Alaska Native||1.3|
|Non-Hispanic Asian/Pacific Islander||0.8|
|Non-Hispanic American Indian/Alaska Native||1.2|
U.S. 2016–2020, Age-Adjusted
|Age Range||Percent of Deaths|
The percent of soft tissue cancer deaths is highest among people aged 65–74.
U.S. 2016–2020, All Races, Both Sexes
Trends in Rates
Changes Over Time
Keeping track of new cases, deaths, and survival over time (trends) can help scientists understand whether progress is being made and where additional research is needed to address challenges, such as improving screening or finding better treatments.
Using statistical models for analysis, age-adjusted rates for new soft tissue cancer cases have not changed significantly over 2010–2019. Age-adjusted death rates have been rising on average 0.2% each year over 2011–2020. 5-year relative survival trends are shown below.
Interactive Statistics with SEER*Explorer
- Create custom graphs and tables
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SEER*Explorer is an interactive website that provides easy access to a wide range of SEER cancer statistics. It provides detailed statistics for a cancer site by gender, race, calendar year, age, and for a selected number of cancer sites, by stage and histology.Explore Additional Soft Tissue Cancer Statistics
More About This Cancer
Soft Tissue Cancer
Soft tissue cancer occurs when cancerous (malignant) cells form in the soft tissues of the body. Soft tissues of the body include the heart, muscles, tendons, fat, blood vessels, lymph vessels, nerves and tissues around joints.
Soft tissue cancers can form almost anywhere in the body, but are most common in the head, neck, arm, legs, trunk, and abdomen. A sign of soft tissue cancer is a lump or swelling in soft tissue of the body. Soft tissue cancers can be diagnosed with a biopsy.
There are many types of soft tissue cancers, including:
Here are some resources for learning more about soft tissue cancer.
- More about why cardiac tumors are so rare
- More about risk factors for soft tissue sarcoma
- More about treatment options for soft tissue sarcoma
- More about treatment options for recurrent soft tissue sarcoma
- More about clinical trials
- More about cancer prevention
- More about coping with cancer
All statistics in this report are based on statistics from SEER and the Centers for Disease Control and Prevention's National Center for Health Statistics. Most can be found within SEER*Explorer.
All material in this report is in the public domain and may be reproduced or copied without permission; citation as to source, however, is appreciated.
SEER Cancer Stat Facts: Soft Tissue Cancer. National Cancer Institute. Bethesda, MD, https://seer.cancer.gov/statfacts/html/soft.html
These stat facts focus on population statistics that are based on the U.S. population. Because these statistics are based on large groups of people, they cannot be used to predict exactly what will happen to an individual patient. To see tailored statistics, browse SEER*Explorer. To see statistics for a specific state, go to the State Cancer Profiles.
The statistics presented in these stat facts are based on the most recent data available, most of which can be found in SEER*Explorer. In some cases, different year spans may be used.
Estimates of new cases and deaths for 2022 are projections made by the American Cancer Society (ACS), based on earlier reported data.
Cancer is a complex topic. There is a wide range of information available. These stat facts do not address causes, symptoms, diagnosis, treatment, follow-up care, or decision making, although links are provided to information in many of these areas.